PMID- 36755197
OWN - NLM
STAT- MEDLINE
DCOM- 20230626
LR  - 20231206
IS  - 2701-0198 (Electronic)
IS  - 2701-0198 (Linking)
VI  - 7
IP  - 6
DP  - 2023 Jun
TI  - Catching Our Breath: Updates on the Role of Dendritic Cell Subsets in Asthma.
PG  - e2200296
LID - 10.1002/adbi.202200296 [doi]
AB  - Dendritic cells (DCs), as potent antigen presenting cells, are known to play a 
      central role in the pathophysiology of asthma. The understanding of DC biology 
      has evolved over the years to include multiple subsets of DCs with distinct 
      functions in the initiation and maintenance of asthma. Furthermore, asthma is 
      increasingly recognized as a heterogeneous disease with potentially diverse 
      underlying mechanisms. The goal of this review is to summarize the role of DCs 
      and the various subsets therein in the pathophysiology of asthma and highlight 
      some of the crucial animal models shaping the field today. Potential future 
      avenues of investigation to address existing gaps in knowledge are discussed.
CI  - (c) 2023 The Authors. Advanced Biology published by Wiley-VCH GmbH.
FAU - Lajiness, Jacquelyn D
AU  - Lajiness JD
AUID- ORCID: 0000-0003-3386-6292
AD  - Department of Pediatrics, Division of Neonatology, Indiana University School of 
      Medicine, 1030 West Michigan Street, Suite C 4600, Indianapolis, IN, 46202-5201, 
      USA.
FAU - Cook-Mills, Joan M
AU  - Cook-Mills JM
AD  - Department of Pediatrics, Department of Microbiology and Immunology, Pediatric 
      Pulmonary, Asthma, and Allergy Basic Research Program, Herman B Wells Center for 
      Pediatric Research, Indiana University School of Medicine, 1044 W. Walnut Street, 
      R4-202A, Indianapolis, IN, 46202, USA.
LA  - eng
GR  - U01 AI131337/NH/NIH HHS/United States
GR  - K12 HD000850/HD/NICHD NIH HHS/United States
GR  - R01 AI127695/AI/NIAID NIH HHS/United States
GR  - R01AI127695/NH/NIH HHS/United States
GR  - K12HD000850/NH/NIH HHS/United States
GR  - U01 AI131337/AI/NIAID NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Review
DEP - 20230208
PL  - Germany
TA  - Adv Biol (Weinh)
JT  - Advanced biology
JID - 101775319
SB  - IM
MH  - Animals
MH  - *Dendritic Cells
MH  - *Asthma
PMC - PMC10293089
MID - NIHMS1874055
OTO - NOTNLM
OT  - allergic disease
OT  - asthma
OT  - atopic disease
OT  - dendritic cells
OT  - dendritic cell subsets
EDAT- 2023/02/10 06:00
MHDA- 2023/06/26 06:41
PMCR- 2024/06/01
CRDT- 2023/02/09 00:18
PHST- 2023/01/04 00:00 [revised]
PHST- 2022/11/01 00:00 [received]
PHST- 2024/06/01 00:00 [pmc-release]
PHST- 2023/06/26 06:41 [medline]
PHST- 2023/02/10 06:00 [pubmed]
PHST- 2023/02/09 00:18 [entrez]
AID - 10.1002/adbi.202200296 [doi]
PST - ppublish
SO  - Adv Biol (Weinh). 2023 Jun;7(6):e2200296. doi: 10.1002/adbi.202200296. Epub 2023 
      Feb 8.