PMID- 36803532 OWN - NLM STAT- MEDLINE DCOM- 20230223 LR - 20230224 IS - 1749-8090 (Electronic) IS - 1749-8090 (Linking) VI - 18 IP - 1 DP - 2023 Feb 17 TI - Tricuspid repair in mitral regurgitation surgery: a systematic review and meta-analysis. PG - 76 LID - 10.1186/s13019-023-02158-9 [doi] LID - 76 AB - BACKGROUND: Concomitant tricuspid repair in MR surgery is indicated in patients with severa tricuspid regurgitation, however, concomitant repair in less-than-severe TR patients is still a matter of debate. METHODS: In December 2021, we systematically searched PubMed, Embase and Cochrane databases for randomised control trials (RCTs) comparing isolated MR surgery versus MR surgery with concomitant TR annuloplasty. Four studies were included, resulting in 651 patients (323 in the prophylactic tricuspid intervention group and 328 in the no tricuspid intervention group). RESULTS: Our meta-analysis showed a similar all-cause mortality and perioperative mortality for concomitant prophylactic tricuspid repair when compared with no tricuspid intervention (pooled odds ratio (OR), 0.54; 95% confidence interval (CI): 0.25-1.15, P = 0.11; I(2) = 0% and pooled OR, 0.54; 95% CI: 0.25-1.15, P = 0.11; I(2) = 0%, respectively) in patients undergoing MV surgery. despite a significantly lower TR progression (pooled OR, 0.06; 95% CI: 0.02-0.24, P < 0.01; I(2) = 0%). Additionally, similar New York Heart Association (NYHA) classes III and IV were identified in both concomitant prophylactic tricuspid repair and no tricuspid intervention, despite a lower trend in the tricuspid intervention group (pooled OR, 0.63; 95% CI: 0.38-1.06, P = 0.08; I(2) = 0%). CONCLUSIONS: Our pooled analyses suggested that TV repair at the time of MV surgery in patients with moderate or less-than-moderate TR did not impact on perioperative or postoperative all-cause mortality, despite reducing TR severity and TR progression following the intervention. CI - (c) 2023. The Author(s). FAU - Cardoso, Joao Lopes AU - Cardoso JL AD - Servico de Cardiotoracica, Centro Hospitalar Vila Nova de Gaia/Espinho, Rua Conceicao Fernandes, 4434-502, Vila Nova de Gaia, Portugal. joaoluisflcardoso@gmail.com. FAU - Ferraz Costa, Goncalo Nuno AU - Ferraz Costa GN AD - Servico de Cardiologia, Centro Hospitalar E Universitario de Coimbra, Coimbra, Portugal. FAU - Neves, Fatima AU - Neves F AD - Servico de Cardiotoracica, Centro Hospitalar Vila Nova de Gaia/Espinho, Rua Conceicao Fernandes, 4434-502, Vila Nova de Gaia, Portugal. FAU - Goncalves, Lino AU - Goncalves L AD - Servico de Cardiologia, Centro Hospitalar E Universitario de Coimbra, Coimbra, Portugal. AD - Faculdade de Medicina da Universidade de Coimbra, Coimbra, Portugal. AD - Coimbra Institute for Clinical and Biomedical Research (iCBR), Coimbra, Portugal. FAU - Teixeira, Rogerio AU - Teixeira R AD - Servico de Cardiologia, Centro Hospitalar E Universitario de Coimbra, Coimbra, Portugal. AD - Faculdade de Medicina da Universidade de Coimbra, Coimbra, Portugal. AD - Coimbra Institute for Clinical and Biomedical Research (iCBR), Coimbra, Portugal. LA - eng PT - Journal Article PT - Meta-Analysis PT - Systematic Review DEP - 20230217 PL - England TA - J Cardiothorac Surg JT - Journal of cardiothoracic surgery JID - 101265113 SB - IM MH - Humans MH - *Mitral Valve Insufficiency/complications MH - *Heart Valve Prosthesis Implantation/methods MH - Treatment Outcome MH - Retrospective Studies MH - Mitral Valve/surgery MH - *Tricuspid Valve Insufficiency/complications PMC - PMC9938557 OTO - NOTNLM OT - Mitral valve OT - Prophylactic tricuspid repair OT - Tricuspid regurgitation OT - Tricuspid valve COIS- None declared. EDAT- 2023/02/22 06:00 MHDA- 2023/02/25 06:00 PMCR- 2023/02/17 CRDT- 2023/02/21 18:08 PHST- 2022/11/20 00:00 [received] PHST- 2023/01/24 00:00 [accepted] PHST- 2023/02/21 18:08 [entrez] PHST- 2023/02/22 06:00 [pubmed] PHST- 2023/02/25 06:00 [medline] PHST- 2023/02/17 00:00 [pmc-release] AID - 10.1186/s13019-023-02158-9 [pii] AID - 2158 [pii] AID - 10.1186/s13019-023-02158-9 [doi] PST - epublish SO - J Cardiothorac Surg. 2023 Feb 17;18(1):76. doi: 10.1186/s13019-023-02158-9.