PMID- 36767249 OWN - NLM STAT- MEDLINE DCOM- 20230214 LR - 20240421 IS - 1660-4601 (Electronic) IS - 1661-7827 (Print) IS - 1660-4601 (Linking) VI - 20 IP - 3 DP - 2023 Jan 19 TI - The Associations of Loneliness and Social Support with Cognitive Impairment among Middle-Aged and Older Individuals with Diabetes. LID - 10.3390/ijerph20031885 [doi] LID - 1885 AB - Diabetes mellitus is a chronic disease with significant morbidity and mortality and it is associated with poor cognitive performance in later life. This study seeks to determine the relationship between social support and cognitive function among participants with type 2 diabetes mellitus (T2DM). We used data from the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study, including participants with T2DM aged 45 and older (n = 4821). We examined different aspects of perceived social support, measured as structural social support (e.g., marital status), functional social support (having a caregiver in case of sickness or disability), and loneliness. We examined cognitive functioning using a six-item screener. Our results indicate that adults who felt lonely for 5-7 days per week had almost double the odds of cognitive impairment compared to those who didn't feel lonely. These results suggest that among middle-aged and older individuals with T2DM, interventions targeting lonely adults and which aim to reduce loneliness may combat some of the risks of cognitive decline. FAU - Cohn-Schwartz, Ella AU - Cohn-Schwartz E AUID- ORCID: 0000-0001-9623-1820 AD - Department of Epidemiology, Biostatistics, and Community Health Sciences, Faculty of Health Sciences, Ben-Gurion University, Beer-Sheva 8410501, Israel. FAU - Joshi, Rennie AU - Joshi R AD - Department of Epidemiology and Biostatistics, Drexel University Dornsife School of Public Health, Philadelphia, PA 19104, USA. FAU - McClure, Leslie A AU - McClure LA AUID- ORCID: 0000-0002-2465-6739 AD - Department of Epidemiology and Biostatistics, Drexel University Dornsife School of Public Health, Philadelphia, PA 19104, USA. LA - eng GR - U01 NS041588/NS/NINDS NIH HHS/United States PT - Journal Article PT - Research Support, N.I.H., Extramural DEP - 20230119 PL - Switzerland TA - Int J Environ Res Public Health JT - International journal of environmental research and public health JID - 101238455 SB - IM MH - Middle Aged MH - Humans MH - Aged MH - Loneliness/psychology MH - *Diabetes Mellitus, Type 2/complications MH - *Cognitive Dysfunction/epidemiology/psychology MH - Social Support MH - Cognition PMC - PMC9914689 OTO - NOTNLM OT - aging OT - cognition OT - diabetes OT - family OT - friends OT - living arrangements OT - loneliness OT - support COIS- The authors declare no conflict of interest. EDAT- 2023/02/12 06:00 MHDA- 2023/02/15 06:00 PMCR- 2023/01/19 CRDT- 2023/02/11 01:12 PHST- 2022/12/18 00:00 [received] PHST- 2023/01/13 00:00 [revised] PHST- 2023/01/14 00:00 [accepted] PHST- 2023/02/11 01:12 [entrez] PHST- 2023/02/12 06:00 [pubmed] PHST- 2023/02/15 06:00 [medline] PHST- 2023/01/19 00:00 [pmc-release] AID - ijerph20031885 [pii] AID - ijerph-20-01885 [pii] AID - 10.3390/ijerph20031885 [doi] PST - epublish SO - Int J Environ Res Public Health. 2023 Jan 19;20(3):1885. doi: 10.3390/ijerph20031885.