PMID- 36760175 OWN - NLM STAT- MEDLINE DCOM- 20230705 LR - 20230705 IS - 1601-6343 (Electronic) IS - 1601-6335 (Linking) VI - 26 IP - 3 DP - 2023 Aug TI - Normal variation of mandibular asymmetry in children. PG - 524-530 LID - 10.1111/ocr.12639 [doi] AB - OBJECTIVE: To explore the normal variation of asymmetry in mandibles of children in the age group of 1 to 12 years. MATERIALS AND METHODS: The study group consisted of 92 cadaveric mandibles of children with a dental age of 1 to 12 years old in possession of ACTA (Academic Centre for Dentistry Amsterdam), Faculty of Dentistry, the Netherlands. 3D models of the mandibles were obtained from CT-scans and hemimandibular volumes of all mandibles were calculated. The condylar height, ramus height, mandibular body length and the gonial angle were bilaterally determined using a novel landmark-based method, and the degree of asymmetry was calculated. RESULTS: No relationship was found between dental age and asymmetry of the studied parameters (P < .05). The highest degree of asymmetry was found in the ramus height, whereas the gonial angle presented the lowest degree of asymmetry. A positive correlation was found between the asymmetry of the hemimandibular volume vs the height of the ramus (P < .05) and the length of the mandibular body (P < .05). An inverse correlation was found between the asymmetry of the ramus height vs the condylar height (P < .05), mandibular body length (P < .05) and gonial angle (P < .05). CONCLUSIONS: Mandibular asymmetries in children did occur (9.8% of the included mandibles presented with a relevant overall asymmetry of >/=3%) and were unrelated to age. The different segments of the mandible seem to compensate for each other, in order to maintain a functional equilibrium. CI - (c) 2023 The Authors. Orthodontics & Craniofacial Research published by John Wiley & Sons Ltd. FAU - Vespasiano, Valeria AU - Vespasiano V AUID- ORCID: 0000-0001-9737-791X AD - Department of Oral and Maxillofacial Surgery, Amsterdam University Medical Centers and Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam, Amsterdam, The Netherlands. FAU - Klop, Cornelis AU - Klop C AD - Department of Oral and Maxillofacial Surgery, Amsterdam University Medical Centers and Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam, Amsterdam, The Netherlands. FAU - Mulder, Catharina S AU - Mulder CS AD - Department of Oral and Maxillofacial Surgery, Amsterdam University Medical Centers and Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam, Amsterdam, The Netherlands. FAU - Koolstra, Jan H AU - Koolstra JH AD - Department of Functional Anatomy, Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam and Vrije Universiteit Amsterdam, Amsterdam, The Netherlands. FAU - Lobe, Nicolaas H J AU - Lobe NHJ AD - Department of Radiology and Nuclear Medicine, Amsterdam UMC (location AMC), University of Amsterdam, Amsterdam, The Netherlands. FAU - Beenen, Ludo F M AU - Beenen LFM AD - Department of Radiology and Nuclear Medicine, Amsterdam UMC (location AMC), University of Amsterdam, Amsterdam, The Netherlands. FAU - Nolte, Jitske W AU - Nolte JW AD - Department of Oral and Maxillofacial Surgery, Amsterdam University Medical Centers and Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam, Amsterdam, The Netherlands. FAU - Becking, Alfred G AU - Becking AG AD - Department of Oral and Maxillofacial Surgery, Amsterdam University Medical Centers and Academic Centre for Dentistry Amsterdam (ACTA), University of Amsterdam, Amsterdam, The Netherlands. LA - eng PT - Journal Article DEP - 20230226 PL - England TA - Orthod Craniofac Res JT - Orthodontics & craniofacial research JID - 101144387 SB - IM MH - Humans MH - Child MH - Infant MH - Child, Preschool MH - *Facial Asymmetry/diagnostic imaging MH - *Mandible/diagnostic imaging MH - Tomography, X-Ray Computed MH - Netherlands MH - Cephalometry/methods OTO - NOTNLM OT - asymmetry OT - cephalometry OT - children OT - computed tomography OT - mandible EDAT- 2023/02/11 06:00 MHDA- 2023/07/05 06:42 CRDT- 2023/02/10 02:12 PHST- 2023/01/11 00:00 [revised] PHST- 2022/11/24 00:00 [received] PHST- 2023/02/05 00:00 [accepted] PHST- 2023/07/05 06:42 [medline] PHST- 2023/02/11 06:00 [pubmed] PHST- 2023/02/10 02:12 [entrez] AID - 10.1111/ocr.12639 [doi] PST - ppublish SO - Orthod Craniofac Res. 2023 Aug;26(3):524-530. doi: 10.1111/ocr.12639. Epub 2023 Feb 26.