PMID- 36765328
OWN - NLM
STAT- MEDLINE
DCOM- 20230214
LR  - 20230214
IS  - 1471-2415 (Electronic)
IS  - 1471-2415 (Linking)
VI  - 23
IP  - 1
DP  - 2023 Feb 10
TI  - Development of an implantable collamer lens sizing model: a retrospective study 
      using ANTERION swept-source optical coherence tomography and a literature review.
PG  - 59
LID - 10.1186/s12886-023-02814-7 [doi]
LID - 59
AB  - BACKGROUND: Optimal sizing for phakic intraocular lens (EVO-ICL with KS-AquaPort) 
      implantation plays an important role in preventing postoperative complications. 
      We aimed to formulate optimal lens sizing using ocular biometric parameters 
      measured with a Heidelberg anterior segment optical coherence tomography (AS-OCT) 
      device. METHODS: We retrospectively analyzed 892 eyes of 471 healthy subjects 
      treated with an intraocular collamer lens (ICL) and assigned them to either the 
      development (80%) or validation (20%) set. We built vault prediction models using 
      the development set via classic linear regression methods as well as partial 
      least squares and least absolute shrinkage and selection operator (LASSO) 
      regression techniques. We evaluated prediction abilities based on the Bayesian 
      information criterion (BIC) to select the best prediction model. The performance 
      was measured using Pearson's correlation coefficient and the mean squared error 
      (MAE) between the achieved and predicted results. RESULTS: Measurements of 
      aqueous depth (AQD), anterior chamber volume, anterior chamber angle (ACA) 
      distance, spur-to-spur distance, crystalline lens thickness (LT), and 
      white-to-white distance from ANTERION were highly associated with the ICL vault. 
      The LASSO model using the AQD, ACA distance, and LT showed the best BIC results 
      for postoperative ICL vault prediction. In the validation dataset, the LASSO 
      model showed the strongest correlation (r = 0.582, P < 0.001) and the lowest MAE 
      (104.7 mum). CONCLUSION: This is the first study to develop a postoperative ICL 
      vault prediction and lens-sizing model based on the ANTERION. As the measurements 
      from ANTERION and other AS-OCT devices are not interchangeable, ANTERION may be 
      used for optimal ICL sizing using our formula. Because our model was developed 
      based on the East Asian population, further studies are needed to explore the 
      role of this prediction model in different populations.
CI  - (c) 2023. The Author(s).
FAU - Kim, Taein
AU  - Kim T
AD  - VISUWORKS, Seoul, South Korea.
FAU - Kim, Su Jeong
AU  - Kim SJ
AD  - VISUWORKS, Seoul, South Korea.
FAU - Lee, Bo Young
AU  - Lee BY
AD  - VISUWORKS, Seoul, South Korea.
FAU - Cho, Hye Jin
AU  - Cho HJ
AD  - VISUWORKS, Seoul, South Korea.
FAU - Sa, Beom Gi
AU  - Sa BG
AD  - VISUWORKS, Seoul, South Korea.
FAU - Ryu, Ik Hee
AU  - Ryu IH
AD  - VISUWORKS, Seoul, South Korea.
AD  - Department of Refractive Surgery, B&VIIT Eye Center, 1317-23 Seocho-Dong, 
      Seocho-Gu, Seoul, South Korea.
FAU - Kim, Jin Kuk
AU  - Kim JK
AD  - VISUWORKS, Seoul, South Korea.
AD  - Department of Refractive Surgery, B&VIIT Eye Center, 1317-23 Seocho-Dong, 
      Seocho-Gu, Seoul, South Korea.
FAU - Lee, In Sik
AU  - Lee IS
AD  - Department of Refractive Surgery, B&VIIT Eye Center, 1317-23 Seocho-Dong, 
      Seocho-Gu, Seoul, South Korea.
FAU - Han, Eoksoo
AU  - Han E
AD  - Electronics and Telecommunications Research Institute (ETRI), Daejeon, South 
      Korea.
FAU - Kim, Hyungsu
AU  - Kim H
AD  - Yonsei Eye Clinic, Seoul, South Korea.
FAU - Yoo, Tae Keun
AU  - Yoo TK
AUID- ORCID: 0000-0003-0890-8614
AD  - VISUWORKS, Seoul, South Korea. eyetaekeunyoo@gmail.com.
AD  - Department of Refractive Surgery, B&VIIT Eye Center, 1317-23 Seocho-Dong, 
      Seocho-Gu, Seoul, South Korea. eyetaekeunyoo@gmail.com.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20230210
PL  - England
TA  - BMC Ophthalmol
JT  - BMC ophthalmology
JID - 100967802
SB  - IM
MH  - Humans
MH  - Tomography, Optical Coherence/methods
MH  - Retrospective Studies
MH  - Lens Implantation, Intraocular/methods
MH  - Bayes Theorem
MH  - *Myopia/surgery
MH  - Anterior Chamber/diagnostic imaging
MH  - *Phakic Intraocular Lenses
PMC - PMC9921691
OTO - NOTNLM
OT  - ANTERION
OT  - Implantable collamer lens
OT  - Lens sizing
OT  - Postoperative vault
COIS- Ik Hee Ryu, Jin Kuk Kim, and Tae Keun Yoo are executives of VISUWORKS, Inc., 
      which is a Korean Artificial Intelligence startup that provides medical machine 
      learning solutions. Jin Kuk Kim is an executive of the Korea Intelligent Medical 
      Industry Association. They received salaries or stocks as part of their standard 
      compensation packages. The remaining authors declare no conflicts of interest.
EDAT- 2023/02/12 06:00
MHDA- 2023/02/15 06:00
PMCR- 2023/02/10
CRDT- 2023/02/11 00:03
PHST- 2022/07/28 00:00 [received]
PHST- 2023/02/09 00:00 [accepted]
PHST- 2023/02/11 00:03 [entrez]
PHST- 2023/02/12 06:00 [pubmed]
PHST- 2023/02/15 06:00 [medline]
PHST- 2023/02/10 00:00 [pmc-release]
AID - 10.1186/s12886-023-02814-7 [pii]
AID - 2814 [pii]
AID - 10.1186/s12886-023-02814-7 [doi]
PST - epublish
SO  - BMC Ophthalmol. 2023 Feb 10;23(1):59. doi: 10.1186/s12886-023-02814-7.