PMID- 36729451 OWN - NLM STAT- MEDLINE DCOM- 20230313 LR - 20231220 IS - 2168-619X (Electronic) IS - 2168-6181 (Print) IS - 2168-6181 (Linking) VI - 149 IP - 3 DP - 2023 Mar 1 TI - Most-Cited Patient-Reported Outcome Measures Within Otolaryngology-Revisiting the Minimal Clinically Important Difference: A Review. PG - 261-276 LID - 10.1001/jamaoto.2022.4703 [doi] AB - IMPORTANCE: Patient-reported outcome measures (PROMs) allow clinicians and researchers to assess health-related information from a patient's perspective. These measures have been used more frequently over the last several decades, but an associated minimal clinically important difference (MCID) is needed to optimize their utility. This narrative review identified the top 100 most-cited otolaryngology-related PROM development and validation publications and assessed the presence and characteristics of the PROMs' associated MCID. OBSERVATIONS: In this narrative review, a literature search in Scopus and Web of Science was conducted on June 29, 2022, using keywords related to PROM development and validation studies in otolaryngology and reference lists. Studies that met the definition of a PROM and assessed an otolaryngologic disorder or study population were included for full-text review. After full-text review of 188 articles, the top 100 most-cited PROM development and validation publications, resulting in 106 total PROMs, were chosen for review. A total of 39 (37%) of the identified PROMs had an associated MCID. Of those reporting an MCID, 14 (35.9%) used an anchor-based method, 12 (30.8%) used a distribution-based method, 10 (25.6%) used both, and 3 (7.7%) did not specify or used neither method. Rhinology had the greatest number of PROMs with an associated MCID (16 of 24, 66%), and pediatrics had the fewest (1 of 13, 7.7%). The median number of citations of PROMs with an MCID was higher than those without an MCID. CONCLUSIONS AND RELEVANCE: The majority of the most-cited PROMs in otolaryngology lack an associated MCID. These data indicated that there are a multitude of PROMs that have been cited hundreds of times and used for decades without the ability to identify whether a particular change in score on the instrument is clinically meaningful. There is a need to determine and validate MCIDs for commonly used PROMs to aid clinical research and trial interpretation. FAU - Peterson, Andrew M AU - Peterson AM AD - Clinical Outcomes Research Office, Department of Otolaryngology-Head and Neck Surgery, Washington University School of Medicine in St Louis, St Louis, Missouri. AD - Department of Otolaryngology-Head and Neck Surgery, Washington University School of Medicine in St Louis, St Louis, Missouri. FAU - Miller, Brevin AU - Miller B AD - Clinical Outcomes Research Office, Department of Otolaryngology-Head and Neck Surgery, Washington University School of Medicine in St Louis, St Louis, Missouri. AD - University of Missouri-Kansas City School of Medicine, Kansas City. FAU - Ioerger, Patrick AU - Ioerger P AD - Clinical Outcomes Research Office, Department of Otolaryngology-Head and Neck Surgery, Washington University School of Medicine in St Louis, St Louis, Missouri. AD - University of Kansas Medical Center, Kansas City. FAU - Hentati, Firas AU - Hentati F AD - Clinical Outcomes Research Office, Department of Otolaryngology-Head and Neck Surgery, Washington University School of Medicine in St Louis, St Louis, Missouri. AD - Case Western Reserve University, Cleveland, Ohio. FAU - Doering, Michelle M AU - Doering MM AD - Becker Medical Library, Washington University School of Medicine in St Louis, St Louis, Missouri. FAU - Kallogjeri, Dorina AU - Kallogjeri D AD - Clinical Outcomes Research Office, Department of Otolaryngology-Head and Neck Surgery, Washington University School of Medicine in St Louis, St Louis, Missouri. AD - Department of Otolaryngology-Head and Neck Surgery, Washington University School of Medicine in St Louis, St Louis, Missouri. FAU - Piccirillo, Jay F AU - Piccirillo JF AD - Clinical Outcomes Research Office, Department of Otolaryngology-Head and Neck Surgery, Washington University School of Medicine in St Louis, St Louis, Missouri. AD - Department of Otolaryngology-Head and Neck Surgery, Washington University School of Medicine in St Louis, St Louis, Missouri. LA - eng GR - TL1 TR002344/TR/NCATS NIH HHS/United States GR - UL1 TR002345/TR/NCATS NIH HHS/United States PT - Journal Article PT - Research Support, N.I.H., Extramural PT - Research Support, Non-U.S. Gov't PL - United States TA - JAMA Otolaryngol Head Neck Surg JT - JAMA otolaryngology-- head & neck surgery JID - 101589542 SB - IM CIN - JAMA Otolaryngol Head Neck Surg. 2023 Mar 1;149(3):276-277. PMID: 36729483 MH - Humans MH - Child MH - *Minimal Clinically Important Difference MH - Patient Reported Outcome Measures MH - *Otolaryngology PMC - PMC10729312 MID - NIHMS1923269 COIS- Conflicts of Interest: Dr. Peterson, Dr. Kallogjeri, and Dr. Piccirillo receive royalties with the commercial use of the Nasal Outcome Score for Epistaxis in Hereditary Hemorrhagic Telangiectasia (NOSE HHT). Dr. Piccirillo receives royalties with the commercial use of the Sino-Nasal Outcome Test (SNOT) instruments. EDAT- 2023/02/03 06:00 MHDA- 2023/03/14 06:00 PMCR- 2023/12/19 CRDT- 2023/02/02 11:34 PHST- 2023/02/03 06:00 [pubmed] PHST- 2023/03/14 06:00 [medline] PHST- 2023/02/02 11:34 [entrez] PHST- 2023/12/19 00:00 [pmc-release] AID - 2801142 [pii] AID - 10.1001/jamaoto.2022.4703 [doi] PST - ppublish SO - JAMA Otolaryngol Head Neck Surg. 2023 Mar 1;149(3):261-276. doi: 10.1001/jamaoto.2022.4703.