PMID- 36867899
OWN - NLM
STAT- MEDLINE
DCOM- 20230314
LR  - 20230314
IS  - 1095-8630 (Electronic)
IS  - 0301-4797 (Linking)
VI  - 335
DP  - 2023 Jun 1
TI  - Mechanistic characterization of anaerobic microbial degradation of BTBPE in 
      coastal wetland soils: Implication by compound-specific stable isotope analysis.
PG  - 117622
LID - S0301-4797(23)00410-3 [pii]
LID - 10.1016/j.jenvman.2023.117622 [doi]
AB  - As a novel brominate flame retardants, 1,2-bis(2,4,6-tribromophenoxy)ethane 
      (BTBPE) has been extensively used in various consumer products, and frequently 
      detected in various environmental matrices. However, the microbial degradation of 
      BTBPE remains unclear in the environment. This study comprehensively investigated 
      the anaerobic microbial degradation of BTBPE and therein stable carbon isotope 
      effect in the wetland soils. BTBPE degradation followed the pseudo-first-order 
      kinetic, with degradation rate of 0.0085 +/- 0.0008 day(-1). Based on 
      identification of degradation products, stepwise reductive debromination was the 
      main transformation pathway of BTBPE, and tended to keep the stable of 
      2,4,6-tribromophenoxy group during the microbial degradation. The pronounced 
      carbon isotope fractionation was observed for BTBPE microbial degradation, and 
      carbon isotope enrichment factor (epsilon(C)) was determined to be -4.81 +/- 0.37 per thousand, 
      indicating cleavage of C-Br bond as the rate-limiting step. Compared to 
      previously reported isotope effects, carbon apparent kinetic isotope effect 
      (AKIE(C) = 1.072 +/- 0.004) suggested that the nucleophilic substitution (S(N)2 
      reaction) was the potential reaction mechanism for reductive debromination of 
      BTBPE in the anaerobic microbial degradation. These findings demonstrated that 
      BTBPE could be degraded by the anaerobic microbes in wetland soils, and the 
      compound-specific stable isotope analysis was a robust method to discover the 
      underlying reaction mechanisms.
CI  - Copyright (c) 2023 Elsevier Ltd. All rights reserved.
FAU - Wang, Guoguang
AU  - Wang G
AD  - College of Environmental Science and Engineering, Dalian Maritime University, 
      Dalian, 116026, China. Electronic address: guoguangwang@dlmu.edu.cn.
FAU - Guo, Pengxu
AU  - Guo P
AD  - College of Environmental Science and Engineering, Dalian Maritime University, 
      Dalian, 116026, China.
FAU - Liu, Yu
AU  - Liu Y
AD  - College of Environmental Science and Engineering, Dalian Maritime University, 
      Dalian, 116026, China; Environmental Information Institute, Dalian Maritime 
      University, Dalian, 116026, China.
FAU - Li, Chuanyuan
AU  - Li C
AD  - College of Environmental Science and Engineering, Dalian Maritime University, 
      Dalian, 116026, China.
FAU - Wang, Xu
AU  - Wang X
AD  - College of Environmental Science and Engineering, Dalian Maritime University, 
      Dalian, 116026, China.
FAU - Wang, Haixia
AU  - Wang H
AD  - Navigation College, Dalian Maritime University, Dalian, 116026, China.
LA  - eng
PT  - Journal Article
DEP - 20230301
PL  - England
TA  - J Environ Manage
JT  - Journal of environmental management
JID - 0401664
RN  - 0 (Soil)
RN  - 0 (Carbon Isotopes)
SB  - IM
MH  - *Soil
MH  - Anaerobiosis
MH  - *Wetlands
MH  - Biodegradation, Environmental
MH  - Carbon Isotopes/analysis
OTO - NOTNLM
OT  - 1,2-bis(2,4,6-tribromophenoxy)ethane
OT  - Anaerobic microbial degradation
OT  - Carbon isotope fractionation
OT  - Nucleophilic aromatic substitution
OT  - Reductive debromination
COIS- Declaration of competing interest The authors declare that they have no known 
      competing financial interests or personal relationships that could have appeared 
      to influence the work reported in this paper.
EDAT- 2023/03/04 06:00
MHDA- 2023/03/15 06:00
CRDT- 2023/03/03 18:04
PHST- 2022/12/24 00:00 [received]
PHST- 2023/02/06 00:00 [revised]
PHST- 2023/02/26 00:00 [accepted]
PHST- 2023/03/04 06:00 [pubmed]
PHST- 2023/03/15 06:00 [medline]
PHST- 2023/03/03 18:04 [entrez]
AID - S0301-4797(23)00410-3 [pii]
AID - 10.1016/j.jenvman.2023.117622 [doi]
PST - ppublish
SO  - J Environ Manage. 2023 Jun 1;335:117622. doi: 10.1016/j.jenvman.2023.117622. Epub 
      2023 Mar 1.