PMID- 36811257
OWN - NLM
STAT- MEDLINE
DCOM- 20230315
LR  - 20230320
IS  - 1097-0347 (Electronic)
IS  - 1043-3074 (Linking)
VI  - 45
IP  - 4
DP  - 2023 Apr
TI  - Swallowing outcomes following division of pseudo-epiglottis resulting from 
      vertical pharyngeal closure in laryngectomy.
PG  - 952-962
LID - 10.1002/hed.27311 [doi]
AB  - BACKGROUND: Vertical closure of the pharynx after laryngectomy can result in an 
      outpouch of the anterior wall of the neopharynx below the tongue base, called a 
      pseudo-diverticulum. The prolapsed mucosa that separates the rest of the 
      neopharynx from the pseudo-diverticulum is termed a pseudo-epiglottis. METHODS: 
      Prospective study of patients with pseudo-epiglottis. M. D. Anderson Dysphagia 
      Inventory (MDADI) scores were used to assess swallowing outcomes pre- and 
      post-pseudo-epiglottis division, including minimally clinically important 
      difference (MCID) assessment. RESULTS: Of 16 patients with a pseudo-epiglottis, 
      12 had dysphagia (75%). Symptomatic patients had significantly worse global MDADI 
      and subscale scores. After division, the mean composite MDADI increased from 48.3 
      to 64.7 (p = 0.035), including a high MCID (16.4) with a similar improvement in 
      the global question rating findings (31.1 vs. 60, p = 0.021). The MCID was 
      significant for all MDADI subscales. CONCLUSIONS: Pseudo-epiglottis formation is 
      associated with significantly worse global and subscale MDADI scores. A 
      clinically- and statistically-significant improvement in the MDADI scores was 
      found following surgical division.
CI  - (c) 2023 Wiley Periodicals LLC.
FAU - Tikka, Theofano
AU  - Tikka T
AUID- ORCID: 0000-0003-2828-2874
AD  - ENT Department, Queen Elizabeth University Hospital, Glasgow, UK.
FAU - Hall, Mark Andrew
AU  - Hall MA
AD  - Radiology Department, Queen Elizabeth University Hospital, Glasgow, UK.
FAU - de Blieck, Sarah Margaret
AU  - de Blieck SM
AD  - Speech and Language Therapy Department, Queen Elizabeth University Hospital, 
      Glasgow, UK.
FAU - Buchanan, Malcolm Alexander
AU  - Buchanan MA
AD  - ENT Department, Queen Elizabeth University Hospital, Glasgow, UK.
LA  - eng
PT  - Journal Article
DEP - 20230221
PL  - United States
TA  - Head Neck
JT  - Head & neck
JID - 8902541
SB  - IM
MH  - Humans
MH  - Deglutition
MH  - *Deglutition Disorders/etiology/surgery
MH  - Pharynx/surgery
MH  - Laryngectomy/adverse effects/methods
MH  - Epiglottis
MH  - Prospective Studies
MH  - *Diverticulum/surgery
MH  - Quality of Life
OTO - NOTNLM
OT  - dysphagia
OT  - laryngectomy
OT  - pseudo-epiglottis
OT  - swallow
OT  - vertical closure
EDAT- 2023/02/23 06:00
MHDA- 2023/03/16 06:00
CRDT- 2023/02/22 15:27
PHST- 2023/01/24 00:00 [revised]
PHST- 2022/06/09 00:00 [received]
PHST- 2023/01/31 00:00 [accepted]
PHST- 2023/02/23 06:00 [pubmed]
PHST- 2023/03/16 06:00 [medline]
PHST- 2023/02/22 15:27 [entrez]
AID - 10.1002/hed.27311 [doi]
PST - ppublish
SO  - Head Neck. 2023 Apr;45(4):952-962. doi: 10.1002/hed.27311. Epub 2023 Feb 21.