PMID- 36773673
OWN - NLM
STAT- MEDLINE
DCOM- 20230315
LR  - 20230315
IS  - 1872-8227 (Electronic)
IS  - 0168-8227 (Linking)
VI  - 197
DP  - 2023 Mar
TI  - Severe distress & denial among Asian patients with Type 2 Diabetes Mellitus in 
      the primary care: A prospective, multicentre study.
PG  - 110574
LID - S0168-8227(23)00049-9 [pii]
LID - 10.1016/j.diabres.2023.110574 [doi]
AB  - AIMS: To determine the point-prevalence and distribution of diabetes distress 
      among primary care Asians with Type 2 Diabetes Mellitus (T2DM) and evaluate its 
      association with cardiovascular risk. METHODS: This was a prospective, 
      multicentre study conducted in two outpatient clinics. Patients aged >/= 21 years 
      with uncontrolled T2DM (HbA1c > 7.0 % [53 mmol/mol]) and polypharmacy were 
      stratified based on their Framingham Risk Score (FRS-high >/= 10 %, low < 10 %) and 
      matched in accordance to their baseline HbA1c. Cardiovascular risk was estimated 
      using FRS while diabetes distress was measured using Problem Areas in Diabetes 
      (PAID) scale (denial 0-10, severe distress >/= 40). RESULTS: Of 1940 patients 
      approached, 210 were recruited. A final 132 (62.9 %) participants were eligible 
      for analysis. Median PAID score was 17.5 (IQR 6.25-41.56), with an even 
      distribution in each distress category. There was no significant difference in 
      PAID scores between the high and low FRS groups (20.00vs13.75, p = 0.446). 
      Additionally, PAID score distribution within each group was similar 
      (McNemar-Bowker test, p = 0.477). However, a high prevalence of severe distress 
      (31.4 %) and denial (33.8 %) was detected. Among those in denial, 58.7 % had 
      accompanying intermediate-high 10-year cardiovascular risk. CONCLUSION: In our 
      sample of Asian primary care patients, a high prevalence of severe diabetes 
      distress and denial was detected although no clear association between 
      cardiovascular risk and diabetes distress was found. Future studies should assess 
      the longitudinal changes and impact of other risk factors in diabetes distress. 
      (Abstract: 199 words).
CI  - Copyright (c) 2023 Elsevier B.V. All rights reserved.
FAU - Tan, Cheryl Wei Yan
AU  - Tan CWY
AD  - National Healthcare Group Pharmacy, Singapore; Department of Pharmacy, Faculty of 
      Science, National University of Singapore, Singapore. Electronic address: 
      Cheryl_Wy_TAN@pharmacy.nhg.com.sg.
FAU - Xu, Yingqi
AU  - Xu Y
AD  - Department of Pharmacy, Faculty of Science, National University of Singapore, 
      Singapore; Health Services Research Centre, Singapore Health Services, Singapore.
FAU - Lee, Joyce Yu-Chia
AU  - Lee JY
AD  - Department of Pharmacy, Faculty of Science, National University of Singapore, 
      Singapore; School of Pharmacy and Pharmaceutical Sciences, University of 
      California, Irvine. Electronic address: j.lee@uci.edu.
LA  - eng
PT  - Journal Article
PT  - Multicenter Study
DEP - 20230209
PL  - Ireland
TA  - Diabetes Res Clin Pract
JT  - Diabetes research and clinical practice
JID - 8508335
RN  - 0 (Glycated Hemoglobin)
SB  - IM
MH  - Humans
MH  - *Diabetes Mellitus, Type 2/complications/epidemiology
MH  - Glycated Hemoglobin
MH  - Prospective Studies
MH  - Risk Factors
MH  - Primary Health Care
OTO - NOTNLM
OT  - Cardiovascular
OT  - Chronic disease
OT  - Emotional
OT  - Primary health care
OT  - Psychological
COIS- Declaration of Competing Interest The authors declare that they have no known 
      competing financial interests or personal relationships that could have appeared 
      to influence the work reported in this paper.
EDAT- 2023/02/12 06:00
MHDA- 2023/03/16 06:00
CRDT- 2023/02/11 19:23
PHST- 2020/02/12 00:00 [received]
PHST- 2023/01/29 00:00 [revised]
PHST- 2023/02/05 00:00 [accepted]
PHST- 2023/02/12 06:00 [pubmed]
PHST- 2023/03/16 06:00 [medline]
PHST- 2023/02/11 19:23 [entrez]
AID - S0168-8227(23)00049-9 [pii]
AID - 10.1016/j.diabres.2023.110574 [doi]
PST - ppublish
SO  - Diabetes Res Clin Pract. 2023 Mar;197:110574. doi: 10.1016/j.diabres.2023.110574. 
      Epub 2023 Feb 9.