PMID- 36739118
OWN - NLM
STAT- MEDLINE
DCOM- 20230208
LR  - 20230208
IS  - 2173-5743 (Electronic)
IS  - 2173-5743 (Linking)
VI  - 19
IP  - 2
DP  - 2023 Feb
TI  - Systemic lupus erythematosus myocarditis after COVID-19 vaccination.
PG  - 114-116
LID - S2173-5743(23)00012-6 [pii]
LID - 10.1016/j.reumae.2022.06.006 [doi]
AB  - INTRODUCTION: Cases of acute myocarditis have been after administration of the 
      BNT162b2 and Ad26.COV2.S vaccine. OBJECTIVE: Describe another possible mechanism 
      of myocarditis after COVID-19 vaccination. CASE PRESENTATION: We describe the 
      clinical case of a 72-year-old female with pleuritic chest pain one week after 
      the third of the BNT162b2 mRNA vaccine. Serological tests for cardiotropic 
      pathogens were negative, and autoimmunity screening was positive with 
      anti-nuclear antibody (ANA) in 1:160 dilution, Anti-double-stranded DNA 
      (anti-dsDNA), and anti-histone antibodies. (18)F-fluoro-deoxy-glucose (FDG) 
      positron emission tomography/computed tomography (PET/CT) showed a focal 
      myocardial and pericardial inflammatory process in the cardiac apex. RESULTS AND 
      DISCUSSION: Systemic lupus erythematosus (SLE) diagnosis was made with myocardial 
      affection. As far as we know, this is the first report of a case of lupus 
      myocarditis after the COVID-19 vaccine. CONCLUSION: Given the pathogenic 
      rationales, the association between SLE and myocarditis should be considered.
CI  - Copyright (c) 2022 Elsevier Espana, S.L.U. and Sociedad Espanola de Reumatologia y 
      Colegio Mexicano de Reumatologia. All rights reserved.
FAU - Sogbe, Miguel
AU  - Sogbe M
AD  - Internal Medicine Department, Clinica Universidad de Navarra, Pamplona, Spain. 
      Electronic address: msogbe@unav.es.
FAU - Blanco-Di Matteo, Andres
AU  - Blanco-Di Matteo A
AD  - Internal Medicine Department, Clinica Universidad de Navarra, Pamplona, Spain.
FAU - Di Frisco, I Madeleine
AU  - Di Frisco IM
AD  - Pulmonary Medicine Department, Clinica Universidad de Navarra, Pamplona, Spain.
FAU - Bastidas, Juan Fernando
AU  - Bastidas JF
AD  - Nuclear Medicine Department, Clinica Universidad de Navarra, Pamplona, Spain.
FAU - Salterain, Nahikari
AU  - Salterain N
AD  - Department of Cardiology, Clinica Universidad de Navarra, Pamplona, Spain.
FAU - Gavira, Juan Jose
AU  - Gavira JJ
AD  - Department of Cardiology, Clinica Universidad de Navarra, Pamplona, Spain.
LA  - eng
PT  - Case Reports
PL  - Spain
TA  - Reumatol Clin (Engl Ed)
JT  - Reumatologia clinica
JID - 101717526
RN  - JT2NS6183B (Ad26COVS1)
RN  - 0 (Antibodies, Antinuclear)
RN  - 0 (BNT162 Vaccine)
RN  - 0 (COVID-19 Vaccines)
SB  - IM
MH  - Aged
MH  - Female
MH  - Humans
MH  - Ad26COVS1
MH  - Antibodies, Antinuclear
MH  - BNT162 Vaccine
MH  - *COVID-19/prevention & control
MH  - *COVID-19 Vaccines/adverse effects
MH  - *Lupus Erythematosus, Systemic/diagnosis
MH  - *Myocarditis/diagnosis/etiology
MH  - Positron Emission Tomography Computed Tomography
MH  - Vaccination
PMC - PMC9892927
OTO - NOTNLM
OT  - ARN mensajero BNT162B2
OT  - BNT162B2 messenger RNA
OT  - COVID-19 vaccination
OT  - Lupus eritematoso sistemico
OT  - Miocarditis
OT  - Myocarditis
OT  - Systemic lupus erythematosus
OT  - Vacunacion COVID-19
EDAT- 2023/02/05 06:00
MHDA- 2023/02/08 06:00
PMCR- 2023/02/02
CRDT- 2023/02/04 20:57
PHST- 2022/04/11 00:00 [received]
PHST- 2022/06/27 00:00 [accepted]
PHST- 2023/02/04 20:57 [entrez]
PHST- 2023/02/05 06:00 [pubmed]
PHST- 2023/02/08 06:00 [medline]
PHST- 2023/02/02 00:00 [pmc-release]
AID - S2173-5743(23)00012-6 [pii]
AID - 10.1016/j.reumae.2022.06.006 [doi]
PST - ppublish
SO  - Reumatol Clin (Engl Ed). 2023 Feb;19(2):114-116. doi: 
      10.1016/j.reumae.2022.06.006.