PMID- 36710604
OWN - NLM
STAT- MEDLINE
DCOM- 20230330
LR  - 20240401
IS  - 1440-1754 (Electronic)
IS  - 1034-4810 (Linking)
VI  - 59
IP  - 3
DP  - 2023 Mar
TI  - Minor painful procedures in extremely preterm infants admitted to a tertiary 
      neonatal intensive care unit: Opportunities to improve pain mitigation.
PG  - 542-547
LID - 10.1111/jpc.16352 [doi]
AB  - AIM: This study aims to characterise current pain management practices in 
      extremely preterm infants (gestational age less than or equal to 28 weeks) 
      admitted to neonatal intensive care unit (NICU). METHODS: Retrospective audit 
      pertaining to patient characteristics, as well as minor painful procedures (MPP), 
      pain mitigation and pain scoring in 25 extremely preterm infants admitted to a 
      tertiary NICU in 2016 over the first 14 days of NICU admission. Opportunities to 
      bundle MPP were identified according to pre-specified criteria. Bayley Scales of 
      Infant Development, Third Edition (BSID-III) cognitive, language and motor 
      composite scores were available from the neurodevelopmental follow-up clinic at 
      12- and 24-months of corrected age. Linear mixed methods regression was used to 
      examine for correlation between increased exposure to MPP and BSID-III scores at 
      follow-up. RESULTS: Extremely preterm infants underwent an average of 
      11.24 +/- 4.12 MPP per day for the first 14 days of NICU admission. Opportunities 
      to bundle MPP were missed 75.98% (408/537) of the time; most of these were 
      invasive blood collections. A total of 12.2% (481/3933) of MPP occurred within 
      4 h of pharmacological or non-pharmacological pain mitigation. BSID-III motor 
      composite score was associated with an 11.75 (95% confidence interval 1.99, 
      21.27) decrease in patients experiencing more than or equal to the third quartile 
      of MPP in the 14 days post-NICU admission (P = 0.0329, n = 42). Association was 
      not found for BSID-III cognitive and language composite scores. CONCLUSIONS: 
      There is readily scope for quality improvement initiatives to reduce harm in 
      extremely preterm infants admitted to NICU.
CI  - (c) 2023 The Authors. Journal of Paediatrics and Child Health published by John 
      Wiley & Sons Australia, Ltd on behalf of Paediatrics and Child Health Division 
      (The Royal Australasian College of Physicians).
FAU - Fulkoski, Nick
AU  - Fulkoski N
AD  - College of Health and Medicine, Australian National University, Canberra, 
      Australian Capital Territory, Australia.
FAU - Kecskes, Zsuzsoka
AU  - Kecskes Z
AD  - College of Health and Medicine, Australian National University, Canberra, 
      Australian Capital Territory, Australia.
AD  - Department of Neonatology, Centenary Hospital for Women and Children, Canberra, 
      Australian Capital Territory, Australia.
FAU - Chaudhari, Tejasvi
AU  - Chaudhari T
AD  - College of Health and Medicine, Australian National University, Canberra, 
      Australian Capital Territory, Australia.
AD  - Department of Neonatology, Centenary Hospital for Women and Children, Canberra, 
      Australian Capital Territory, Australia.
LA  - eng
PT  - Journal Article
DEP - 20230129
PL  - Australia
TA  - J Paediatr Child Health
JT  - Journal of paediatrics and child health
JID - 9005421
SB  - IM
MH  - Humans
MH  - Male
MH  - Female
MH  - Infant, Newborn
MH  - *Infant, Extremely Premature
MH  - Intensive Care, Neonatal
MH  - Hospitalization
MH  - *Pain Management
MH  - *Pain, Procedural
MH  - Retrospective Studies
MH  - Gestational Age
OTO - NOTNLM
OT  - neonatal intensive care unit
OT  - neonatal pain
OT  - pain mitigation
OT  - procedural pain
EDAT- 2023/01/31 06:00
MHDA- 2023/03/30 06:11
CRDT- 2023/01/30 02:52
PHST- 2022/12/30 00:00 [revised]
PHST- 2022/08/13 00:00 [received]
PHST- 2023/01/19 00:00 [accepted]
PHST- 2023/03/30 06:11 [medline]
PHST- 2023/01/31 06:00 [pubmed]
PHST- 2023/01/30 02:52 [entrez]
AID - 10.1111/jpc.16352 [doi]
PST - ppublish
SO  - J Paediatr Child Health. 2023 Mar;59(3):542-547. doi: 10.1111/jpc.16352. Epub 
      2023 Jan 29.