PMID- 36808956
OWN - NLM
STAT- MEDLINE
DCOM- 20230224
LR  - 20230224
IS  - 2769-755X (Electronic)
IS  - 2769-7541 (Linking)
VI  - 132
IP  - 2
DP  - 2023 Feb
TI  - A thorough investigation of the bifactor model of psychopathology in a 
      representative birth cohort: Testing internal and predictive validity to inform 
      models of comorbidity.
PG  - 123-134
LID - 10.1037/abn0000816 [doi]
AB  - This study used symptom dimensions reflecting DSM-V internalizing, externalizing, 
      eating disorders, and substance use (SU) and related problems to thoroughly 
      investigate the structure of psychopathology in mid-adolescence (15 and 17 years, 
      N = 1,515, 52% female). Compared to other hierarchical configurations 
      (unidimensional, correlated factors, or higher-order model), a bifactor model of 
      psychopathology wherein all first-order symptom dimensions loaded onto a 
      second-order general psychopathology factor (P factor) and one of three, 
      second-order specific internalizing, externalizing, or SU factors, best captured 
      the structure of the psychopathology in mid-adolescence. This bifactor model was 
      then used to predict several distinct mental health disorders and alcohol use 
      disorder (AUD) at 20 years, via a structural equation model (SEM). The P factor 
      (bifactor model) was associated with all but one outcome (suicidal ideation 
      without an attempt), at 20 years. Controlling for the P factor, there were no 
      additional, positive, temporal cross-associations (i.e., between mental health 
      (mid-adolescence) and AUD at 20 years, or between SU (mid-adolescence) and mental 
      health problems at 20 years). These results are bolstered by findings from a 
      well-fitting correlated factors model. Namely, when mid-adolescent 
      psychopathology was modeled using an adjusted correlated factors model, 
      associations with outcomes at 20 years were largely masked, with no significant 
      partial, temporal cross-associations. Thus, collectively, findings indicate that 
      comorbidity between SU and mental health in youth may be largely attributable to 
      an underlying liability to experience both problems (i.e., P factor). Ultimately, 
      results support targeting the common liability to psychopathology in the 
      prevention of later mental health problems and AUD. (PsycInfo Database Record (c) 
      2023 APA, all rights reserved).
FAU - Pocuca, Nina
AU  - Pocuca N
AUID- ORCID: 0000-0003-0264-1680
AD  - University of Montreal.
FAU - Geoffroy, Marie-Claude
AU  - Geoffroy MC
AD  - Douglas Mental Health University Institute.
FAU - Paquin, Stephane
AU  - Paquin S
AUID- ORCID: 0000-0001-9957-5696
AD  - The Pennsylvania State University.
FAU - Archambault, Kim
AU  - Archambault K
AUID- ORCID: 0000-0001-7716-7974
AD  - University of Montreal.
FAU - Seguin, Jean R
AU  - Seguin JR
AUID- ORCID: 0000-0003-3359-6202
AD  - Sainte-Justine Research Center.
FAU - Parent, Sophie
AU  - Parent S
AUID- ORCID: 0000-0003-1259-3539
AD  - University of Montreal.
FAU - Boivin, Michel
AU  - Boivin M
AD  - Laval University.
FAU - Tremblay, Richard E
AU  - Tremblay RE
AD  - Sainte-Justine Research Center.
FAU - Cote, Sylvana
AU  - Cote S
AD  - University of Montreal.
FAU - Castellanos-Ryan, Natalie
AU  - Castellanos-Ryan N
AUID- ORCID: 0000-0002-7077-1340
AD  - University of Montreal.
LA  - eng
GR  - ministere de la Sante et des Services sociaux/
GR  - le ministere de la Famille/
GR  - le ministere de l'Education et de l'Enseignement superieur/
GR  - the Lucie and Andre Chagnon Foundation/
GR  - the Institut de recherche RobertSauve en sante et en securite du travail/
GR  - the Research Centre of the SainteJustine University Hospital/
GR  - the ministere du Travail, de l'Emploi et de la Solidarite sociale/
GR  - Institut de la statistique du Quebec/
GR  - Fonds de Recherche du Quebec-Sante/
GR  - Fonds de Recherche du Quebec-Societe et Culture/
GR  - Social Science and Humanities Research Council of Canada/
GR  - Canadian Institutes of Health Research/
GR  - Canadian Centre on Substance Use and Addiction/
PT  - Journal Article
PL  - United States
TA  - J Psychopathol Clin Sci
JT  - Journal of psychopathology and clinical science
JID - 9918351179206676
SB  - IM
MH  - Adolescent
MH  - Humans
MH  - Female
MH  - Male
MH  - Psychopathology
MH  - Comorbidity
MH  - *Substance-Related Disorders/epidemiology
MH  - *Alcoholism
MH  - *Feeding and Eating Disorders
EDAT- 2023/02/23 06:00
MHDA- 2023/02/25 06:00
CRDT- 2023/02/22 13:26
PHST- 2023/02/22 13:26 [entrez]
PHST- 2023/02/23 06:00 [pubmed]
PHST- 2023/02/25 06:00 [medline]
AID - 2023-47595-001 [pii]
AID - 10.1037/abn0000816 [doi]
PST - ppublish
SO  - J Psychopathol Clin Sci. 2023 Feb;132(2):123-134. doi: 10.1037/abn0000816.