PMID- 36858335
OWN - NLM
STAT- MEDLINE
DCOM- 20230315
LR  - 20230329
IS  - 1878-1519 (Electronic)
IS  - 1569-9048 (Linking)
VI  - 311
DP  - 2023 May
TI  - Cardiorespiratory coupling as an early marker of cardiac autonomic dysfunction in 
      type 2 diabetes mellitus patients.
PG  - 104042
LID - S1569-9048(23)00030-7 [pii]
LID - 10.1016/j.resp.2023.104042 [doi]
AB  - The aim of this study was to assess cardiorespiratory coupling (CRC) in type 2 
      diabetes mellitus patients (T2DM) and apparently healthy individuals, in order to 
      test the hypothesis that this method can provide additional knowledge to the 
      information obtained through the heart rate variability (HRV). A cross-sectional 
      study was conducted in T2DM patients(T2DMG=32) and health controls (CON=32). For 
      CRC analysis, the electrocardiogram, arterial pressure, and thoracic respiratory 
      movement were recorded at rest in supine position and during active standing. 
      Beat-to-beat series of heart period and systolic arterial pressure were analyzed 
      with the respiratory movement signal via a traditional non-causal approach, such 
      as squared coherence function. In this sample of T2DM, no differences in HRV were 
      observed when compared to the CON, but the T2DMG showed a reduction in resting 
      CRC. We conclude that in CRC in T2DM, reflected by the squared coherence may 
      already be compromised even before HRV changes.
CI  - Copyright (c) 2023. Published by Elsevier B.V.
FAU - Da Silva, Claudio Donisete
AU  - Da Silva CD
AD  - Cardiopulmonary Physical Therapy Laboratory, Department of Physical Therapy, 
      Federal University of Sao Carlos, Brazil.
FAU - Catai, Aparecida Maria
AU  - Catai AM
AD  - Cardiovascular Physical Therapy Laboratory, Department of Physical Therapy, 
      Federal University of Sao Carlos, Brazil.
FAU - Abreu, Raphael Martins de
AU  - Abreu RM
AD  - LUNEX University, International University of Health, Exercise & Sports S.A. 50, 
      Department of Physiotherapy, Differdange, Luxembourg. 50 Avenue du Parc des 
      Sports, L-4671, Differdange, Luxembourg; LUNEX ASBL Luxembourg Health & Sport 
      Sciences Research Institute, Differdange, Luxembourg. 50 Avenue du Parc des 
      Sports, L-4671, Differdange, Luxembourg.
FAU - Signini, Etore De Favari
AU  - Signini EF
AD  - Cardiovascular Physical Therapy Laboratory, Department of Physical Therapy, 
      Federal University of Sao Carlos, Brazil.
FAU - Galdino, Gabriela Aguiar Mesquita
AU  - Galdino GAM
AD  - Cardiovascular Physical Therapy Laboratory, Department of Physical Therapy, 
      Federal University of Sao Carlos, Brazil.
FAU - Lorevice, Laura
AU  - Lorevice L
AD  - Cardiopulmonary Physical Therapy Laboratory, Department of Physical Therapy, 
      Federal University of Sao Carlos, Brazil.
FAU - Santos, Leticia Menegalli
AU  - Santos LM
AD  - Cardiopulmonary Physical Therapy Laboratory, Department of Physical Therapy, 
      Federal University of Sao Carlos, Brazil.
FAU - Mendes, Renata Goncalves
AU  - Mendes RG
AD  - Cardiopulmonary Physical Therapy Laboratory, Department of Physical Therapy, 
      Federal University of Sao Carlos, Brazil. Electronic address: 
      renatamendes@ufscar.br.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20230227
PL  - Netherlands
TA  - Respir Physiol Neurobiol
JT  - Respiratory physiology & neurobiology
JID - 101140022
SB  - IM
MH  - Humans
MH  - *Diabetes Mellitus, Type 2/complications
MH  - Cross-Sectional Studies
MH  - Heart
MH  - *Heart Diseases
MH  - Autonomic Nervous System
MH  - *Autonomic Nervous System Diseases/diagnosis/etiology
MH  - Heart Rate/physiology
OTO - NOTNLM
OT  - Autonomic nervous system
OT  - Cardiac control
OT  - Heart rate variability
OT  - Type 2 diabetes mellitus
EDAT- 2023/03/02 06:00
MHDA- 2023/03/16 06:00
CRDT- 2023/03/01 19:27
PHST- 2022/11/12 00:00 [received]
PHST- 2023/02/20 00:00 [revised]
PHST- 2023/02/26 00:00 [accepted]
PHST- 2023/03/02 06:00 [pubmed]
PHST- 2023/03/16 06:00 [medline]
PHST- 2023/03/01 19:27 [entrez]
AID - S1569-9048(23)00030-7 [pii]
AID - 10.1016/j.resp.2023.104042 [doi]
PST - ppublish
SO  - Respir Physiol Neurobiol. 2023 May;311:104042. doi: 10.1016/j.resp.2023.104042. 
      Epub 2023 Feb 27.