PMID- 36732613
OWN - NLM
STAT- MEDLINE
DCOM- 20230206
LR  - 20230317
IS  - 2045-2322 (Electronic)
IS  - 2045-2322 (Linking)
VI  - 13
IP  - 1
DP  - 2023 Feb 2
TI  - Social isolation in patients with chronic limb-threatening ischemia: a 
      cross-sectional study.
PG  - 1933
LID - 10.1038/s41598-023-29197-5 [doi]
LID - 1933
AB  - Assistance by family members or friends plays important roles in the course of 
      treating patients with chronic limb-threatening ischemia (CLTI), both during 
      hospitalization and after discharge. The aim of this study was to reveal the 
      prevalence of social isolation and to explore relevant clinical backgrounds in 
      patients with CLTI presenting with tissue loss and requiring revascularization. 
      We analyzed 413 patients registered in a multicenter study in whom 
      revascularization were scheduled for CLTI with tissue loss. Social isolation was 
      analyzed by assessing the residence status of the patients and the involvement of 
      a trusted family member or friend in their daily lives and during 
      hospitalization. Patients living alone accounted for 24.5% (95% confidence 
      interval [CI] 20.1-28.8%) of the study population. Patients receiving welfare 
      were more likely to live alone (P < 0.001). For patients living alone, 21.8% (95% 
      CI 12.8-30.8%) met a trusted family member or friend in their daily lives less 
      than once per year. Younger age and receiving welfare were independently 
      associated with lower frequency of meeting the trusted person in their daily 
      lives (both P < 0.05). The adjusted odds ratio of age and receiving welfare was 
      0.44 (95% CI 0.29-0.67) per 10-year increase and 3.47 (95% CI 1.43-8.44), 
      respectively. During hospitalization, 9.9% (95% CI 6.8-13.0%) of the patients had 
      no hospital visits by a trusted family member or friend on three key occasions: 
      the patient's first hospital visit, the preoperative explanation regarding the 
      planned operation, and the day of the operation. Younger age and receiving 
      welfare were independently associated with lower frequency of hospital visits by 
      a family member or friend (both P < 0.05). The adjusted odds ratio of age and 
      receiving welfare for no visit versus >/= 1 visit was 0.51 (0.36-0.74) per 10-year 
      increase and 5.29 (2.46-11.4), respectively. In conclusion, social isolation is 
      common among patients with CLTI, especially younger patients and those on 
      welfare. Practical countermeasures against social isolation are warranted in the 
      management of CLTI.
CI  - (c) 2023. The Author(s).
FAU - Takahara, Mitsuyoshi
AU  - Takahara M
AD  - Department of Diabetes Care Medicine, Osaka University Graduate School of 
      Medicine, 2-2 Yamadaoka, Suita, Osaka, 565-0871, Japan. 
      takahara@endmet.med.osaka-u.ac.jp.
FAU - Iida, Osamu
AU  - Iida O
AD  - Cardiovascular Center, Kansai Rosai Hospital, 3-1-69 Inabaso, Amagasaki, Hyogo, 
      660-8511, Japan.
FAU - Ohura, Norihiko
AU  - Ohura N
AD  - Department of Plastic, Reconstructive Surgery, Kyorin University School of 
      Medicine, 6-20-2 Shinkawa, Mitaka, Tokyo, 181-0004, Japan.
FAU - Soga, Yoshimitsu
AU  - Soga Y
AD  - Department of Cardiology, Kokura Memorial Hospital, 3-2-1 Asano, Kokurakita-Ku, 
      Kitakyushu, Fukuoka, 802-0001, Japan.
FAU - Yamaoka, Terutoshi
AU  - Yamaoka T
AD  - Department of Vascular Surgery, Matsuyama Red Cross Hospital, 1 Bunkyo-Cho, 
      Matsuyama, Ehime, 790-8524, Japan.
FAU - Azuma, Nobuyoshi
AU  - Azuma N
AD  - Department of Vascular Surgery, Asahikawa Medical University, 2-1 
      Midorigaoka-Higashi, Asahikawa, 078-8510, Japan.
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
PT  - Research Support, Non-U.S. Gov't
DEP - 20230202
PL  - England
TA  - Sci Rep
JT  - Scientific reports
JID - 101563288
SB  - IM
MH  - Humans
MH  - Chronic Limb-Threatening Ischemia
MH  - Cross-Sectional Studies
MH  - Risk Factors
MH  - *Endovascular Procedures
MH  - *Peripheral Arterial Disease
MH  - Treatment Outcome
MH  - Ischemia
MH  - Limb Salvage
MH  - Social Isolation
MH  - Retrospective Studies
MH  - Chronic Disease
PMC - PMC9894975
COIS- The authors declare no competing interests.
EDAT- 2023/02/03 06:00
MHDA- 2023/02/07 06:00
PMCR- 2023/02/02
CRDT- 2023/02/02 23:49
PHST- 2022/11/11 00:00 [received]
PHST- 2023/01/31 00:00 [accepted]
PHST- 2023/02/02 23:49 [entrez]
PHST- 2023/02/03 06:00 [pubmed]
PHST- 2023/02/07 06:00 [medline]
PHST- 2023/02/02 00:00 [pmc-release]
AID - 10.1038/s41598-023-29197-5 [pii]
AID - 29197 [pii]
AID - 10.1038/s41598-023-29197-5 [doi]
PST - epublish
SO  - Sci Rep. 2023 Feb 2;13(1):1933. doi: 10.1038/s41598-023-29197-5.