PMID- 36742018 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20230301 IS - 1663-2699 (Print) IS - 1663-2699 (Electronic) IS - 1663-2699 (Linking) VI - 13 IP - 3 DP - 2022 Fall TI - Significant Visual Impairment after Short-Lasting Central Serous Chorioretinopathy. PG - 678-685 LID - 10.1159/000525924 [doi] AB - A 37-year-old man experienced two episodes of central serous chorioretinopathy (CSCR) with the onset within a 7-month period, one in each eye. The diagnosis was made based on spectral-domain optical coherence tomography (SD-OCT), fundus autofluorescence (FAF), and fluorescein angiography. The presence of subretinal neovascularization and polypoidal choroidal vasculopathy were excluded. Each CSCR episode lasted for approximately 6 months and resolved completely after laser photocoagulation (left eye) and photodynamic therapy (right eye). In the right eye, subthreshold micropulse laser treatment and oral eplerenone were initially administered because of a verteporfin shortage, but they were not effective. Final best-corrected visual acuity was 0.8 logMAR in the left eye and "counting fingers" in the right. SD-OCT revealed significant retinal thinning in both eyes despite FAF, showing no major loss of retinal pigment epithelial cells. A significant reduction of ganglion cell complex thickness occurred in the right eye. Acute CSCR can result in significant visual impairment, even when short-lasting. CI - Copyright (c) 2022 by The Author(s). Published by S. Karger AG, Basel. FAU - Gawecki, Maciej AU - Gawecki M AD - Dobry Wzrok Ophthalmological Clinic, Gdansk, Poland. FAU - Grzybowski, Andrzej AU - Grzybowski A AD - Department of Ophthalmology, University of Warmia and Mazury, Olsztyn, Poland. AD - Institute for Research in Ophthalmology, Poznan, Poland. AD - Institute for Research in Ophthalmology, Foundation for Ophthalmology Development, Poznan, Poland. FAU - Pompein-Batkiewicz, Monika AU - Pompein-Batkiewicz M AD - Department of Ophthalmology of Specialist Hospital in Wejherowo, Wejherowo, Poland. LA - eng PT - Case Reports DEP - 20220919 PL - Switzerland TA - Case Rep Ophthalmol JT - Case reports in ophthalmology JID - 101532006 PMC - PMC9896455 OTO - NOTNLM OT - Central serous chorioretinopathy OT - Fundus autofluorescence OT - Spectral-domain optical coherence tomography OT - Subretinal fluid COIS- The authors have no conflicts of interest to declare. EDAT- 2023/02/07 06:00 MHDA- 2023/02/07 06:01 PMCR- 2022/09/19 CRDT- 2023/02/06 03:39 PHST- 2022/05/16 00:00 [received] PHST- 2022/06/25 00:00 [accepted] PHST- 2023/02/06 03:39 [entrez] PHST- 2023/02/07 06:00 [pubmed] PHST- 2023/02/07 06:01 [medline] PHST- 2022/09/19 00:00 [pmc-release] AID - cop-0013-0678 [pii] AID - 10.1159/000525924 [doi] PST - epublish SO - Case Rep Ophthalmol. 2022 Sep 19;13(3):678-685. doi: 10.1159/000525924. eCollection 2022 Fall.