PMID- 36776253
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230214
IS  - 2297-055X (Print)
IS  - 2297-055X (Electronic)
IS  - 2297-055X (Linking)
VI  - 10
DP  - 2023
TI  - Suture-based vs. pure plug-based vascular closure devices for VA-ECMO 
      decannulation-A retrospective observational study.
PG  - 1106114
LID - 10.3389/fcvm.2023.1106114 [doi]
LID - 1106114
AB  - BACKGROUND: Veno-arterial extracorporeal membrane oxygenation (VA-ECMO) is a 
      valuable treatment option for patients in cardiogenic shock, but complications 
      during decannulation may worsen the overall outcome. Therefore, the aim of this 
      study was to compare the efficacy and safety of suture-based to pure plug-based 
      vascular closure devices for VA-ECMO decannulation. METHODS: In this 
      retrospective study, the procedural outcome of 33 patients with suture-based 
      Perclose ProGlide closure devices was compared to 38 patients with MANTA 
      plug-based closure devices. RESULTS: Rate of technically correct placement of 
      closure devices was 88% in the suture-based group and 97% in the plug-based group 
      (p = 0.27). There was a significant reduction of severe bleeding events during 
      VA-ECMO decannulation in plug-based versus suture-based systems (3% vs. 21%, p = 
      0.04). Ischemic complications occurred in 6% with suture-based and 5% with 
      plug-based device (p = 1.00). Pseudoaneurysm formation was detected in 3% in both 
      groups (p = 1.00). No switch to vascular surgery due to bleeding after 
      decannulation was necessary in both groups. CONCLUSION: Based on our 
      retrospective analysis, we propose that plug-based vascular closure should be the 
      preferred option for VA-ECMO decannulation. This hypothesis should be further 
      tested in a randomized trial.
CI  - Copyright (c) 2023 Scherer, Theiss, Istrefi, Binzenhofer, Kupka, Stocker, 
      Lusebrink, Stambollxhiu, Alemic, Petzold, Stark, Deseive, Braun, Joskowiak, 
      Peterss, Hausleiter, Hagl, Massberg and Orban.
FAU - Scherer, Clemens
AU  - Scherer C
AD  - Department of Medicine I, University Hospital, LMU Munich, Munich, Germany.
AD  - German Center for Cardiovascular Research, Partner Site Munich Heart Alliance, 
      Munich, Germany.
FAU - Theiss, Hans
AU  - Theiss H
AD  - Department of Medicine I, University Hospital, LMU Munich, Munich, Germany.
AD  - German Center for Cardiovascular Research, Partner Site Munich Heart Alliance, 
      Munich, Germany.
FAU - Istrefi, Mario
AU  - Istrefi M
AD  - Department of Medicine I, University Hospital, LMU Munich, Munich, Germany.
FAU - Binzenhofer, Leonhard
AU  - Binzenhofer L
AD  - Department of Medicine I, University Hospital, LMU Munich, Munich, Germany.
AD  - German Center for Cardiovascular Research, Partner Site Munich Heart Alliance, 
      Munich, Germany.
FAU - Kupka, Danny
AU  - Kupka D
AD  - Department of Medical Oncology and Hematology, University Hospital Zurich, 
      Zurich, Switzerland.
FAU - Stocker, Thomas
AU  - Stocker T
AD  - Department of Medicine I, University Hospital, LMU Munich, Munich, Germany.
AD  - German Center for Cardiovascular Research, Partner Site Munich Heart Alliance, 
      Munich, Germany.
FAU - Lusebrink, Enzo
AU  - Lusebrink E
AD  - Department of Medicine I, University Hospital, LMU Munich, Munich, Germany.
AD  - German Center for Cardiovascular Research, Partner Site Munich Heart Alliance, 
      Munich, Germany.
FAU - Stambollxhiu, Era
AU  - Stambollxhiu E
AD  - Department of Medicine I, University Hospital, LMU Munich, Munich, Germany.
FAU - Alemic, Ahmed
AU  - Alemic A
AD  - Department of Medicine I, University Hospital, LMU Munich, Munich, Germany.
