PMID- 36827015
OWN - NLM
STAT- MEDLINE
DCOM- 20230228
LR  - 20230228
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Linking)
VI  - 102
IP  - 8
DP  - 2023 Feb 22
TI  - Effects of thoracic paravertebral nerve block on postoperative pain and 
      postoperative delirium in elderly patients undergoing thoracoscopic lobectomy.
PG  - e32907
LID - 10.1097/MD.0000000000032907 [doi]
AB  - OBJECTIVES: To evaluate the effects of ultrasound-guided thoracic paravertebral 
      nerve block on perioperative pain and postoperative delirium in elderly patients 
      undergoing thoracoscopic lobotomy. METHODS: Patients aged 60 to 80 years who 
      underwent the surgery of thoracoscopic lobectomy were selected; ASA grades I to 
      III and New York Heart Association (NYHA) grades I to II. Patients were randomly 
      divided into two groups: group C (group Compaired) and group T (group Thoracic 
      Paravertebral Nerve Block TPVB). Patients in group T received ultrason-guided 
      TPVB while those in group C didn't received TPVB. Postoperative 
      patient-controlled intravenous analgesia was administered to all the patients. 
      The consumption of intraoperative opioids, cases of hipoxemia, operative time, 
      and extubation time was also recorded. Pain scores (static and dynamic) were 
      assessed at 2, 4, 6, 24, 48, 72, 96, and 120 hours point after the operation. 
      Pain scores, occurrence of postoperative delirium occurrence, postoperative 
      complications, total amount of analgesic drugs, length of hospital stay, rescue 
      analgesic requirement, and side effects were recorded within 5 days. RESULTS: 
      Intraoperative dosages of sufentanil and remifentanil were significantly lower in 
      group T (Table 1). The postoperative recovery time in group T was significantly 
      shortened (Table 1). The VAS pain scores of group T at 2, 4, 6, and 24 hours 
      after surgery were much lower. The consumption of intraoperative opioids, number 
      of rescue analgesic requirements, and the occurrence of postoperative delirium 
      incidence in group T was significantly reduced (Table 2). There were no 
      differences in hipoxemia events, postoperative nausea, vomiting and pulmonary 
      complications between the two groups (Table 2). CONCLUSION: Preoperative 
      ultrasound-guided thoracic paravertebral nerve block (TPVB) can obviously 
      decrease the intraoperative and postoperative opioids consumption, shorten the 
      recovery time, reduce the number of rescue analgesia and the incidence of 
      postoperative delirium in elderly patients undergoing thoracoscopic lobotomy.
CI  - Copyright (c) 2023 the Author(s). Published by Wolters Kluwer Health, Inc.
FAU - Dongjie, Qiu
AU  - Dongjie Q
AD  - Department of Anesthesiology, The Fourth Hospital of Hebei Medical University, 
      Shijiazhuang, PR China.
FAU - Longbiao, Zhao
AU  - Longbiao Z
AUID- ORCID: 0000-0002-7964-9720
AD  - Department of Anesthesiology, The Third Hospital of Hebei Medical University, 
      Shijiazhuang, PR China.
FAU - Peng, Liu
AU  - Peng L
AD  - Department of Anesthesiology, The Third Hospital of Hebei Medical University, 
      Shijiazhuang, PR China.
FAU - Li, Jia
AU  - Li J
AD  - Department of Anesthesiology, The Fourth Hospital of Hebei Medical University, 
      Shijiazhuang, PR China.
FAU - Hongmeng, Xu
AU  - Hongmeng X
AD  - Department of Anesthesiology, The Fourth Hospital of Hebei Medical University, 
      Shijiazhuang, PR China.
FAU - Zhiyan, Chang
AU  - Zhiyan C
AD  - Department of Anesthesiology, The Fourth Hospital of Hebei Medical University, 
      Shijiazhuang, PR China.
FAU - Long, Yu
AU  - Long Y
AD  - Department of Anesthesiology, The Fourth Hospital of Hebei Medical University, 
      Shijiazhuang, PR China.
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
RN  - 0 (Analgesics)
RN  - 0 (Analgesics, Opioid)
SB  - IM
MH  - Aged
MH  - Humans
MH  - *Nerve Block
MH  - *Emergence Delirium/drug therapy
MH  - *Psychosurgery
MH  - Thoracic Surgery, Video-Assisted
MH  - Pain, Postoperative/drug therapy
MH  - Analgesics/therapeutic use
MH  - Analgesics, Opioid
MH  - Analgesia, Patient-Controlled
COIS- The authors have no conflicts of interest to disclose.
EDAT- 2023/02/25 06:00
MHDA- 2023/03/03 06:00
CRDT- 2023/02/24 12:03
PHST- 2023/02/24 12:03 [entrez]
PHST- 2023/02/25 06:00 [pubmed]
PHST- 2023/03/03 06:00 [medline]
AID - 00005792-202302220-00015 [pii]
AID - 10.1097/MD.0000000000032907 [doi]
PST - ppublish
SO  - Medicine (Baltimore). 2023 Feb 22;102(8):e32907. doi: 
      10.1097/MD.0000000000032907.