PMID- 36861065 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20230303 IS - 2352-9067 (Print) IS - 2352-9067 (Electronic) IS - 2352-9067 (Linking) VI - 45 DP - 2023 Apr TI - Temporal electrocardiographic changes in anterior ST elevation myocardial infarction versus the Takotsubo syndrome. PG - 101187 LID - 10.1016/j.ijcha.2023.101187 [doi] LID - 101187 AB - BACKGROUND: Electrocardiography (ECG) on admission is similar in ST elevation myocardial infarction (STEMI) and Takotsubo syndrome (TTS). ECG on admission has been extensively investigated and compared between STEMI and TTS, however, only a few studies have compared temporal ECG. Our aim was to compare ECG in anterior STEMI versus female TTS from admission to day 30. METHODS: Adult patients with anterior STEMI or TTS treated at Sahlgrenska University Hospital (Gothenburg, Sweden) from December 2019 to June 2022 were prospectively enrolled. Baseline characteristics, clinical variables and ECGs from admission to day 30 were analyzed. Using a mixed effects model, we compared temporal ECG between female patients with anterior STEMI or TTS, as well as between female and male patients with anterior STEMI. RESULTS: A total of 101 anterior STEMI patients (31 female, 70 male) and 34 TTS patients (29 female, 5 male) were included. The temporal pattern of T wave inversion was similar between female anterior STEMI and female TTS, as well as between female and male anterior STEMI. ST elevation was more common, whereas QT prolongation was less common, in anterior STEMI compared with TTS. Q wave pathology was more similar between female anterior STEMI and female TTS than between female and male anterior STEMI. CONCLUSIONS: The pattern of T wave inversion and Q wave pathology from admission to day 30 was similar in female patients with anterior STEMI and female patients with TTS. Temporal ECG in female patients with TTS may be interpreted as following a "transient ischemic" pattern. CI - (c) 2023 The Authors. FAU - Zeijlon, Rickard AU - Zeijlon R AD - Department of Cardiology, Sahlgrenska University Hospital/S, Gothenburg, Sweden. AD - Department of Internal Medicine, Sahlgrenska University Hospital/S, Gothenburg, Sweden. AD - Department of Molecular and Clinical Medicine/Wallenberg laboratory, Institute of Medicine, Sahlgrenska Academy/University of Gothenburg, Sweden. FAU - Jha, Sandeep AU - Jha S AD - Department of Cardiology, Sahlgrenska University Hospital/S, Gothenburg, Sweden. AD - Department of Molecular and Clinical Medicine/Wallenberg laboratory, Institute of Medicine, Sahlgrenska Academy/University of Gothenburg, Sweden. FAU - Le, Vina AU - Le V AD - Department of Molecular and Clinical Medicine/Wallenberg laboratory, Institute of Medicine, Sahlgrenska Academy/University of Gothenburg, Sweden. FAU - Chamat, Jasmina AU - Chamat J AD - Department of Cardiology, Sahlgrenska University Hospital/O, Gothenburg, Sweden. AD - Department of Molecular and Clinical Medicine/Wallenberg laboratory, Institute of Medicine, Sahlgrenska Academy/University of Gothenburg, Sweden. FAU - Shekka Espinosa, Aaron AU - Shekka Espinosa A AD - Department of Cardiology, Sahlgrenska University Hospital/S, Gothenburg, Sweden. AD - Department of Molecular and Clinical Medicine/Wallenberg laboratory, Institute of Medicine, Sahlgrenska Academy/University of Gothenburg, Sweden. FAU - Poller, Angela AU - Poller A AD - Department of