PMID- 36896632 OWN - NLM STAT- MEDLINE DCOM- 20230505 LR - 20230505 IS - 1612-1880 (Electronic) IS - 1612-1872 (Linking) VI - 20 IP - 4 DP - 2023 Apr TI - Preparation, Structural Analysis and Antioxidant Activity of Polysaccharides and Their Derivatives from Pueraria lobata. PG - e202201253 LID - 10.1002/cbdv.202201253 [doi] AB - Pueraria lobata polysaccharides (PLPs) were obtained by hot water extraction using Pueraria lobata as raw material. Structural analysis revealed that PLPs may have a repetitive backbone units of -->4) -alpha-D-Glcp (1-->4-alpha-D-Glcp (1-->. Phosphorylated Pueraria lobata polysaccharides (P-PLPs), carboxymethylated Pueraria lobata polysaccharides (CM-PLPs) and acetylated Pueraria lobata polysaccharides (Ac-PLPs) were obtained by chemical modifications of PLPs, respectively. The physicochemical properties and antioxidant activities of these four Pueraria lobata polysaccharides were studied in comparison. In particular, the clearance rate of P-PLPs exceeded 80 %, and was expected to achieve the same effect as V(c) . The results showed that the effects of different chemical modifications on the antioxidant activity of PLPs varied greatly. CI - (c) 2023 Wiley-VHCA AG, Zurich, Switzerland. FAU - Fan, Yumin AU - Fan Y AD - Key Laboratory of Carbohydrate Science and Engineering, Chongqing Normal University, Chongqing, 401331, China. FAU - Huang, Gangliang AU - Huang G AUID- ORCID: 0000-0001-8768-9979 AD - Key Laboratory of Carbohydrate Science and Engineering, Chongqing Normal University, Chongqing, 401331, China. LA - eng PT - Journal Article DEP - 20230327 PL - Switzerland TA - Chem Biodivers JT - Chemistry & biodiversity JID - 101197449 RN - 0 (Antioxidants) RN - 0 (Plant Extracts) RN - 0 (Polysaccharides) SB - IM MH - Antioxidants/chemistry/pharmacology MH - *Plant Extracts/chemistry MH - Plant Roots/chemistry MH - Polysaccharides/chemistry/pharmacology MH - *Pueraria/chemistry OTO - NOTNLM OT - Pueraria lobata polysaccharide OT - antioxidant activity OT - chemical modification OT - structure EDAT- 2023/03/11 06:00 MHDA- 2023/04/28 06:41 CRDT- 2023/03/10 04:03 PHST- 2022/12/28 00:00 [received] PHST- 2023/03/09 00:00 [accepted] PHST- 2023/04/28 06:41 [medline] PHST- 2023/03/11 06:00 [pubmed] PHST- 2023/03/10 04:03 [entrez] AID - 10.1002/cbdv.202201253 [doi] PST - ppublish SO - Chem Biodivers. 2023 Apr;20(4):e202201253. doi: 10.1002/cbdv.202201253. Epub 2023 Mar 27.