PMID- 36819886 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20230224 IS - 2514-2119 (Electronic) IS - 2514-2119 (Linking) VI - 7 IP - 2 DP - 2023 Feb TI - Retrograde venography to navigate an occluded subclavian vein to achieve cardiac resynchronization therapy upgrade via His bundle pacing: a case report. PG - ytad016 LID - 10.1093/ehjcr/ytad016 [doi] LID - ytad016 AB - BACKGROUND: Guidelines support upgrade to cardiac resynchronization therapy (CRT) through His-bundle pacing (HBP) in pacing-induced cardiomyopathy and moderate left ventricular systolic dysfunction (LVSD). Lead-related venous occlusion can represent an obstacle to upgrade procedures. We describe a technique to overcome venous occlusion through direct puncture of a collateral vein facilitating upgrade to HBP. CASE SUMMARY: An 84-year-old man with a right ventricular (RV) pacemaker was referred with New York Heart Association (NYHA) Class III breathlessness secondary to moderate LVSD (left ventricular ejection fraction [LVEF] 45%). Device interrogation revealed 100% RV pacing and AV-dyssynchrony. To optimize atrioventricular (AV) and interventricular (VV) synchrony a CRT upgrade with HBP was planned. Venography revealed an occluded left subclavian vein which was probed in a retrograde manner using a 6F MPA catheter from right femoral venous access. We were able to direct the catheter distal to the left brachio-cephalic vein and define the occlusion using contrast. A collateral branch was identified, a J-wire was left in this branch and venous access was secured at this medial subclavian site using the Seldinger technique. A right atrial lead was deployed and 69 cm ISI-1 His lead was deployed via a C315 sheath at the His-bundle. The resulted in non-selective HBP (Stim-QRS end 146 ms). There were no procedural complications. Two months later both symptoms and LV function (LVEF 55%) improved. DISCUSSION: Lead-related venous occlusion occurs frequently and can be probed in a retrograde manner from femoral venous access using contrast, facilitating direct percutaneous puncture of collateral venous branches to allow upgrade to CRT via HBP. CI - (c) The Author(s) 2023. Published by Oxford University Press on behalf of the European Society of Cardiology. FAU - Pavitt, Christopher AU - Pavitt C AUID- ORCID: 0000-0001-5067-8248 AD - Sussex Cardiac Centre, Royal Sussex County Hospital, University Hospitals Sussex NHS Foundation Trust, Eastern Road, Brighton BN2 5BE, UK. FAU - Luther, Vishal AU - Luther V AD - Cardiology Department, Hammersmith Hospital, Imperial College NHS Foundation Trust, 72 Du Cane Road, London W12 0HS, UK. FAU - Lefroy, David AU - Lefroy D AD - Cardiology Department, Hammersmith Hospital, Imperial College NHS Foundation Trust, 72 Du Cane Road, London W12 0HS, UK. FAU - Tanner, Mark AU - Tanner M AD - Cardiology Department, Hammersmith Hospital, Imperial College NHS Foundation Trust, 72 Du Cane Road, London W12 0HS, UK. AD - Cardiology Department, St Richard's Hospital, University Hospitals Sussex NHS Foundation Trust, Spitalfield Lane, Chichester PO19 6SE, UK. LA - eng PT - Case Reports DEP - 20230111 PL - England TA - Eur Heart J Case Rep JT - European heart journal. Case reports JID - 101730741 PMC - PMC9927565 OTO - NOTNLM OT - Cardiac resynchronization therapy OT - Case report OT - His-bundle pacing OT - Venous occlusion COIS- Conflict of interest: None declared. EDAT- 2023/02/24 06:00 MHDA- 2023/02/24 06:01 PMCR- 2023/01/11 CRDT- 2023/02/23 10:08 PHST- 2022/05/03 00:00 [received] PHST- 2022/07/13 00:00 [revised] PHST- 2023/01/09 00:00 [accepted] PHST- 2023/02/23 10:08 [entrez] PHST- 2023/02/24 06:00 [pubmed] PHST- 2023/02/24 06:01 [medline] PHST- 2023/01/11 00:00 [pmc-release] AID - ytad016 [pii] AID - 10.1093/ehjcr/ytad016 [doi] PST - epublish SO - Eur Heart J Case Rep. 2023 Jan 11;7(2):ytad016. doi: 10.1093/ehjcr/ytad016. eCollection 2023 Feb.