PMID- 36842395 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20230317 IS - 2210-2612 (Print) IS - 2210-2612 (Electronic) IS - 2210-2612 (Linking) VI - 104 DP - 2023 Mar TI - Case report: Autopericardial aortic valve replacement and mitral homograft implantation in a patient with ankylosing spondylitis. PG - 107911 LID - S2210-2612(23)00039-1 [pii] LID - 10.1016/j.ijscr.2023.107911 [doi] LID - 107911 AB - INTRODUCTION AND IMPORTANCE: Bekhterev's disease, or ankylosing spondylitis (AS), is a chronic inflammatory rheumatic disease closely related to the human leukocyte antigen (HLA)-B27. Cardiac damage in AS occurs in 2-10 % of patients more commonly as aortic insufficiency, aortitis, mitral valve fibrosis, or cardiac conduction abnormalities. CASE PRESENTATION: In this article we present a clinical case of a 52-year-old female patient with Bekhterev's disease, who underwent aortic valve reconstruction with autopericardium and mitral homograft implantation in mitral position. CLINICAL DISCUSSION: The use of homografts and reconstructive surgeries using autologous materials allow not only avoiding lifelong intake of anticoagulants, but also maintaining hemodynamic profile comparable to that of native valves. CONCLUSION: This clinical case shows that treatment of patients with rheumatic diseases is a complex treatment problem that requires a personalized approach. CI - Copyright (c) 2023 The Authors. Published by Elsevier Ltd.. All rights reserved. FAU - Komarov, R N AU - Komarov RN AD - Department of Cardiovascular Surgery, I. M. Sechenov University Hospital, First Moscow State Medical University, Trubetskaya str., d 8, str.2, Moscow 119991, Russia. FAU - Tkachev, M I AU - Tkachev MI AD - Department of Cardiovascular Surgery, I. M. Sechenov University Hospital, First Moscow State Medical University, Trubetskaya str., d 8, str.2, Moscow 119991, Russia. Electronic address: tkachev.cardiovascular@gmail.com. FAU - Ismailbaev, A M AU - Ismailbaev AM AD - Department of Cardiovascular Surgery, I. M. Sechenov University Hospital, First Moscow State Medical University, Trubetskaya str., d 8, str.2, Moscow 119991, Russia. FAU - Nuzhdin, M D AU - Nuzhdin MD AD - Department of Cardiovascular Surgery, State Budget Healthcare Institution Chelyabinsk Regional Clinical Hospital, Vorovskogo str., d. 70, Chelyabinsk, Chelyabinsk region 454048, Russia. FAU - Savina, V A AU - Savina VA AD - Department of Cardiovascular Surgery, I. M. Sechenov University Hospital, First Moscow State Medical University, Trubetskaya str., d 8, str.2, Moscow 119991, Russia. FAU - Botashev, A A AU - Botashev AA AD - Department of Cardiovascular Surgery, Petrovsky Russian Scientific Center of Surgery, Abrikosovsky per., d.2, Moscow 119435, Russia. LA - eng PT - Case Reports DEP - 20230201 PL - Netherlands TA - Int J Surg Case Rep JT - International journal of surgery case reports JID - 101529872 PMC - PMC9988661 OTO - NOTNLM OT - Ankylosing spondylitis OT - Autopericardial replacement OT - Case report OT - Mitral homograft OT - Neocuspidization COIS- Declaration of competing interest The authors have no conflicts of interest to declare. EDAT- 2023/02/27 06:00 MHDA- 2023/02/27 06:01 PMCR- 2023/02/01 CRDT- 2023/02/26 18:34 PHST- 2022/12/12 00:00 [received] PHST- 2023/01/30 00:00 [accepted] PHST- 2023/02/27 06:00 [pubmed] PHST- 2023/02/27 06:01 [medline] PHST- 2023/02/26 18:34 [entrez] PHST- 2023/02/01 00:00 [pmc-release] AID - S2210-2612(23)00039-1 [pii] AID - 107911 [pii] AID - 10.1016/j.ijscr.2023.107911 [doi] PST - ppublish SO - Int J Surg Case Rep. 2023 Mar;104:107911. doi: 10.1016/j.ijscr.2023.107911. Epub 2023 Feb 1.