PMID- 36881531
OWN - NLM
STAT- MEDLINE
DCOM- 20230412
LR  - 20230412
IS  - 1078-6791 (Print)
IS  - 1078-6791 (Linking)
VI  - 29
IP  - 3
DP  - 2023 Apr
TI  - Value of Group Intervention on Prognosis of Quality of Life in Epileptic Patients 
      Treated With Sodium Valproate and Lamotrigine.
PG  - 193-199
LID - AT8002 [pii]
AB  - OBJECTIVE: The study intended to analyze the effects of a group nursing 
      intervention on quality of life (QoL) of patients with epilepsy (EP) after 
      treatment with sodium valproate combined with lamotrigine. DESIGN: The research 
      team performed a randomized controlled trial. SETTING: The study took place in 
      the Department of Neurology at the Affiliated Brain Hospital of Nanjing Medical 
      University in Nanjing, Jiangsu, China. PARTICIPANTS: Participants were 170 EP 
      patients at the hospital between January 2019 and August 2022. INTERVENTION: The 
      research team randomly assigned participants to one of two groups: (1) 85 to the 
      intervention group, and they took part in a group nursing intervention; and (2) 
      85 to the control group (n = 85) and they received conventional care. OUTCOME 
      MEASURES: To evaluate participants' risk of suicide, psychological state, and 
      QOL, participants completed at baseline and postintervention: (1) the 
      Mini-International Neuropsychiatric Interview (MINI), (2) the Self-Rating Scale 
      for Psychiatric Symptoms 90 (SCL-90), and (3) the Short Form Health Survey 
      (SF-36) To assess participants' management ability, self-efficacy, and social 
      functioning, they also completed at those time points: (1) the EP Self-Management 
      Behavior Scale (ESMS), (2) the General Self-Efficacy Scale (GSES), and (3) the 
      Social Functioning Deficit Screening Scale (SDSS). Finally, the research also 
      investigated participants' satisfaction with the nursing care. RESULTS: The 
      intervention group's risk of suicide decreased between baseline and 
      postintervention, and its SCL-90 scores were significantly lower and SF-36 scores 
      were significantly higher than those of the control group (both P < .05). In 
      addition, the intervention group's ESMS and GSES scores were also significantly 
      higher than those of the control group, while its SDSS score was significantly 
      lower than that of the control group (all P < .05). Finally, the intervention 
      group's nursing satisfaction was also significantly higher than that of the 
      control group (P < .05). CONCLUSIONS: The group nursing intervention can 
      effectively improve the psychological states of EP patients, reduce their pain, 
      improve their self-management skills and QoL, provide them with better and more 
      detailed nursing care, and facilitate the treatment and recovery of EP patients, 
      which can have a significant value in clinical practice.
FAU - Xie, Zhaomin
AU  - Xie Z
FAU - Li, Xuefen
AU  - Li X
FAU - Yin, Junxiong
AU  - Yin J
FAU - Wang, Min
AU  - Wang M
FAU - Fan, Xiaohang
AU  - Fan X
FAU - Yu, Jin
AU  - Yu J
FAU - Wang, Duyanlu
AU  - Wang D
FAU - Li, Yunyi
AU  - Li Y
FAU - Yu, Mengting
AU  - Yu M
LA  - eng
PT  - Journal Article
PT  - Randomized Controlled Trial
PL  - United States
TA  - Altern Ther Health Med
JT  - Alternative therapies in health and medicine
JID - 9502013
RN  - U3H27498KS (Lamotrigine)
RN  - 614OI1Z5WI (Valproic Acid)
SB  - IM
MH  - Humans
MH  - Lamotrigine/therapeutic use
MH  - *Valproic Acid/therapeutic use
MH  - Quality of Life
MH  - Prognosis
MH  - *Epilepsy/drug therapy
EDAT- 2023/03/08 06:00
MHDA- 2023/04/12 06:42
CRDT- 2023/03/07 13:02
PHST- 2023/04/12 06:42 [medline]
PHST- 2023/03/08 06:00 [pubmed]
PHST- 2023/03/07 13:02 [entrez]
AID - AT8002 [pii]
PST - ppublish
SO  - Altern Ther Health Med. 2023 Apr;29(3):193-199.