PMID- 36684337
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230201
IS  - 2296-875X (Print)
IS  - 2296-875X (Electronic)
IS  - 2296-875X (Linking)
VI  - 9
DP  - 2022
TI  - Case Report: Using Medtronic AP360 mechanical prosthesis in mitral valve 
      replacement for patients with mitral insufficiency after primum atrial septal 
      defect repair to reduce left ventricular outflow tract obstruction risk.
PG  - 1008444
LID - 10.3389/fsurg.2022.1008444 [doi]
LID - 1008444
AB  - BACKGROUND: Atrial septal defect is one of the most common congenital heart 
      diseases in adults. Primum atrial septal defect (PASD) accounts for 4%-5% of 
      congenital heart defects. Patients with PASD frequently suffer mitral 
      insufficiency (MI), and thus, mitral valvuloplasty (MVP) or mitral valve 
      replacement (MVR) is often required at the time of PASD repair. Unfortunately, 
      recurrent unrepairable severe mitral regurgitation can develop in many patients 
      undergoing PASD repair plus MVP in either short- or long-term after the repair 
      surgery, requiring a re-do MVR. In those patients, the risk of left ventricular 
      outflow tract obstruction (LVOTO) has increased. CASE PRESENTATION: We present 
      five such cases, ranging in age from 24 to 47 years, who had a PASD repair plus 
      MVP or MVR for 14-40 years while suffering moderate to severe mitral 
      regurgitation. Using Medtronic AP360 mechanical mitral prostheses, only one 
      patient experienced mild LVOTO. CONCLUSIONS: The use of Medtronic AP360 
      mechanical mitral prostheses to perform MVR in patients with MI who had a history 
      of PASD repair can potentially reduce the risk of LVOTO. Long-term follow-up is 
      required to further confirm this clinical benefit associated with AP360 
      implantation in patients with PASD.
CI  - (c) 2023 Guo, Yang, Han, Zhao, Chen, Zheng and Ni.
FAU - Guo, Lei
AU  - Guo L
AD  - Department of Cardiovascular Surgery, The First Affiliated Hospital, College of 
      Medicine, Zhejiang University, Hangzhou, China.
FAU - Yang, Qiqi
AU  - Yang Q
AD  - Department of Cardiovascular Surgery, The First Affiliated Hospital, College of 
      Medicine, Zhejiang University, Hangzhou, China.
FAU - Han, Yu
AU  - Han Y
AD  - Department of Cardiovascular Surgery, The First Affiliated Hospital, College of 
      Medicine, Zhejiang University, Hangzhou, China.
FAU - Zhao, Haige
AU  - Zhao H
AD  - Department of Cardiovascular Surgery, The First Affiliated Hospital, College of 
      Medicine, Zhejiang University, Hangzhou, China.
FAU - Chen, Liangwei
AU  - Chen L
AD  - Department of Cardiovascular Surgery, The First Affiliated Hospital, College of 
      Medicine, Zhejiang University, Hangzhou, China.
FAU - Zheng, Junnan
AU  - Zheng J
AD  - Department of Cardiovascular Surgery, The First Affiliated Hospital, College of 
      Medicine, Zhejiang University, Hangzhou, China.
FAU - Ni, Yiming
AU  - Ni Y
AD  - Department of Cardiovascular Surgery, The First Affiliated Hospital, College of 
      Medicine, Zhejiang University, Hangzhou, China.
LA  - eng
PT  - Case Reports
DEP - 20230106
PL  - Switzerland
TA  - Front Surg
JT  - Frontiers in surgery
JID - 101645127
PMC - PMC9852323
OTO - NOTNLM
OT  - LVOTO
OT  - MVR
OT  - PASD repair
OT  - case report
OT  - congenital heart disease
COIS- The authors declare that the research was conducted in the absence of any 
      commercial or financial relationships that could be construed as a potential 
      conflict of interest.
EDAT- 2023/01/24 06:00
MHDA- 2023/01/24 06:01
PMCR- 2023/01/06
CRDT- 2023/01/23 04:22
PHST- 2022/07/31 00:00 [received]
PHST- 2022/10/17 00:00 [accepted]
PHST- 2023/01/23 04:22 [entrez]
PHST- 2023/01/24 06:00 [pubmed]
PHST- 2023/01/24 06:01 [medline]
PHST- 2023/01/06 00:00 [pmc-release]
AID - 10.3389/fsurg.2022.1008444 [doi]
PST - epublish
SO  - Front Surg. 2023 Jan 6;9:1008444. doi: 10.3389/fsurg.2022.1008444. eCollection 
      2022.