PMID- 36858383
OWN - NLM
STAT- MEDLINE
DCOM- 20230303
LR  - 20230303
IS  - 0255-2930 (Print)
IS  - 0255-2930 (Linking)
VI  - 43
IP  - 3
DP  - 2023 Mar 12
TI  - [Acupuncture for delayed sleep-wake phase disorder: a randomized controlled 
      trial].
PG  - 245-51
LID - 10.13703/j.0255-2930.20221031-k0002 [doi]
AB  - OBJECTIVE: To observe the clinical effect of acupuncture for delayed sleep-wake 
      phase disorder (DSWPD). METHODS: A total of 84 patients with DSWPD were 
      randomized into an observation group (42 cases, 2 cases dropped off) and a 
      control group (42 cases, 3 cases dropped off). On the basis of sleep hygiene 
      education, acupuncture was applied at Shenmai (BL 62), Zhaohai (KI 6), Hegu (LI 
      4), Taichong (LR 3), Zusanli (ST 36) and Sanyinjiao (SP 6) in the observation 
      group, while placebo acupuncture was applied at the same acupoints in the control 
      group. The treatment lasted for 8 weeks, once every other day, 3 times a week in 
      the 1st to 4th weeks; once every 3 days, 2 times a week in the 5th to 8th weeks. 
      Before and after treatment, the actigraphy (ACT) indexes of objective sleep 
      (total time of stay in bed, total sleep time, sleep efficiency, the number of 
      awakenings and the wake time after falling asleep) and plasma cortisol (CORT) 
      level were observed; before and after treatment and in follow-up of 1, 3 months 
      after treatment, the scores of morningness-eveningness questionnaire (MEQ), 
      insomnia severity index (ISI), fatigue severity scale (FSS) and Epworth 
      sleepiness scale (ESS) were observed in the two groups. RESULTS: Compared before 
      treatment, the total sleep time was prolonged, the sleep efficiency was improved, 
      the number of awakenings was reduced, and the wake time after falling asleep was 
      shortened after treatment in the observation group (P<0.01, P<0.05), and those in 
      the observation group after treatment were superior to the control group (P<0.01, 
      P<0.05). Compared before treatment, the MEQ scores after treatment in both groups 
      and in the follow-up of 1, 3 months after treatment in the observation group were 
      increased (P<0.01), and the MEQ score of each time point after treatment in the 
      observation group was higher than the control group (P<0.01). The scores of ISI, 
      FSS and ESS after treatment, and the scores of ISI、ESS in follow-up of 1, 3 
      months after treatment in the observation group were decreased compared with 
      those before treatment (P<0.01, P<0.05), and in the observation group, the scores 
      of ISI, FSS and ESS of each time point after treatment were lower than those in 
      the control group (P<0.01, P<0.05). After treatment, the plasma CORT level in the 
      observation group was decreased compared with that before treatment and that in 
      the control group (P<0.01, P<0.05). CONCLUSION: Acupuncture can improve the sleep 
      and wake phase of patients with DSWPD, improve sleep quality and daytime 
      function, and its mechanism may be related to the down-regulation of plasma CORT 
      level.
FAU - Yu, Xin-Tong
AU  - Yu XT
AD  - Department of Acupuncture-Moxibustion, Yueyang Hospital of Integrated Traditional 
      Chinese and Western Medicine, Shanghai University of TCM, Shanghai 200437, China.
FAU - Yang, Wen-Jia
AU  - Yang WJ
AD  - Department of Acupuncture-Moxibustion, Yueyang Hospital of Integrated Traditional 
      Chinese and Western Medicine, Shanghai University of TCM, Shanghai 200437, China.
FAU - Zhao, Na
AU  - Zhao N
AD  - Department of Acupuncture-Moxibustion, Yueyang Hospital of Integrated Traditional 
      Chinese and Western Medicine, Shanghai University of TCM, Shanghai 200437, China.
FAU - Liang, Rui-Long
AU  - Liang RL
AD  - Department of Acupuncture-Moxibustion, Yueyang Hospital of Integrated Traditional 
      Chinese and Western Medicine, Shanghai University of TCM, Shanghai 200437, China.
FAU - Sun, Xu-Qiu
AU  - Sun XQ
AD  - Department of Acupuncture-Moxibustion, Yueyang Hospital of Integrated Traditional 
      Chinese and Western Medicine, Shanghai University of TCM, Shanghai 200437, China.
FAU - Bi, Yue-Ping
AU  - Bi YP
AD  - Shanghai Yangpu District Yinhang Community Health Service Center, Shanghai 
      200438.
FAU - Mou, Yan-Yan
AU  - Mou YY
AD  - Shanghai Yangpu District Yinhang Community Health Service Center, Shanghai 
      200438.
LA  - chi
PT  - English Abstract
PT  - Journal Article
PT  - Randomized Controlled Trial
PL  - China
TA  - Zhongguo Zhen Jiu
JT  - Zhongguo zhen jiu = Chinese acupuncture & moxibustion
JID - 8600658
SB  - IM
MH  - Humans
MH  - *Acupuncture Therapy
MH  - Sleep
MH  - Acupuncture Points
MH  - Down-Regulation
MH  - Sleep Duration
OTO - NOTNLM
OT  - acupuncture
OT  - circadian rhythm
OT  - delayed sleep-wake phase disorder
OT  - randomized controlled trial (RCT)
OT  - sleep-wake
EDAT- 2023/03/02 06:00
MHDA- 2023/03/04 06:00
CRDT- 2023/03/01 20:24
PHST- 2023/03/01 20:24 [entrez]
PHST- 2023/03/02 06:00 [pubmed]
PHST- 2023/03/04 06:00 [medline]
AID - 10.13703/j.0255-2930.20221031-k0002 [doi]
PST - ppublish
SO  - Zhongguo Zhen Jiu. 2023 Mar 12;43(3):245-51. doi: 
      10.13703/j.0255-2930.20221031-k0002.