Cardiology, Sahlgrenska University Hospital/S, Gothenburg, Sweden. AD - Department of Molecular and Clinical Medicine/Wallenberg laboratory, Institute of Medicine, Sahlgrenska Academy/University of Gothenburg, Sweden. FAU - Thorleifsson, Sigurdur AU - Thorleifsson S AD - Department of Cardiology, Sahlgrenska University Hospital/S, Gothenburg, Sweden. AD - Department of Molecular and Clinical Medicine/Wallenberg laboratory, Institute of Medicine, Sahlgrenska Academy/University of Gothenburg, Sweden. FAU - Bobbio, Emanuele AU - Bobbio E AD - Department of Cardiology, Sahlgrenska University Hospital/S, Gothenburg, Sweden. FAU - Mellberg, Tomas AU - Mellberg T AD - Department of Cardiology, Sahlgrenska University Hospital/S, Gothenburg, Sweden. FAU - Pirazzi, Carlo AU - Pirazzi C AD - Department of Cardiology, Sahlgrenska University Hospital/S, Gothenburg, Sweden. FAU - Gudmundsson, Thorsteinn AU - Gudmundsson T AD - Department of Cardiology, Sahlgrenska University Hospital/S, Gothenburg, Sweden. FAU - Martinsson, Andreas AU - Martinsson A AD - Department of Cardiology, Sahlgrenska University Hospital/S, Gothenburg, Sweden. FAU - Angeras, Oskar AU - Angeras O AD - Department of Cardiology, Sahlgrenska University Hospital/S, Gothenburg, Sweden. AD - Department of Molecular and Clinical Medicine/Wallenberg laboratory, Institute of Medicine, Sahlgrenska Academy/University of Gothenburg, Sweden. FAU - Ramunddal, Truls AU - Ramunddal T AD - Department of Cardiology, Sahlgrenska University Hospital/S, Gothenburg, Sweden. AD - Department of Molecular and Clinical Medicine/Wallenberg laboratory, Institute of Medicine, Sahlgrenska Academy/University of Gothenburg, Sweden. FAU - Omerovic, Elmir AU - Omerovic E AD - Department of Cardiology, Sahlgrenska University Hospital/S, Gothenburg, Sweden. AD - Department of Molecular and Clinical Medicine/Wallenberg laboratory, Institute of Medicine, Sahlgrenska Academy/University of Gothenburg, Sweden. FAU - Redfors, Bjorn AU - Redfors B AD - Department of Cardiology, Sahlgrenska University Hospital/S, Gothenburg, Sweden. AD - Department of Molecular and Clinical Medicine/Wallenberg laboratory, Institute of Medicine, Sahlgrenska Academy/University of Gothenburg, Sweden. AD - Clinical Trial Center, Cardiovascular Research Foundation, NY, USA. AD - Department of Cardiology, New York-Presbyterian Hospital/Columbia University Medical Center, New York, USA. LA - eng PT - Journal Article DEP - 20230218 PL - Ireland TA - Int J Cardiol Heart Vasc JT - International journal of cardiology. Heart & vasculature JID - 101649525 PMC - PMC9969279 OTO - NOTNLM OT - Electrocardiography OT - ST elevation myocardial infarction OT - Takotsubo syndrome COIS- The authors declare that they have no known competing financial interests or personal relationships that could have appeared to influence the work reported in this paper. EDAT- 2023/03/03 06:00 MHDA- 2023/03/03 06:01 PMCR- 2023/02/18 CRDT- 2023/03/02 02:18 PHST- 2022/11/25 00:00 [received] PHST- 2023/02/07 00:00 [revised] PHST- 2023/02/12 00:00 [accepted] PHST- 2023/03/02 02:18 [entrez] PHST- 2023/03/03 06:00 [pubmed] PHST- 2023/03/03 06:01 [medline] PHST- 2023/02/18 00:00 [pmc-release] AID - S2352-9067(23)00018-0 [pii] AID - 101187 [pii] AID - 10.1016/j.ijcha.2023.101187 [doi] PST - epublish SO - Int J Cardiol Heart Vasc. 2023 Feb 18;45:101187. doi: 10.1016/j.ijcha.2023.101187. eCollection 2023 Apr.