PMID- 36891480
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230310
IS  - 2168-9709 (Electronic)
IS  - 2168-9709 (Linking)
VI  - 13
IP  - 1
DP  - 2023 Feb
TI  - Post hoc depression analysis from a pharmacist-led diabetes trial.
PG  - 18-24
LID - 10.9740/mhc.2023.02.018 [doi]
AB  - INTRODUCTION: Diabetes and depression may present concurrently, and clinical 
      pharmacists are well equipped to manage these conditions. Clinical pharmacists 
      were grant funded to implement a diabetes-focused randomized controlled trial in 
      a Federally Qualified Health Center. The objective of this analysis is to 
      evaluate if glycemic control and depressive symptoms improve for patients with 
      diabetes and depression with additional management from clinical pharmacists 
      compared with those receiving the standard of care. METHODS: This is a post hoc 
      subgroup analysis of a diabetes-focused randomized controlled trial. Pharmacists 
      enrolled patients with type 2 diabetes mellitus (T2DM) and a glycated hemoglobin 
      (A1C) greater than 8% and randomly assigned them to 1 of 2 cohorts, one managed 
      by the primary care provider alone and one with additional care from the 
      pharmacist. Pharmacists completed encounters with patients who have T2DM with or 
      without depression to comprehensively optimize pharmacotherapy while tracking 
      glycemic and depressive outcomes throughout the study. RESULTS: A1C improved from 
      baseline to 6 months in patients with depressive symptoms who received additional 
      care from pharmacists by -2.4 percentage points (SD, 2.41) compared with a -0.1 
      percentage point (SD, 1.78) reduction in the control arm (P  .0081), and there 
      was no change in depressive symptoms. DISCUSSION: Patients with T2DM and 
      depressive symptoms experienced better diabetes outcomes with additional 
      pharmacist management compared with a similar cohort of patients with depressive 
      symptoms, managed independently by primary care providers. These patients with 
      diabetes and comorbid depression received a higher level of engagement and care 
      from the pharmacists, which led to more therapeutic interventions.
CI  - (c) 2023 AAPP. The Mental Health Clinician is a publication of the American 
      Association of Psychiatric Pharmacists.
FAU - Bateman, M Thomas
AU  - Bateman MT
AUID- ORCID: 0000-0002-2135-6191
AD  - Clinical Assistant Professor, Ernest Mario School of Pharmacy, Rutgers, the State 
      University of New Jersey, Piscataway, New Jersey; and Lead Clinical Pharmacist, 
      Henry J. Austin Health Center, Trenton, New Jersey, mtb163@pharmacy.rutgers.edu.
FAU - McCarthy, Caitlin
AU  - McCarthy C
AUID- ORCID: 0000-0002-8034-051X
AD  - Clinical Assistant Professor, Ernest Mario School of Pharmacy, Rutgers, the State 
      University of New Jersey, Piscataway, New Jersey; and Director of Pharmacy 
      Services, Henry J. Austin Health Center, Trenton, New Jersey.
FAU - Prioli, Katherine M
AU  - Prioli KM
AUID- ORCID: 0000-0003-3987-1738
AD  - Senior Research Analyst, Center for Health Outcomes, Policy, and Economics, 
      Ernest Mario School of Pharmacy, Rutgers, the State University of New Jersey, 
      Piscataway, New Jersey.
FAU - Wagner, Mary L
AU  - Wagner ML
AUID- ORCID: 0000-0002-3441-504X
AD  - Associate Professor, Ernest Mario School of Pharmacy, Rutgers, the State 
      University of New Jersey, Piscataway, New Jersey; and Principal Investigator, 
      Henry J. Austin Health Center, Trenton, New Jersey.
LA  - eng
PT  - Journal Article
DEP - 20230303
PL  - United States
TA  - Ment Health Clin
JT  - The mental health clinician
JID - 101728585
PMC - PMC9987260
OTO - NOTNLM
OT  - Federally Qualified Health Center
OT  - depressive disorder
OT  - interdisciplinary care
OT  - type 2 diabetes mellitus
COIS- Disclosures: The authors have nothing of interest to disclose
EDAT- 2023/03/10 06:00
MHDA- 2023/03/10 06:01
PMCR- 2023/03/03
CRDT- 2023/03/09 02:15
PHST- 2022/08/12 00:00 [received]
PHST- 2023/01/11 00:00 [accepted]
PHST- 2023/03/09 02:15 [entrez]
PHST- 2023/03/10 06:00 [pubmed]
PHST- 2023/03/10 06:01 [medline]
PHST- 2023/03/03 00:00 [pmc-release]
AID - 10.9740/mhc.2023.02.018 [doi]
PST - epublish
SO  - Ment Health Clin. 2023 Mar 3;13(1):18-24. doi: 10.9740/mhc.2023.02.018. 
      eCollection 2023 Feb.