PMID- 36817263 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20230224 IS - 1426-3912 (Print) IS - 1644-4124 (Electronic) IS - 1426-3912 (Linking) VI - 47 IP - 3 DP - 2022 TI - Ischemic stroke as a rare complication of wasp venom allergy: two clinical scenarios. PG - 288-291 LID - 10.5114/ceji.2022.119153 [doi] AB - Neurological complications after a single Hymenoptera insect sting are very rare. The authors of this paper describe two instances of cerebral ischemic stroke that occurred immediately after a wasp sting. Two distinct pathomechanisms involved in the cases are put forward. When diagnosing such cases, it is vital to rule out the possibility of an immunoglobulin E (IgE)-dependent reaction of hypersensitivity. However, if sIgE antibodies against wasp venom extract and/or its allergenic components are detected, after hospitalization the patient should be qualified for venom immunotherapy, which is the only efficient method of protection from severe allergic reactions caused by an insect sting. Although the incidence of ischemic stroke in patients stung by insects is very low, it is important to be aware of this complication. This will allow rapid implementation of appropriate diagnostics and treatment. The optimal stroke treatment (thrombolysis or mechanical thrombectomy) in these rare cases has not yet been established. CI - Copyright (c) 2022 Termedia. FAU - Nittner-Marszalska, Marita AU - Nittner-Marszalska M AD - Department of Internal Medicine, Pneumology and Allergology, Wroclaw Medical University, Poland. FAU - Guranski, Konstanty AU - Guranski K AD - Department of Neurology, Wroclaw Medical University, Poland. FAU - Bladowska, Joanna AU - Bladowska J AD - Department of Radiology, Wroclaw Medical University, Poland. FAU - Kopec, Agnieszka AU - Kopec A AD - Department of Internal Medicine, Pneumology and Allergology, Wroclaw Medical University, Poland. FAU - Ejma, Maria AU - Ejma M AD - Department of Neurology, Wroclaw Medical University, Poland. LA - eng PT - Case Reports DEP - 20220906 PL - Poland TA - Cent Eur J Immunol JT - Central-European journal of immunology JID - 9702239 PMC - PMC9896982 OTO - NOTNLM OT - ischemic stroke OT - venom immunotherapy OT - wasp sting OT - wasp venom allergy COIS- The authors declare no conflict of interest. EDAT- 2023/02/24 06:00 MHDA- 2023/02/24 06:01 PMCR- 2022/01/01 CRDT- 2023/02/23 09:33 PHST- 2022/03/17 00:00 [received] PHST- 2022/07/29 00:00 [accepted] PHST- 2023/02/23 09:33 [entrez] PHST- 2023/02/24 06:00 [pubmed] PHST- 2023/02/24 06:01 [medline] PHST- 2022/01/01 00:00 [pmc-release] AID - 47726 [pii] AID - 10.5114/ceji.2022.119153 [doi] PST - ppublish SO - Cent Eur J Immunol. 2022;47(3):288-291. doi: 10.5114/ceji.2022.119153. Epub 2022 Sep 6.