PMID- 36741189
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230207
IS  - 2046-2069 (Electronic)
IS  - 2046-2069 (Linking)
VI  - 13
IP  - 4
DP  - 2023 Jan 11
TI  - Sustainable solvents for beta-diketone extraction from wheat straw wax and their 
      molecular self-assembly into nano-structured tubules for hydrophobic coatings.
PG  - 2427-2437
LID - 10.1039/d2ra07581d [doi]
AB  - Nonpolar, nonperoxide forming, sustainable and potentially bio-based solvents, 
      namely 2,2,5,5-tetramethyloxolane (TMO) and 2,5-diethyl-2,5-dimethyloxolane 
      (DEDMO), were utilized as an alternative to toxic petroleum-based hydrocarbon 
      solvents for extraction of hentriacontane-14,16-dione from waste wheat straw 
      waxes. This work is the first to report the application of DEDMO as a solvent for 
      the extraction of natural products. The sustainable methodology developed in this 
      research provided considerable advantages over previously reported systems in 
      terms of high extraction yields, excellent selectivity towards the beta-diketones 
      and low amounts of waste generated. DEDMO provided the highest recovery yield for 
      all the sustainable solvents investigated, recovering 23.7% of the wax (which is 
      a 68.8% yield of the beta-diketone). The extracted lipophilic 
      hentriacontane-14,16-dione was utilised in combination with the sustainable 
      solvents TMO or DEDMO to facilitate the creation of highly hydrophobic coatings. 
      Moreover, the use of DEDMO was found to aid in the self-assembly of 
      nano-structured tubule formation of both the unrefined wax and isolated 
      beta-diketone. Green metric evaluation using process mass intensity (PMI), E-factor, 
      solvent intensity (SI), and water intensity (WI) demonstrated that the described 
      extraction procedure for hentriacontane-14,16-dione was highly sustainable and 
      safer than the previous methodology. This sustainable manufacturing process may 
      create the potential to valorise agricultural wastes as part of a holistic 
      biorefinery.
CI  - This journal is (c) The Royal Society of Chemistry.
FAU - Noppawan, Pakin
AU  - Noppawan P
AUID- ORCID: 0000-0002-6940-9045
AD  - Department of Chemistry, Faculty of Science, Mahasarakham University Maha 
      Sarakham 44150 Thailand.
FAU - Sangon, Suwiwat
AU  - Sangon S
AD  - Materials Chemistry Research Center, Department of Chemistry and Center of 
      Excellence for Innovation in Chemistry, Faculty of Science, Khon Kaen University 
      Khon Kaen 40002 Thailand andrew@KKU.ac.th.
FAU - Chatsiri, Petcharaphorn
AU  - Chatsiri P
AD  - Materials Chemistry Research Center, Department of Chemistry and Center of 
      Excellence for Innovation in Chemistry, Faculty of Science, Khon Kaen University 
      Khon Kaen 40002 Thailand andrew@KKU.ac.th.
AD  - Vidyasirimedhi Institute of Science and Technology (VISTEC) Rayong 21210 
      Thailand.
FAU - Khunmood, Nutnicha
AU  - Khunmood N
AD  - Materials Chemistry Research Center, Department of Chemistry and Center of 
      Excellence for Innovation in Chemistry, Faculty of Science, Khon Kaen University 
      Khon Kaen 40002 Thailand andrew@KKU.ac.th.
AD  - Agilent Technologies, 22nd Floor, U Chu Liang Bldg Rama IV Road Bangrak Bangkok 
      10500 Thailand.
FAU - Aintharabunya, Suphatta
AU  - Aintharabunya S
AD  - Materials Chemistry Research Center, Department of Chemistry and Center of 
      Excellence for Innovation in Chemistry, Faculty of Science, Khon Kaen University 
      Khon Kaen 40002 Thailand andrew@KKU.ac.th.
FAU - Supanchaiyamat, Nontipa
AU  - Supanchaiyamat N
AUID- ORCID: 0000-0002-5031-4281
AD  - Materials Chemistry Research Center, Department of Chemistry and Center of 
      Excellence for Innovation in Chemistry, Faculty of Science, Khon Kaen University 
      Khon Kaen 40002 Thailand andrew@KKU.ac.th.
FAU - Hunt, Andrew J
AU  - Hunt AJ
AUID- ORCID: 0000-0003-3983-8313
AD  - Materials Chemistry Research Center, Department of Chemistry and Center of 
      Excellence for Innovation in Chemistry, Faculty of Science, Khon Kaen University 
      Khon Kaen 40002 Thailand andrew@KKU.ac.th.
LA  - eng
PT  - Journal Article
DEP - 20230117
PL  - England
TA  - RSC Adv
JT  - RSC advances
JID - 101581657
PMC - PMC9844676
COIS- There are no conflicts to declare.
EDAT- 2023/02/07 06:00
MHDA- 2023/02/07 06:01
PMCR- 2023/01/17
CRDT- 2023/02/06 03:26
PHST- 2022/11/29 00:00 [received]
PHST- 2022/12/19 00:00 [accepted]
PHST- 2023/02/06 03:26 [entrez]
PHST- 2023/02/07 06:00 [pubmed]
PHST- 2023/02/07 06:01 [medline]
PHST- 2023/01/17 00:00 [pmc-release]
AID - d2ra07581d [pii]
AID - 10.1039/d2ra07581d [doi]
PST - epublish
SO  - RSC Adv. 2023 Jan 17;13(4):2427-2437. doi: 10.1039/d2ra07581d. eCollection 2023 
      Jan 11.