PMID- 36758492 OWN - NLM STAT- MEDLINE DCOM- 20230228 LR - 20230228 IS - 1873-3778 (Electronic) IS - 0021-9673 (Linking) VI - 1692 DP - 2023 Mar 15 TI - Piperazine-linked metal covalent organic framework-coated fibers for efficient electro-enhanced solid-phase microextraction of chlorophenols. PG - 463847 LID - S0021-9673(23)00075-4 [pii] LID - 10.1016/j.chroma.2023.463847 [doi] AB - Conductive covalent organic frameworks (COFs) have received considerable attention and are critical in various applications such as electro-enhanced solid-phase microextraction (EE-SPME). In this work, a novel piperazine-linked copper-doped phthalocyanine metal covalent organic framework (CuPc-MCOF) was synthesized with good stability and high electrical conductivity. The synthesized CuPc-MCOF was then used as an EE-SPME coating material for extraction of five trace chlorophenols (CPs), including 2,4-dichlorophenol (2,4-DCP), 2,6-dichlorophenol (2,6-DCP), 2,4,6-trichlorophenol (2,4,6-TCP), 2,4,5-trichlorophenol (2,4,5-TCP) and 2,4,5,6-tetrachlorophenol (2,4,5,6-TCP), exhibiting excellent extraction performance because of various synergistic forces between CuPc-MCOF fibers and CPs. By combining EE-SPME with gas chromatography-tandem mass spectrometry (GC-MS/MS), a sensitive method for CPs detection was established with a low limit of detection (0.8-5 ng L(-1)) and good reproducibility (RSD