PMID- 36860149
OWN - NLM
STAT- MEDLINE
DCOM- 20230303
LR  - 20230918
IS  - 1827-675X (Electronic)
IS  - 0392-100X (Print)
IS  - 0392-100X (Linking)
VI  - 43
IP  - 1
DP  - 2023 Feb
TI  - Surgical management of chronic rhinosinusitis with nasal polyps under local 
      anaesthesia: indications and results.
PG  - 42-48
LID - 10.14639/0392-100X-N1984 [doi]
AB  - OBJECTIVE: Our objective was to specify the indications and duration of 
      effectiveness of Awake Patient Polyp Surgery (APPS) in Chronic Rhinosinusitis 
      with Nasal Polyps (CRSwNP). Secondary objectives were to evaluate complications 
      and Patient-Reported Experience (PREMs) and Outcome Measures (PROMs). METHODS: We 
      collected information regarding sex, age, comorbidities and treatments. Duration 
      of effectiveness was the duration of non-recurrence defined by the time between 
      APPS and a new treatment. Nasal Polyp Score (NPS) and Visual Analogic Scales 
      (VAS, from 0/10 to 10/10) for nasal obstruction and olfactory disorders were 
      assessed preoperatively and one month after surgery. PREMs were evaluated using a 
      new tool: the APPS score. RESULTS: Seventy-five patients were enrolled (SR = 3.1, 
      mean age = 60.9 +/- 12.3 years). 60% of patients had a previous history of sinus 
      surgery, 90% had stage 4 NPS and more than 60% had overuse of systemic 
      corticosteroids. Mean time of non-recurrence was 31.3 +/- 2.3 months. We found a 
      significant improvement (all p < 0.001) for NPS (3.8 +/- 0.4 vs 1.5 +/- 0.6), VAS 
      obstruction (9.5 +/- 1.6 vs 0.9 +/- 1.7) and VAS olfactory disorders (4.9 +/- 0.2 vs 
      3.8 +/- 1.7). Mean APPS score was 46.3 +/- 5.5/50. CONCLUSIONS: APPS is a safe and 
      efficient procedure in the management of CRSwNP.
CI  - Copyright (c) 2023 Societa Italiana di Otorinolaringoiatria e Chirurgia 
      Cervico-Facciale, Rome, Italy.
FAU - Mimari, Clemence
AU  - Mimari C
AD  - Aix-Marseille Univ, APHM, Department of Oto-Rhino-Laryngology and Head and Neck 
      Surgery, La Conception University Hospital, Marseille Cedex, France.
FAU - Radulesco, Thomas
AU  - Radulesco T
AD  - Aix-Marseille Univ, APHM, IUSTI, CNRS, Department of Oto-Rhino-Laryngology and 
      Head and Neck Surgery, La Conception University Hospital, Marseille Cedex, 
      France.
FAU - Penicaud, Martin
AU  - Penicaud M
AD  - Aix-Marseille Univ, APHM, Department of Oto-Rhino-Laryngology and Head and Neck 
      Surgery, La Conception University Hospital, Marseille Cedex, France.
FAU - Dessi, Patrick
AU  - Dessi P
AD  - Aix-Marseille Univ, APHM, Department of Oto-Rhino-Laryngology and Head and Neck 
      Surgery, La Conception University Hospital, Marseille Cedex, France.
FAU - Michel, Justin
AU  - Michel J
AD  - Aix-Marseille Univ, APHM, IUSTI, CNRS, Department of Oto-Rhino-Laryngology and 
      Head and Neck Surgery, La Conception University Hospital, Marseille Cedex, 
      France.
LA  - eng
PT  - Journal Article
PL  - Italy
TA  - Acta Otorhinolaryngol Ital
JT  - Acta otorhinolaryngologica Italica : organo ufficiale della Societa italiana di 
      otorinolaringologia e chirurgia cervico-facciale
JID - 8213019
SB  - IM
MH  - Humans
MH  - Middle Aged
MH  - Aged
MH  - *Nasal Polyps
MH  - Anesthesia, Local
MH  - Chronic Disease
MH  - *Nasal Obstruction
MH  - *Olfaction Disorders
MH  - *Sinusitis
PMC - PMC9978296
OTO - NOTNLM
OT  - endoscopic sinus surgery
OT  - inflammatory nasal disease
OT  - local anesthesia
OT  - nasal polyps
OT  - sinusitis
COIS- The authors declare no conflict of interest.
EDAT- 2023/03/03 06:00
MHDA- 2023/03/04 06:00
PMCR- 2023/02/01
CRDT- 2023/03/02 01:43
PHST- 2022/01/13 00:00 [received]
PHST- 2022/09/19 00:00 [accepted]
PHST- 2023/03/02 01:43 [entrez]
PHST- 2023/03/03 06:00 [pubmed]
PHST- 2023/03/04 06:00 [medline]
PHST- 2023/02/01 00:00 [pmc-release]
AID - 10.14639/0392-100X-N1984 [doi]
PST - ppublish
SO  - Acta Otorhinolaryngol Ital. 2023 Feb;43(1):42-48. doi: 10.14639/0392-100X-N1984.