PMID- 36875866
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230307
IS  - 1831-4732 (Electronic)
IS  - 1831-4732 (Linking)
VI  - 21
IP  - 3
DP  - 2023 Mar
TI  - Statement on the risk assessment of maximum residue levels (MRLs) for oxamyl in 
      view of consumer protection.
PG  - e07823
LID - 10.2903/j.efsa.2023.7823 [doi]
LID - e07823
AB  - In accordance with Article 43 of Regulation (EC) No 396/2005, the European 
      Commission requested EFSA to perform a risk assessment of the existing maximum 
      residues levels (MRLs) for oxamyl considering the new toxicological reference 
      values. Additionally, if needed to ensure adequate consumer protection, lower 
      limits of quantification (LOQs) than those currently established in the 
      legislation should be proposed. EFSA performed various consumer exposure 
      calculation scenarios, considering the risk assessment values as available for 
      the existing uses of oxamyl and the lowering of LOQs for several plant and animal 
      commodities as suggested by the European Union Reference Laboratories for 
      Pesticide Residues (EURLs). Based on the results of the consumer exposure 
      assessment calculated considering the risk assessment values for crops with 
      authorised oxamyl uses and the existing EU MRLs at the LOQ for remaining 
      commodities (scenario 1), chronic consumer intake concerns were identified for 34 
      diets. Acute exposure concerns were identified for a wide range of crops, 
      including crops with currently authorised oxamyl uses: bananas, potatoes, melons, 
      cucumbers, carrots, watermelons, tomatoes, courgettes, parsnips, salsifies and 
      aubergines/eggplants. Under exposure calculation scenario 3, which considered 
      lowering of all MRLs to the lowest analytically achievable limits of 
      quantification, EFSA concludes that chronic consumer exposure concerns can still 
      not be excluded. Similarly, acute consumer exposure concerns were identified for 
      16 commodities, including crops with known authorised uses: potatoes, melons, 
      watermelons and tomatoes, even though for these crops a lower LOQ as proposed by 
      the EURLs were considered. Further refinements of the calculated exposure at the 
      current stage were not possible by EFSA, but EFSA identified a list of 
      commodities for which a lower LOQ than routinely achievable is expected to 
      significantly reduce the consumer exposure and for which a risk management 
      decision is required.
CI  - (c) 2023 European Food Safety Authority. EFSA Journal published by Wiley-VCH GmbH 
      on behalf of European Food Safety Authority.
CN  - European Food Safety Authority (EFSA)
LA  - eng
PT  - Journal Article
DEP - 20230301
PL  - United States
TA  - EFSA J
JT  - EFSA journal. European Food Safety Authority
JID - 101642076
PMC - PMC9977561
OTO - NOTNLM
OT  - acute and chronic risk assessment
OT  - consumer risk assessment
OT  - limit of quantification
OT  - oxamyl
EDAT- 2023/03/07 06:00
MHDA- 2023/03/07 06:01
PMCR- 2023/03/01
CRDT- 2023/03/06 04:15
PHST- 2023/03/06 04:15 [entrez]
PHST- 2023/03/07 06:00 [pubmed]
PHST- 2023/03/07 06:01 [medline]
PHST- 2023/03/01 00:00 [pmc-release]
AID - EFS27823 [pii]
AID - 10.2903/j.efsa.2023.7823 [doi]
PST - epublish
SO  - EFSA J. 2023 Mar 1;21(3):e07823. doi: 10.2903/j.efsa.2023.7823. eCollection 2023 
      Mar.