PMID- 36785580
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230215
IS  - 2667-100X (Electronic)
IS  - 2667-100X (Linking)
VI  - 3
IP  - 1
DP  - 2023 Jan 31
TI  - Extracorporeal membrane oxygenation in COVID-19 associated acute respiratory 
      distress syndrome: A narrative review.
PG  - 4-10
LID - 10.1016/j.jointm.2022.08.003 [doi]
AB  - Venovenous extracorporeal membrane oxygenation (VV-ECMO) is an established rescue 
      therapy in the management of refractory acute respiratory distress syndrome 
      (ARDS). Although ECMO played an important role in previous respiratory viral 
      epidemics, concerns about the benefits and usefulness of this technique were 
      raised during the coronavirus disease 2019 (COVID-19) pandemic. Indeed, the 
      mortality rate initially reported in small case series from China was concerning 
      and exceeded 90%. A few months later, the critical care community published the 
      findings from several observational cohorts on the use of extracorporeal membrane 
      oxygenation (ECMO) in COVID-19-related ARDS. Contrary to the preliminary results, 
      data from the first surge supported the use of ECMO in experienced centers 
      because the mortality rate was comparable to those from the ECMO to Rescue Lung 
      Injury in Severe ARDS (EOLIA) trial or other large prospective studies. However, 
      the mortality rate of the population with severe disease evolved during the 
      pandemic, in conjunction with changes in the management of the disease and the 
      occurrence of new variants. The results from subsequent studies confirmed that 
      the outcomes mainly depend on strict patient selection and center expertise. In 
      comparison with non-COVID-related ARDS, the duration of ECMO for COVID-related 
      ARDS was longer and increased over time. Clinicians and decision-makers must 
      integrate this finding in the ECMO decision-making process to plan their ICU 
      capacity and resource allocation. This narrative review summarizes the current 
      evidence and specific considerations for ECMO use in COVID-19-associated ARDS.
CI  - (c) 2022 The Author(s). Published by Elsevier B.V. on behalf of Chinese Medical 
      Association.
FAU - Assouline, Benjamin
AU  - Assouline B
AD  - Medecine Intensive Reanimation, Institut de Cardiologie, Assistance 
      Publique-Hopitaux de Paris, Paris 75013, France.
FAU - Combes, Alain
AU  - Combes A
AD  - Medecine Intensive Reanimation, Institut de Cardiologie, Assistance 
      Publique-Hopitaux de Paris, Paris 75013, France.
AD  - INSERM, UMRS 1166, ICAN Institute of Cardiometabolism and Nutrition, Sorbonne 
      Universite, Paris 75013, France.
FAU - Schmidt, Matthieu
AU  - Schmidt M
AD  - Medecine Intensive Reanimation, Institut de Cardiologie, Assistance 
      Publique-Hopitaux de Paris, Paris 75013, France.
AD  - INSERM, UMRS 1166, ICAN Institute of Cardiometabolism and Nutrition, Sorbonne 
      Universite, Paris 75013, France.
LA  - eng
PT  - Journal Article
PT  - Review
DEP - 20221004
PL  - China
TA  - J Intensive Med
JT  - Journal of intensive medicine
JID - 9918539389006676
PMC - PMC9531953
OTO - NOTNLM
OT  - Acute respiratory distress syndrome (ARDS)
OT  - COVID-19
OT  - Extracorporeal membrane oxygenation (ECMO)
OT  - Mortality
COIS- Matthieu Schmidt reports lecture fees from Getinge, Drager, and Xenios outside 
      the submitted work. Alain Combes reports grants from Getinge, and personal fees 
      from Getinge, Baxter, and Xenios outside the submitted work. The other author 
      declares that he has no conflict of interest related to this manuscript.
EDAT- 2023/02/15 06:00
MHDA- 2023/02/15 06:01
PMCR- 2022/10/04
CRDT- 2023/02/14 01:55
PHST- 2022/05/18 00:00 [received]
PHST- 2022/08/18 00:00 [revised]
PHST- 2022/08/24 00:00 [accepted]
PHST- 2023/02/14 01:55 [entrez]
PHST- 2023/02/15 06:00 [pubmed]
PHST- 2023/02/15 06:01 [medline]
PHST- 2022/10/04 00:00 [pmc-release]
AID - S2667-100X(22)00094-9 [pii]
AID - 10.1016/j.jointm.2022.08.003 [doi]
PST - epublish
SO  - J Intensive Med. 2022 Oct 4;3(1):4-10. doi: 10.1016/j.jointm.2022.08.003. 
      eCollection 2023 Jan 31.