FAU - Petzold, Tobias
AU  - Petzold T
AD  - Department of Medicine I, University Hospital, LMU Munich, Munich, Germany.
AD  - German Center for Cardiovascular Research, Partner Site Munich Heart Alliance, 
      Munich, Germany.
FAU - Stark, Konstantin
AU  - Stark K
AD  - Department of Medicine I, University Hospital, LMU Munich, Munich, Germany.
AD  - German Center for Cardiovascular Research, Partner Site Munich Heart Alliance, 
      Munich, Germany.
FAU - Deseive, Simon
AU  - Deseive S
AD  - Department of Medicine I, University Hospital, LMU Munich, Munich, Germany.
AD  - German Center for Cardiovascular Research, Partner Site Munich Heart Alliance, 
      Munich, Germany.
FAU - Braun, Daniel
AU  - Braun D
AD  - Department of Medicine I, University Hospital, LMU Munich, Munich, Germany.
AD  - German Center for Cardiovascular Research, Partner Site Munich Heart Alliance, 
      Munich, Germany.
FAU - Joskowiak, Dominik
AU  - Joskowiak D
AD  - Department of Cardiac Surgery, University Hospital, LMU Munich, Munich, Germany.
FAU - Peterss, Sven
AU  - Peterss S
AD  - Department of Cardiac Surgery, University Hospital, LMU Munich, Munich, Germany.
FAU - Hausleiter, Jorg
AU  - Hausleiter J
AD  - Department of Medicine I, University Hospital, LMU Munich, Munich, Germany.
AD  - German Center for Cardiovascular Research, Partner Site Munich Heart Alliance, 
      Munich, Germany.
FAU - Hagl, Christian
AU  - Hagl C
AD  - German Center for Cardiovascular Research, Partner Site Munich Heart Alliance, 
      Munich, Germany.
AD  - Department of Cardiac Surgery, University Hospital, LMU Munich, Munich, Germany.
FAU - Massberg, Steffen
AU  - Massberg S
AD  - Department of Medicine I, University Hospital, LMU Munich, Munich, Germany.
AD  - German Center for Cardiovascular Research, Partner Site Munich Heart Alliance, 
      Munich, Germany.
FAU - Orban, Martin
AU  - Orban M
AD  - Department of Medicine I, University Hospital, LMU Munich, Munich, Germany.
AD  - German Center for Cardiovascular Research, Partner Site Munich Heart Alliance, 
      Munich, Germany.
LA  - eng
PT  - Journal Article
DEP - 20230126
PL  - Switzerland
TA  - Front Cardiovasc Med
JT  - Frontiers in cardiovascular medicine
JID - 101653388
PMC - PMC9908581
OTO - NOTNLM
OT  - MANTA
OT  - ProGlide
OT  - VA-ECMO
OT  - cardiogenic shock
OT  - plug-based closure device
OT  - suture-based closure device
OT  - veno-arterial extracorporeal membrane oxygenation
COIS- CS and SD received speaker honoraria from AstraZeneca outside the submitted work. 
      JH received speaker honoraria and research support from Abbott Vascular and 
      Edwards Lifesciences outside the submitted work. MO received speaker honoraria 
      from AstraZeneca, Abiomed, CytoSorbents, and Sedana Medical, outside the 
      submitted work. The remaining authors declare that the research was conducted in 
      the absence of any commercial or financial relationships that could be construed 
      as a potential conflict of interest.
EDAT- 2023/02/14 06:00
MHDA- 2023/02/14 06:01
PMCR- 2023/01/01
CRDT- 2023/02/13 03:16
PHST- 2022/11/23 00:00 [received]
PHST- 2023/01/10 00:00 [accepted]
PHST- 2023/02/13 03:16 [entrez]
PHST- 2023/02/14 06:00 [pubmed]
PHST- 2023/02/14 06:01 [medline]
PHST- 2023/01/01 00:00 [pmc-release]
AID - 10.3389/fcvm.2023.1106114 [doi]
PST - epublish
SO  - Front Cardiovasc Med. 2023 Jan 26;10:1106114. doi: 10.3389/fcvm.2023.1106114. 
      eCollection 2023.