PMID- 36798845
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230505
IS  - 2038-9922 (Print)
IS  - 2038-9930 (Electronic)
IS  - 2038-9922 (Linking)
VI  - 14
IP  - 1
DP  - 2023 Jan 27
TI  - Body composition of type 2 diabetes patients in Uganda: A case-control study.
PG  - 2249
LID - 10.4081/jphia.2023.2249 [doi]
LID - 2249
AB  - INTRODUCTION: The prevalence of obesity among people diagnosed with Type 2 
      Diabetes Mellitus (T2DM) has been widely documented. However, the specific 
      composition of this bodyweight remains largely unknown. The study aimed to 
      understand the body composition of T2DM patients using the bioelectric impedance 
      analysis technique, comparing findings to sex and agematched controls. MATERIALS 
      AND METHODS: A comparative case-control study was carried out among 139 known 
      cases of Type 2 diabetes aged 18 to 78 years randomly sampled from the diabetic 
      clinic of Mbarara Regional Referral Hospital. We matched them to 139 hospital 
      controls who were healthy non-diabetic attendants. Body composition parameters 
      were computed and summarized as medians and interquartile ranges. Differences in 
      the medians of body composition parameters were further assessed using the Mann- 
      Whitney U test. Fat-free and fat mass indices were derived to offer a precise 
      estimation of body composition parameters adjusted for height differences among 
      study participants. RESULTS: Cases had significantly higher median systolic blood 
      pressure, pulse rate, weight, Body Mass Index (BMI), Waist-Hip Ratio (WHR), total 
      fat percentage, fat mass amount, Fat Mass Index, visceral fat, and metabolic age 
      than their counterparts, whereas controls had significantly higher median total 
      body water percentage versus cases. The highest significant differences occurred 
      in fat percentage composition (Cases: beta: 6.9 (95% C.I: 4.4, 9.4); Controls: Ref) 
      followed by visceral fat (Cases: beta: 3.5 (95% C.I: 2.5, 4.4); controls: Ref) and 
      Fat Mass Index (Cases: 95% C.I: 2.6 (95% C.I: 1.6, 3.7). Cases had significantly 
      higher Fat Mass Index, visceral fat and fat percentage (all p<0.05) than 
      controls. CONCLUSIONS: Routine assessment of body composition of T2DM patients 
      needs to be done to assess the amount, type and pattern of weight gain to prevent 
      increases in adiposity.
CI  - (c)Copyright: the Author(s).
FAU - Buyinza, Ronald
AU  - Buyinza R
AD  - Pharmacy Department, Mbarara Regional Referral Hospital, Mbarara, Uganda.
FAU - Nsamba, Jonathan
AU  - Nsamba J
AD  - Department of Clinical Research, Jeuticals Research and Consulting (U) Ltd., 
      Kampala, Uganda.
AD  - Department of Public Health and Community Medicine, Central University of Kerala, 
      Periya, India.
FAU - Muyingo, Anthony
AU  - Muyingo A
AD  - Diabetes Clinic, Mbarara Regional Referral Hospital, Mbarara, Uganda.
FAU - Matovu, Nicholas
AU  - Matovu N
AD  - Department of Community Health and Behavioural Sciences, School of Public Health, 
      Makerere University, Kampala, Uganda.
AD  - Centre for Public Health, Queens University Belfast, Belfast, United Kingdom.
FAU - Nabirye, Gloria
AU  - Nabirye G
AD  - Department of Nursing, Faculty of Health Sciences, Busitema University, Busitema, 
      Uganda.
FAU - Kantengwa, Adellah
AU  - Kantengwa A
AD  - Diabetes Clinic, Mbarara Regional Referral Hospital, Mbarara, Uganda.
FAU - Akandunda, Sandra
AU  - Akandunda S
AD  - Diabetes Clinic, Mbarara Regional Referral Hospital, Mbarara, Uganda.
FAU - Sseguya, Wenceslaus
AU  - Sseguya W
AD  - Diabetes Clinic, St. Francis Nsambya Hospital, Kampala, Uganda.
FAU - Mathews, Elezebeth
AU  - Mathews E
AD  - Department of Public Health and Community Medicine, Central University of Kerala, 
      Periya, India.
LA  - eng
GR  - IA/CPHE/17/1/503345/WTDBT_/DBT-Wellcome Trust India Alliance/India
PT  - Journal Article
DEP - 20230201
PL  - Italy
TA  - J Public Health Afr
JT  - Journal of public health in Africa
JID - 101586943
PMC - PMC9926559
COIS- Conflict of interest: The authors declare no potential conflict of interest. 
      Funding: This study was supported by a capacity building research grant extended 
      through Mbarara Regional Referral Hospital and Mbarara University of Science and 
      Technology 2020 by Hansjoerg Wyss and Massachusetts General Hospital.
EDAT- 2023/02/18 06:00
MHDA- 2023/02/18 06:01
PMCR- 2023/02/01
CRDT- 2023/02/17 02:16
PHST- 2022/06/04 00:00 [received]
PHST- 2022/06/28 00:00 [accepted]
PHST- 2023/02/17 02:16 [entrez]
PHST- 2023/02/18 06:00 [pubmed]
PHST- 2023/02/18 06:01 [medline]
PHST- 2023/02/01 00:00 [pmc-release]
AID - 10.4081/jphia.2023.2249 [doi]
PST - epublish
SO  - J Public Health Afr. 2023 Feb 1;14(1):2249. doi: 10.4081/jphia.2023.2249. 
      eCollection 2023 Jan 27.