PMID- 36704406
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230202
IS  - 1662-5129 (Print)
IS  - 1662-5129 (Electronic)
IS  - 1662-5129 (Linking)
VI  - 16
DP  - 2022
TI  - The olfactory limbus of the red fox (Vulpes vulpes). New insights regarding a 
      noncanonical olfactory bulb pathway.
PG  - 1097467
LID - 10.3389/fnana.2022.1097467 [doi]
LID - 1097467
AB  - Introduction: The olfactory system in most mammals is divided into several 
      subsystems based on the anatomical locations of the neuroreceptor cells involved 
      and the receptor families that are expressed. In addition to the main olfactory 
      system and the vomeronasal system, a range of olfactory subsystems converge onto 
      the transition zone located between the main olfactory bulb (MOB) and the 
      accessory olfactory bulb (AOB), which has been termed the olfactory limbus (OL). 
      The OL contains specialized glomeruli that receive noncanonical sensory 
      afferences and which interact with the MOB and AOB. Little is known regarding the 
      olfactory subsystems of mammals other than laboratory rodents. Methods: We have 
      focused on characterizing the OL in the red fox by performing general and 
      specific histological stainings on serial sections, using both single and double 
      immunohistochemical and lectin-histochemical labeling techniques. Results: As a 
      result, we have been able to determine that the OL of the red fox (Vulpes vulpes) 
      displays an uncommonly high degree of development and complexity. Discussion: 
      This makes this species a novel mammalian model, the study of which could improve 
      our understanding of the noncanonical pathways involved in the processing of 
      chemosensory cues.
CI  - Copyright (c) 2023 Ortiz-Leal, Torres, Vargas-Barroso, Fidalgo, Lopez-Beceiro, 
      Larriva-Sahd and Sanchez-Quinteiro.
FAU - Ortiz-Leal, Irene
AU  - Ortiz-Leal I
AD  - Faculty of Veterinary, University of Santiago de Compostela, Lugo, Spain.
FAU - Torres, Mateo V
AU  - Torres MV
AD  - Faculty of Veterinary, University of Santiago de Compostela, Lugo, Spain.
FAU - Vargas-Barroso, Victor
AU  - Vargas-Barroso V
AD  - Cellular Neuroscience, IST Austria (Institute of Science and Technology Austria), 
      Klosterneuburg, Austria.
FAU - Fidalgo, Luis Eusebio
AU  - Fidalgo LE
AD  - Faculty of Veterinary, University of Santiago de Compostela, Lugo, Spain.
FAU - Lopez-Beceiro, Ana Maria
AU  - Lopez-Beceiro AM
AD  - Faculty of Veterinary, University of Santiago de Compostela, Lugo, Spain.
FAU - Larriva-Sahd, Jorge A
AU  - Larriva-Sahd JA
AD  - Institute of Neurobiology, Universidad Nacional Autonoma de Mexico, Queretaro, 
      Mexico.
FAU - Sanchez-Quinteiro, Pablo
AU  - Sanchez-Quinteiro P
AD  - Faculty of Veterinary, University of Santiago de Compostela, Lugo, Spain.
LA  - eng
PT  - Journal Article
DEP - 20230110
PL  - Switzerland
TA  - Front Neuroanat
JT  - Frontiers in neuroanatomy
JID - 101477943
PMC - PMC9871471
OTO - NOTNLM
OT  - Canidae
OT  - fox
OT  - immunohistochemistry
OT  - lectins
OT  - olfaction
OT  - olfactory limbus
COIS- The authors declare that the research was conducted in the absence of any 
      commercial or financial relationships that could be construed as a potential 
      conflict of interest.
EDAT- 2023/01/28 06:00
MHDA- 2023/01/28 06:01
PMCR- 2022/01/01
CRDT- 2023/01/27 02:24
PHST- 2022/11/13 00:00 [received]
PHST- 2022/12/20 00:00 [accepted]
PHST- 2023/01/27 02:24 [entrez]
PHST- 2023/01/28 06:00 [pubmed]
PHST- 2023/01/28 06:01 [medline]
PHST- 2022/01/01 00:00 [pmc-release]
AID - 10.3389/fnana.2022.1097467 [doi]
PST - epublish
SO  - Front Neuroanat. 2023 Jan 10;16:1097467. doi: 10.3389/fnana.2022.1097467. 
      eCollection 2022.