PMID- 36824219
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230226
IS  - 2296-875X (Print)
IS  - 2296-875X (Electronic)
IS  - 2296-875X (Linking)
VI  - 9
DP  - 2022
TI  - Clinical effect of kyphoplasty in the treatment of osteoporotic thoracolumbar 
      compression fractures in patients with diabetes.
PG  - 1031547
LID - 10.3389/fsurg.2022.1031547 [doi]
LID - 1031547
AB  - OBJECTIVE: To study the clinical effect and influencing factors of kyphoplasty in 
      the treatment of osteoporotic thoracolumbar compression fractures (OTCF) 
      complicated with type 2 diabetes mellitus (T2DM). METHODS: A total of 472 
      patients with OTCF complicated with diabetes who were enrolled in our hospital 
      from January to December 2019 were selected as the study subjects, and all 
      patients were treated with percutaneous kyphoplasty (PKP). The effects of gender, 
      age, smoking, drinking, body mass index (BMI), bone mass density (T score), 
      fasting blood glucose level, fasting C-peptide, glycosylated hemoglobin, course 
      of T2DM, vertebral segment and surgical instrument on postoperative improvement 
      were analyzed. The quality of life was evaluated by visual analog score (VAS) and 
      Oswestry disability index (ODI) before PKP and 7 days, and 6 months after PKP, 
      and the patient satisfaction was assessed by the modified Macnab criteria at 6 
      months postoperatively. RESULTS: The overall excellent and good rate of 
      evaluation result was satisfactory. In multivariate regression, independent risk 
      factors for poor patient satisfaction included: age >/=70 years (odds ratio 
      (OR) = 2.298, 95% confidence interval [CI] 1.290-4.245, P = 0.025), fasting blood 
      glucose >/=8 mmol/L [OR = 2.657, 95%(CI) 1.288-4.121, P = 0.016], glycosylated 
      hemoglobin >/=6.5 mmol/L [OR = 3.438, 95%(CI) 2.543-4.628, P = 0.001], duration >/=8 
      years [OR = 1.732, 95%(CI) 1.471-3.253, P = 0.019] and Kyphon instrument 
      [OR = 1.472, 95%(CI) 1.112-2.228, P = 0.018] were independent influencing factors 
      of OTCF complicated with DM. CONCLUSION: Kyphoplasty for patients with 
      osteoporotic thoracolumbar compression fractures complicated with diabetes can 
      achieve a satisfactory clinical effect, the curative effect is affected by many 
      factors, attention to these factors can improve the clinical effect.
CI  - (c) 2023 Gao, Du, Huang, Li, Hao, He and Yan.
FAU - Gao, Xiangcheng
AU  - Gao X
AD  - Medical College, Yan'an University, Yan'an, China.
AD  - Department of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, 
      China.
FAU - Du, Jinpeng
AU  - Du J
AD  - Department of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, 
      China.
FAU - Huang, Yunfei
AU  - Huang Y
AD  - Department of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, 
      China.
FAU - Li, Shuai
AU  - Li S
AD  - Department of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, 
      China.
FAU - Hao, Dingjun
AU  - Hao D
AD  - Department of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, 
      China.
FAU - He, Baorong
AU  - He B
AD  - Department of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, 
      China.
FAU - Yan, Liang
AU  - Yan L
AD  - Department of Spine Surgery, Honghui Hospital, Xi'an Jiaotong University, Xi'an, 
      China.
LA  - eng
PT  - Journal Article
DEP - 20230207
PL  - Switzerland
TA  - Front Surg
JT  - Frontiers in surgery
JID - 101645127
PMC - PMC9941632
OTO - NOTNLM
OT  - clinical effect
OT  - diabetes
OT  - kyphoplasty
OT  - risk facors
OT  - thoracolumbar fracture
COIS- The authors declare that the research was conducted in the absence of any 
      commercial or financial relationships that could be construed as a potential 
      conflict of interest.
EDAT- 2023/02/25 06:00
MHDA- 2023/02/25 06:01
PMCR- 2023/02/07
CRDT- 2023/02/24 02:31
PHST- 2022/08/30 00:00 [received]
PHST- 2022/12/22 00:00 [accepted]
PHST- 2023/02/24 02:31 [entrez]
PHST- 2023/02/25 06:00 [pubmed]
PHST- 2023/02/25 06:01 [medline]
PHST- 2023/02/07 00:00 [pmc-release]
AID - 10.3389/fsurg.2022.1031547 [doi]
PST - epublish
SO  - Front Surg. 2023 Feb 7;9:1031547. doi: 10.3389/fsurg.2022.1031547. eCollection 
      2022.