PMID- 36849318 OWN - NLM STAT- MEDLINE DCOM- 20230517 LR - 20230517 IS - 1590-3729 (Electronic) IS - 0939-4753 (Linking) VI - 33 IP - 6 DP - 2023 Jun TI - The association between meat intake and the risk of coronary heart disease in Korean men using the Framingham risk score: A prospective cohort study. PG - 1158-1166 LID - S0939-4753(23)00058-3 [pii] LID - 10.1016/j.numecd.2023.02.001 [doi] AB - BACKGROUND AND AIMS: Research suggests that meat intake may increase the risk of coronary heart disease (CHD), but most studies take place in Western countries, where the types and amount of meat products consumed differ from those in Asian countries. We aimed to identify the association between meat intake and CHD risk in Korean male adults, using the Framingham risk score. METHODS AND RESULTS: We used data from the Korean Genome and Epidemiology Study (KoGES) Health Examinees (HEXA) study, including 13,293 Korean male adults. We estimated the association of meat intake with >/=20% 10-year CHD risk using Cox proportional hazards regression models to calculate the hazard ratios (HRs) and 95% confidence intervals (CIs). Subjects with the highest total meat intake had a 53% (model 4: HR 1.53, 95% CI 1.05-2.21) increased 10-year CHD risk compared to those with the lowest intake. Those with the highest red meat intake had a 55% (model 3: HR 1.55, 95% CI 1.16-2.06) increased 10-year CHD risk compared to those with the lowest intake. No association was observed between poultry or processed meat intake and 10-year CHD risk. CONCLUSIONS: Consumption of total meat and red meat was associated with a higher risk of CHD in Korean male adults. Further studies are needed to provide criteria for the appropriate meat intake by meat type to reduce CHD risk. CI - Copyright (c) 2023 The Italian Diabetes Society, the Italian Society for the Study of Atherosclerosis, the Italian Society of Human Nutrition and the Department of Clinical Medicine and Surgery, Federico II University. Published by Elsevier B.V. All rights reserved. FAU - Jeong, Jiwon AU - Jeong J AD - Department of Food and Nutrition, Chung-Ang University, Gyeonggi-do 17546, Republic of Korea. FAU - Lim, Kyungjoon AU - Lim K AD - Faculty of Medicine and Health, School of Medical Sciences, The University of Sydney, Camperdown, NSW, 2006, Australia. FAU - Shin, Sangah AU - Shin S AD - Department of Food and Nutrition, Chung-Ang University, Gyeonggi-do 17546, Republic of Korea. Electronic address: ivory8320@cau.ac.kr. LA - eng PT - Journal Article PT - Research Support, Non-U.S. Gov't DEP - 20230210 PL - Netherlands TA - Nutr Metab Cardiovasc Dis JT - Nutrition, metabolism, and cardiovascular diseases : NMCD JID - 9111474 SB - IM MH - Adult MH - Humans MH - Male MH - Diet/adverse effects MH - Prospective Studies MH - Risk Factors MH - Meat/adverse effects MH - *Red Meat/adverse effects MH - *Coronary Disease/diagnosis/epidemiology/prevention & control MH - Republic of Korea/epidemiology MH - Proportional Hazards Models OTO - NOTNLM OT - Coronary heart disease OT - Fat content OT - HEXA OT - Meat COIS- Declaration of competing interest The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. EDAT- 2023/02/28 06:00 MHDA- 2023/05/17 06:42 CRDT- 2023/02/27 22:04 PHST- 2022/09/01 00:00 [received] PHST- 2023/01/31 00:00 [revised] PHST- 2023/02/03 00:00 [accepted] PHST- 2023/05/17 06:42 [medline] PHST- 2023/02/28 06:00 [pubmed] PHST- 2023/02/27 22:04 [entrez] AID - S0939-4753(23)00058-3 [pii] AID - 10.1016/j.numecd.2023.02.001 [doi] PST - ppublish SO - Nutr Metab Cardiovasc Dis. 2023 Jun;33(6):1158-1166. doi: 10.1016/j.numecd.2023.02.001. Epub 2023 Feb 10.