PMID- 36690712
OWN - NLM
STAT- MEDLINE
DCOM- 20230125
LR  - 20231121
IS  - 2045-2322 (Electronic)
IS  - 2045-2322 (Linking)
VI  - 13
IP  - 1
DP  - 2023 Jan 23
TI  - A retrospective analysis of the incidence of severe adverse events among 
      recipients of chiropractic spinal manipulative therapy.
PG  - 1254
LID - 10.1038/s41598-023-28520-4 [doi]
LID - 1254
AB  - This study examined the incidence and severity of adverse events (AEs) of 
      patients receiving chiropractic spinal manipulative therapy (SMT), with the 
      hypothesis that < 1 per 100,000 SMT sessions results in a grade >/= 3 (severe) AE. 
      A secondary objective was to examine independent predictors of grade >/= 3 AEs. We 
      identified patients with SMT-related AEs from January 2017 through August 2022 
      across 30 chiropractic clinics in Hong Kong. AE data were extracted from a 
      complaint log, including solicited patient surveys, complaints, and clinician 
      reports, and corroborated by medical records. AEs were independently graded 1-5 
      based on severity (1-mild, 2-moderate, 3-severe, 4-life-threatening, 5-death). 
      Among 960,140 SMT sessions for 54,846 patients, 39 AEs were identified, two were 
      grade 3, both of which were rib fractures occurring in women age > 60 with 
      osteoporosis, while none were grade >/= 4, yielding an incidence of grade >/= 3 AEs 
      of 0.21 per 100,000 SMT sessions (95% CI 0.00, 0.56 per 100,000). There were no 
      AEs related to stroke or cauda equina syndrome. The sample size was insufficient 
      to identify predictors of grade >/= 3 AEs using multiple logistic regression. In 
      this study, severe SMT-related AEs were reassuringly very rare.
CI  - (c) 2023. The Author(s).
FAU - Chu, Eric Chun-Pu
AU  - Chu EC
AUID- ORCID: 0000-0002-0893-556X
AD  - New York Chiropractic and Physiotherapy Centre, EC Healthcare, 41/F Langham Place 
      Office Tower, 8 Argyle Street, Kowloon, Hong Kong.
FAU - Trager, Robert J
AU  - Trager RJ
AUID- ORCID: 0000-0002-4714-1076
AD  - Connor Whole Health, University Hospitals Cleveland Medical Center, 11000 Euclid 
      Ave, Cleveland, OH, 44106, USA. Robert.Trager@UHhospitals.org.
AD  - College of Chiropractic, Logan University, Chesterfield, MO, 63017, USA. 
      Robert.Trager@UHhospitals.org.
FAU - Lee, Linda Yin-King
AU  - Lee LY
AUID- ORCID: 0000-0002-8588-3556
AD  - School of Nursing and Health Studies, Hong Kong Metropolitan University, Kowloon, 
      Hong Kong.
FAU - Niazi, Imran Khan
AU  - Niazi IK
AUID- ORCID: 0000-0001-8752-7224
AD  - Centre for Chiropractic Research, New Zealand College of Chiropractic, Auckland, 
      1060, New Zealand.
LA  - eng
PT  - Journal Article
DEP - 20230123
PL  - England
TA  - Sci Rep
JT  - Scientific reports
JID - 101563288
SB  - IM
MH  - Humans
MH  - Female
MH  - *Chiropractic
MH  - Retrospective Studies
MH  - Incidence
MH  - *Manipulation, Spinal/methods
MH  - Hong Kong
PMC - PMC9870863
COIS- The authors declare no competing interests.
EDAT- 2023/01/24 06:00
MHDA- 2023/01/26 06:00
PMCR- 2023/01/23
CRDT- 2023/01/23 23:18
PHST- 2022/09/22 00:00 [received]
PHST- 2023/01/19 00:00 [accepted]
PHST- 2023/01/23 23:18 [entrez]
PHST- 2023/01/24 06:00 [pubmed]
PHST- 2023/01/26 06:00 [medline]
PHST- 2023/01/23 00:00 [pmc-release]
AID - 10.1038/s41598-023-28520-4 [pii]
AID - 28520 [pii]
AID - 10.1038/s41598-023-28520-4 [doi]
PST - epublish
SO  - Sci Rep. 2023 Jan 23;13(1):1254. doi: 10.1038/s41598-023-28520-4.