PMID- 36897202
OWN - NLM
STAT- MEDLINE
DCOM- 20230705
LR  - 20230807
IS  - 1557-0584 (Electronic)
IS  - 1557-0576 (Print)
IS  - 1557-0576 (Linking)
VI  - 47
IP  - 3
DP  - 2023 Jul 1
TI  - Reliability, Validity, and Responsiveness of the Patient-Specific Functional 
      Scale for Measuring Mobility-Related Goals in People With Multiple Sclerosis.
PG  - 139-145
LID - 10.1097/NPT.0000000000000439 [doi]
AB  - BACKGROUND AND PURPOSE: This study's purpose was to investigate the reliability, 
      validity, and responsiveness of the Patient-Specific Functional Scale (PSFS) for 
      measuring mobility-related goals in people with multiple sclerosis (MS). METHODS: 
      Data from 32 participants with MS who underwent 8 to 10 weeks of rehabilitation 
      were analyzed (Expanded Disability Status Scale scores 1.0-7.0). For the PSFS, 
      participants identified 3 mobility-related areas where they had difficulty and 
      rated them at baseline, 10 to 14 days later (before starting intervention), and 
      immediately after intervention. Test-retest reliability and response stability of 
      the PSFS were calculated using the intraclass correlation coefficient (ICC 2,1 ) 
      and minimal detectable change (MDC 95 ), respectively. Concurrent validity of the 
      PSFS was determined with the 12-item Multiple Sclerosis Walking Scale (MSWS-12) 
      and the Timed 25-Foot Walk Test (T25FW). PSFS responsiveness was determined using 
      Cohen's d , and minimal clinically important difference (MCID) was calculated 
      based on patient-reported improvements on a Global Rating of Change (GRoC) scale. 
      RESULTS: The PSFS total score demonstrated moderate reliability (ICC 2,1 = 0.70, 
      95% CI: 0.46 to 0.84) and the MDC was 2.1 points. At baseline, the PSFS was 
      fairly and significantly correlated with the MSWS-12 ( r = -0.46, P = 0.008) but 
      not with the T25FW. Changes in the PSFS were moderately and significantly 
      correlated with the GRoC scale (rho = 0.63, P < 0.001), but not with MSWS-12 or 
      T25FW changes. The PSFS was responsive ( d = 1.7), and the MCID was 2.5 points or 
      more to identify patient-perceived improvements based on the GRoC scale 
      (sensitivity = 0.85, specificity = 0.76). DISCUSSION AND CONCLUSIONS: This study 
      supports the use of the PSFS as an outcome measure in people with MS to assess 
      mobility-related goals.Video Abstract available for more insights from the 
      authors (see the Video, Supplemental Digital Content 1, available at: 
      http://links.lww.com/JNPT/A423 ).
CI  - Copyright (c) 2023 Academy of Neurologic Physical Therapy, APTA.
FAU - Manago, Mark M
AU  - Manago MM
AD  - Physical Therapy Program, Department of Physical Medicine and Rehabilitation, 
      University of Colorado, Aurora (M.M.M., C.L.C., M.B.); Department of Neurology, 
      School of Medicine, University of Colorado, Aurora (M.M.M.); Geriatric Research 
      Education and Clinical Center, VA Eastern Colorado Healthcare System, Denver, 
      Colorado (M.M.M., C.L.C., M.B.); Department of Physical Therapy, Arcadia 
      University, Glenside, Pennsylvania (E.T.C.); and Department of Neurology, School 
      of Medicine, Oregon Health & Science University, Portland, and VA Portland Health 
      Care System, Portland, Oregon (M.H.C.).
FAU - Cohen, Evan T
AU  - Cohen ET
FAU - Cameron, Michelle H
AU  - Cameron MH
FAU - Christiansen, Cory L
AU  - Christiansen CL
FAU - Bade, Michael
AU  - Bade M
LA  - eng
SI  - ClinicalTrials.gov/NCT04633759
SI  - ClinicalTrials.gov/NCT04548154
GR  - K12 HD055931/HD/NICHD NIH HHS/United States
GR  - UL1 TR001082/TR/NCATS NIH HHS/United States
GR  - UL1 TR002535/TR/NCATS NIH HHS/United States
PT  - Journal Article
PT  - Research Support, N.I.H., Extramural
PT  - Video-Audio Media
DEP - 20230307
PL  - United States
TA  - J Neurol Phys Ther
JT  - Journal of neurologic physical therapy : JNPT
JID - 101193365
SB  - IM
MH  - Humans
MH  - *Multiple Sclerosis
MH  - Reproducibility of Results
MH  - Goals
MH  - Outcome Assessment, Health Care
MH  - Walk Test
MH  - Disability Evaluation
PMC - PMC10329992
MID - NIHMS1874428
COIS- The authors declare no conflict of interest.
EDAT- 2023/03/11 06:00
MHDA- 2023/07/05 06:42
PMCR- 2024/07/01
CRDT- 2023/03/10 09:53
PHST- 2024/07/01 00:00 [pmc-release]
PHST- 2023/07/05 06:42 [medline]
PHST- 2023/03/11 06:00 [pubmed]
PHST- 2023/03/10 09:53 [entrez]
AID - 01253086-202307000-00002 [pii]
AID - 10.1097/NPT.0000000000000439 [doi]
PST - ppublish
SO  - J Neurol Phys Ther. 2023 Jul 1;47(3):139-145. doi: 10.1097/NPT.0000000000000439. 
      Epub 2023 Mar 7.