PMID- 36849921
OWN - NLM
STAT- MEDLINE
DCOM- 20230307
LR  - 20230313
IS  - 2731-4553 (Electronic)
IS  - 2731-4553 (Linking)
VI  - 24
IP  - 1
DP  - 2023 Feb 27
TI  - Factors associated with diabetes-related distress among Asian patients with 
      poorly controlled type-2 diabetes mellitus: a cross-sectional study in primary 
      care.
PG  - 54
LID - 10.1186/s12875-023-02012-w [doi]
LID - 54
AB  - BACKGROUND: Diabetes-related distress (DRD) is a negative emotional state related 
      to the burden of living with diabetes mellitus. It has been associated with poor 
      self-care and glycaemic control. This cross-sectional study aimed to examine the 
      factors associated with DRD among urban Asian patients with poorly controlled 
      type-2 diabetes mellitus (T2DM) in primary care in Singapore. The factors 
      included demographics, diabetes history, medical co-morbidities, mood disorders 
      and social history. METHODS: Patients with T2DM and HbA1c of 8% or more were 
      recruited from 2 public primary care centres in Singapore. They were administered 
      a questionnaire survey to identify DRD based on the Problem Area In Diabetes 
      (PAID) scale. Their anxiety and depression were screened using GAD-7 and PHQ-9, 
      and quality of life (QOL) measured using the EQ-5D-5L. Their clinical data, 
      including HbA1c, comorbidities and medications, were extracted from the 
      electronic medical records. RESULTS: Among the 356 subjects, the prevalence of 
      DRD was 17.4%. DRD was significantly associated with younger age (AOR (95% 
      CI) = 0.93 (0.89-0.97), p = 0.001), ex-smoker status (AOR (95% CI) = 22.30 
      (2.43-204.71), p = 0.006) and history of kidney disease (AOR (95% CI) = 3.41 
      (1.39-8.35), p = 0.007). Those who screened positive for depression (AOR (95% 
      CI) = 4.98 (1.19-20.86), p = 0.028) were almost five times more likely to have 
      DRD. Quality of life was lower among those with DRD (EQ5D index score AOR (95% 
      CI) = 0.11 (0.01-0.97), p = 0.047), who also tended to feel that diabetes 
      pharmacotherapy interfered with their normal life (AOR (95% CI) = 2.89 
      (1.38-6.08), p = 0.005). CONCLUSION: About 1 in 6 patients with poorly controlled 
      T2DM had DRD. Younger age, ex-smoker status, history of kidney disease, and those 
      with depressive symptoms were most at risk.
CI  - (c) 2023. The Author(s).
FAU - Guo, Xiaoxuan
AU  - Guo X
AD  - SingHealth Polyclinics, 167 Jalan Bukit Merah, Connection One, Tower 5, #15-10, 
      Singapore, 150167, Singapore. guo.xiaoxuan@singhealth.com.sg.
AD  - SingHealth-Duke NUS Family Medicine Academic Clinical Programme, 167 Jalan Bukit 
      Merah, Connection One, Tower 5, #15-10, Singapore, 150167, Singapore. 
      guo.xiaoxuan@singhealth.com.sg.
FAU - Wong, Pang Nee Frida
AU  - Wong PNF
AD  - SingHealth Polyclinics, 167 Jalan Bukit Merah, Connection One, Tower 5, #15-10, 
      Singapore, 150167, Singapore.
FAU - Koh, Yi Ling Eileen
AU  - Koh YLE
AD  - SingHealth Polyclinics, 167 Jalan Bukit Merah, Connection One, Tower 5, #15-10, 
      Singapore, 150167, Singapore.
FAU - Tan, Ngiap Chuan
AU  - Tan NC
AD  - SingHealth Polyclinics, 167 Jalan Bukit Merah, Connection One, Tower 5, #15-10, 
      Singapore, 150167, Singapore.
AD  - SingHealth-Duke NUS Family Medicine Academic Clinical Programme, 167 Jalan Bukit 
      Merah, Connection One, Tower 5, #15-10, Singapore, 150167, Singapore.
LA  - eng
PT  - Journal Article
DEP - 20230227
PL  - England
TA  - BMC Prim Care
JT  - BMC primary care
JID - 9918300889006676
RN  - 0 (Glycated Hemoglobin)
SB  - IM
MH  - Humans
MH  - Cross-Sectional Studies
MH  - *Diabetes Mellitus, Type 2/complications/epidemiology/psychology
MH  - Glycated Hemoglobin
MH  - Primary Health Care
MH  - Quality of Life
MH  - *Psychological Distress
PMC - PMC9969642
OTO - NOTNLM
OT  - Diabetes-related distress
OT  - Factors
OT  - Primary care
OT  - Type 2 diabetes mellitus
COIS- The authors declare no competing interests.
EDAT- 2023/03/01 06:00
MHDA- 2023/03/03 06:00
PMCR- 2023/02/27
CRDT- 2023/02/28 00:41
PHST- 2022/05/03 00:00 [received]
PHST- 2023/02/20 00:00 [accepted]
PHST- 2023/02/28 00:41 [entrez]
PHST- 2023/03/01 06:00 [pubmed]
PHST- 2023/03/03 06:00 [medline]
PHST- 2023/02/27 00:00 [pmc-release]
AID - 10.1186/s12875-023-02012-w [pii]
AID - 2012 [pii]
AID - 10.1186/s12875-023-02012-w [doi]
PST - epublish
SO  - BMC Prim Care. 2023 Feb 27;24(1):54. doi: 10.1186/s12875-023-02012-w.