PMID- 36687720
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230201
IS  - 2296-861X (Print)
IS  - 2296-861X (Electronic)
IS  - 2296-861X (Linking)
VI  - 9
DP  - 2022
TI  - Analysis of malnutrition factors for inpatients with chronic kidney disease.
PG  - 1002498
LID - 10.3389/fnut.2022.1002498 [doi]
LID - 1002498
AB  - OBJECTIVE: Malnutrition is a common complication of Chronic Kidney Disease (CKD), 
      and it is the risk factor of CKD prognosis. This study aim to evaluate the 
      nutritional status of inpatients with CKD by using the Subjective Global 
      Assessment (SGA), and to analyze the related factors of malnutrition; and to 
      provide effective reference for early detection of malnutrition status in 
      patients with CKD and timely nutrition intervention. METHODS: A total of 426 
      patients (238 male patients, 188 female patients) aged 62.62 +/- 14.61 and 61.14 +/- 
      14.82, respectively admitted to the Nephrology Department of Wannan Medical 
      College from February 2020 to December 2020 were selected and included in to this 
      study by convenience sampling. 426 patients with CKD were evaluated by SGA. Human 
      body weight, hemoglobin (Hb), total protein (TP), albumin (ALB), pre-albumin 
      (PA), qualitative analysis of urinary protein and other laboratory indexes were 
      collected and measured. The correlation between malnutrition and age, education, 
      gender, diet, CKD stage and other factors was analyzed by spearman correlation 
      analysis. RESULTS: The incidence of malnutrition was 85.7% among 426 patients 
      with CKD. Gender, age, education level, CKD stage, diabetes mellitus, weight loss 
      and reduced food intake were related to SGA nutritional assessment (P < 0.05). 
      The expression levels of ALB, PA and Hb in the malnutrition group were 
      significantly lower than those in the normal group (P < 0.05). The degree of 
      malnutrition in CKD patients was significant negatively correlated with the 
      expression levels of ALB (r = -0.188), PA (r = -0.262) and Hb (r = -0.176) (P < 
      0.05). The multivariate Logistic regression analysis model showed that female (OR 
      = 2.155), >/=60 years old (OR = 7.671), weight loss (OR = 10.691), reduced food 
      intake (OR = 28.953), moderate and severe serum ALB expression (OR = 3.391 and 
      8.326) were risk factors for malnutrition in patients with CKD (P < 0.05). 
      Malnutrition was correlated with the results of qualitative examination of 
      urinary protein (r = 0.268, P < 0.05). CONCLUSION: Gender, age, weight loss, 
      reduced food intake, serum ALB expression were independently associated with 
      malnutrition in patients with chronic kidney disease, Hence, the medical staff 
      should take timely and effective nutrition intervention for the patients with 
      malnutrition, delay the renal function damage of patients with CKD and improve 
      the quality of life of patients. Inpatients with CKD, especially women, should 
      increase their dietary intake, maintain normal weight and improve their 
      nutritional status.
CI  - Copyright (c) 2023 Xi, Wu, Liang, Wang and Cao.
FAU - Xi, Wei-Zhen
AU  - Xi WZ
AD  - Kidney Internal Medicine, The First Affiliated Hospital of Wannan Medical 
      College, Wuhu Anhui, China.
FAU - Wu, Chen
AU  - Wu C
AD  - Kidney Internal Medicine, The First Affiliated Hospital of Wannan Medical 
      College, Wuhu Anhui, China.
FAU - Liang, Ya-Li
AU  - Liang YL
AD  - Kidney Internal Medicine, The First Affiliated Hospital of Wannan Medical 
      College, Wuhu Anhui, China.
FAU - Wang, Ling-Ling
AU  - Wang LL
AD  - Kidney Internal Medicine, The First Affiliated Hospital of Wannan Medical 
      College, Wuhu Anhui, China.
FAU - Cao, Yu-Han
AU  - Cao YH
AD  - Kidney Internal Medicine, The First Affiliated Hospital of Wannan Medical 
      College, Wuhu Anhui, China.
LA  - eng
PT  - Journal Article
DEP - 20230106
PL  - Switzerland
TA  - Front Nutr
JT  - Frontiers in nutrition
JID - 101642264
PMC - PMC9852827
OTO - NOTNLM
OT  - SGA nutritional assessment
OT  - chronic kidney disease
OT  - malnutrition
OT  - public health
OT  - treatment
COIS- The authors declare that the research was conducted in the absence of any 
      commercial or financial relationships that could be construed as a potential 
      conflict of interest.
EDAT- 2023/01/24 06:00
MHDA- 2023/01/24 06:01
PMCR- 2022/01/01
CRDT- 2023/01/23 05:07
PHST- 2022/07/25 00:00 [received]
PHST- 2022/11/21 00:00 [accepted]
PHST- 2023/01/23 05:07 [entrez]
PHST- 2023/01/24 06:00 [pubmed]
PHST- 2023/01/24 06:01 [medline]
PHST- 2022/01/01 00:00 [pmc-release]
AID - 10.3389/fnut.2022.1002498 [doi]
PST - epublish
SO  - Front Nutr. 2023 Jan 6;9:1002498. doi: 10.3389/fnut.2022.1002498. eCollection 
      2022.