PMID- 36898219
OWN - NLM
STAT- MEDLINE
DCOM- 20230501
LR  - 20230501
IS  - 1532-818X (Electronic)
IS  - 0196-0709 (Linking)
VI  - 44
IP  - 3
DP  - 2023 May-Jun
TI  - Preservation versus resection of middle turbinate in endoscopic transnasal 
      transsphenoidal pituitary surgery.
PG  - 103826
LID - S0196-0709(23)00040-6 [pii]
LID - 10.1016/j.amjoto.2023.103826 [doi]
AB  - BACKGROUND: The strategic position of the middle turbinate (MT) within the nasal 
      cavity makes it the first kick start to resect pituitary pathology through 
      Endoscopic Transnasal Transsphenoidal Surgery (ETTS). This research aimed to 
      determine if the type of endonasal endoscopic approach, MT resection (MTres) 
      versus MT preservation (MTpre), for pituitary surgery affects olfaction and 
      sinonasal function within a subjective as well as objective manner. PATIENTS & 
      METHODS: A prospective cohort comparative study was conducted to compare the 
      sinonasal and olfaction outcomes pre and post operatively for both groups. 
      Sinonasal symptoms were evaluated subjectively by Sino-Nasal Outcome Test 
      (SNOT-22), while objectively by Peri-Operative Sinus Endoscope Score (POSE) along 
      with Lund-Mackay radiological scoring system (LMS), and a Sniffin Sticks 
      Identification test (SIT) (Burghart, Germany) was used to measure the olfaction 
      intensity. In both groups were used on a pre-operative period and after one, 
      three, and six months post operatively. RESULTS: 96 patients were recruited 
      within predetermined criteria. It is found that there are no significant 
      differences in SIT between both groups with a rho value 0.439 post operatively. The 
      average change in score (delta) was an increase of 0.3, with changes ranging from 
      -3 to +4. There was no significant difference in sinonasal symptoms score among 
      both groups, with rho 0.07 posts operatively. There was a minor upsurge in POSE 
      score and LMS in the preservation group but without remarkable differences with rho 
      value 0.1 and 0.2 subsequently. It is found that there are no significant 
      differences in SIT between both groups with a rho value 0.439 post operatively. 
      CONCLUSION: Despite these amendments to the nasal cavity, we approved that these 
      changes do not affect the sinonasal functions.
CI  - Copyright (c) 2023 Elsevier Inc. All rights reserved.
FAU - Aziz Baban, Muaid I
AU  - Aziz Baban MI
AD  - Unit of Otorhinolaryngology-Head & Neck Surgery, Department of Surgery, 
      University of Sulaimani, College of Medicine, Sulaymaniyah Teaching Hospital, 
      Sulaymaniyah 46001, Kurdistan, Iraq; Unit of Skull base Surgery, Shar Teaching 
      Hospital, Sulaymaniyah 46001, Kurdistan region, Iraq. Electronic address: 
      muaident@gmail.com.
FAU - Hadi, Sahar J
AU  - Hadi SJ
AD  - Unit of Otorhinolaryngology-Head & Neck Surgery, Department of Surgery, 
      University of Sulaimani, College of Medicine, Sulaymaniyah Teaching Hospital, 
      Sulaymaniyah 46001, Kurdistan, Iraq.
FAU - Mahmoud, Abbas A
AU  - Mahmoud AA
AD  - Unit of Skull base Surgery, Shar Teaching Hospital, Sulaymaniyah 46001, Kurdistan 
      region, Iraq; Unit of Neurosurgery, Shar Teaching Hospital, Sulaymaniyah 46001, 
      Kurdistan region, Iraq.
FAU - Shareef, Deman J
AU  - Shareef DJ
AD  - Unit of Otorhinolaryngology-Head & Neck Surgery, Department of Surgery, 
      University of Sulaimani, College of Medicine, Sulaymaniyah Teaching Hospital, 
      Sulaymaniyah 46001, Kurdistan, Iraq.
LA  - eng
PT  - Journal Article
DEP - 20230303
PL  - United States
TA  - Am J Otolaryngol
JT  - American journal of otolaryngology
JID - 8000029
SB  - IM
MH  - Humans
MH  - *Turbinates/surgery
MH  - Prospective Studies
MH  - Treatment Outcome
MH  - *Endoscopy
MH  - Pituitary Gland
OTO - NOTNLM
OT  - Endoscopic trans-nasal trans-sphenoidal surgery
OT  - Middle turbinate
OT  - Olfaction
OT  - Pituitary adenoma
OT  - Skull base surgery
COIS- Conflict of interest The authors declare that they have no conflict of interest.
EDAT- 2023/03/11 06:00
MHDA- 2023/05/01 06:42
CRDT- 2023/03/10 18:05
PHST- 2022/11/29 00:00 [received]
PHST- 2023/02/24 00:00 [revised]
PHST- 2023/02/25 00:00 [accepted]
PHST- 2023/05/01 06:42 [medline]
PHST- 2023/03/11 06:00 [pubmed]
PHST- 2023/03/10 18:05 [entrez]
AID - S0196-0709(23)00040-6 [pii]
AID - 10.1016/j.amjoto.2023.103826 [doi]
PST - ppublish
SO  - Am J Otolaryngol. 2023 May-Jun;44(3):103826. doi: 10.1016/j.amjoto.2023.103826. 
      Epub 2023 Mar 3.