PMID- 36751422 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20230209 IS - 2514-2119 (Electronic) IS - 2514-2119 (Linking) VI - 7 IP - 2 DP - 2023 Feb TI - Transcatheter repair of massive primary mitral regurgitation: beyond the reach of the guidelines. PG - ytad041 LID - 10.1093/ehjcr/ytad041 [doi] LID - ytad041 AB - A 58-year-old male with prior history of mechanical aortic valve replacement (AVR) in 2009 for severe symptomatic aortic regurgitation in a bicuspid aortic valve, and since 2013 a new-onset severe asymptomatic primary mitral regurgitation (MR) due to prolapse of the anterior mitral valve leaflet (AMVL) presented himself with acute heart failure. Based on current guidelines recommendations, this patient was not eligible for transcutaneous mitral valve edge-to-edge repair (TEER), as well he was found as too high risk for conventional mitral valve repair. However, as a last resort TEER was undertaken with an unconventional strategy, which resulted in resolution of the MR and improvement of clinical, biochemical findings. CI - (c) The Author(s) 2023. Published by Oxford University Press on behalf of the European Society of Cardiology. FAU - Eerdekens, Rob AU - Eerdekens R AUID- ORCID: 0000-0003-3585-0999 AD - Department of Cardiology, Catharina Hospital Eindhoven, Michelangelolaan 2, 5623 EJ Eindhoven, The Netherlands. FAU - Bouwmeester, Sjoerd AU - Bouwmeester S AUID- ORCID: 0000-0002-8358-2231 AD - Department of Cardiology, Catharina Hospital Eindhoven, Michelangelolaan 2, 5623 EJ Eindhoven, The Netherlands. FAU - Zimmermann, Frederik M AU - Zimmermann FM AD - Department of Cardiology, Catharina Hospital Eindhoven, Michelangelolaan 2, 5623 EJ Eindhoven, The Netherlands. FAU - Brueren, Guus R G AU - Brueren GRG AD - Department of Cardiology, Catharina Hospital Eindhoven, Michelangelolaan 2, 5623 EJ Eindhoven, The Netherlands. FAU - Tonino, Pim A L AU - Tonino PAL AUID- ORCID: 0000-0002-2099-5426 AD - Department of Cardiology, Catharina Hospital Eindhoven, Michelangelolaan 2, 5623 EJ Eindhoven, The Netherlands. LA - eng PT - Case Reports DEP - 20230125 PL - England TA - Eur Heart J Case Rep JT - European heart journal. Case reports JID - 101730741 PMC - PMC9898874 OTO - NOTNLM OT - Case report OT - Mitral regurgitation OT - Transcatheter intervention OT - Valvular heart disease COIS- Conflict of interest: None declared. EDAT- 2023/02/09 06:00 MHDA- 2023/02/09 06:01 PMCR- 2023/01/25 CRDT- 2023/02/08 01:56 PHST- 2022/10/19 00:00 [received] PHST- 2022/11/23 00:00 [revised] PHST- 2023/01/20 00:00 [accepted] PHST- 2023/02/08 01:56 [entrez] PHST- 2023/02/09 06:00 [pubmed] PHST- 2023/02/09 06:01 [medline] PHST- 2023/01/25 00:00 [pmc-release] AID - ytad041 [pii] AID - 10.1093/ehjcr/ytad041 [doi] PST - epublish SO - Eur Heart J Case Rep. 2023 Jan 25;7(2):ytad041. doi: 10.1093/ehjcr/ytad041. eCollection 2023 Feb.