PMID- 36910847
OWN - NLM
STAT- PubMed-not-MEDLINE
LR  - 20230314
IS  - 2364-3722 (Print)
IS  - 2196-9736 (Electronic)
IS  - 2196-9736 (Linking)
VI  - 11
IP  - 3
DP  - 2023 Mar
TI  - Efficacy and safety of repeated endoscopic radial incision and cutting procedure 
      for benign esophageal stricture.
PG  - E230-E236
LID - 10.1055/a-2005-7678 [doi]
AB  - Background and study aims: Radial incision and cutting (RIC) is indicated for 
      refractory benign esophageal strictures after curative treatment for esophageal 
      cancer and has shown favorable short-term outcomes. However, re-stricture after 
      RIC may occur in the long term, and RIC is performed repeatedly in such cases, 
      but the efficacy and safety of repeated RIC are unclear. Therefore, we aimed to 
      demonstrate the efficacy and safety of the repeated RIC for refractory benign 
      esophageal strictures after surgical and non-surgical treatment. Patients and 
      methods: Between April 2008 and September 2019, we enrolled patients who were 
      treated with the first RIC for benign esophageal strictures. The RIC was 
      indicated for the refractory stricture and repeatedly performed for re-refractory 
      esophageal stricture after RIC. We retrospectively evaluated the 6-month 
      refractory stricture-free rate, and adverse events (AEs) in the first RIC and 
      repeated RICs. Results: Forty-six patients (39 men, 7 women; median age, 71 
      years, range 49-85) were included. RIC was performed once in 24 patients 
      (non-repeated RIC group) and two or more times in 22 patients (repeated RIC 
      group). In all patients, the 6-month refractory stricture-free rate after the 
      first RIC were 42.3 %. In the repeated RIC group, the 6-month refractory 
      stricture-free rate after the first and repeated RICs were 18.2 % vs 18.2 %, 
      respectively. No AEs were noted. Conclusions: Repeated RIC could be effective in 
      the short-term and safe even for patients with refractory benign esophageal 
      stricture after the first RIC. However, it cannot be considered curative 
      treatment for refractory stricture because of poor long-term results.
CI  - The Author(s). This is an open access article published by Thieme under the terms 
      of the Creative Commons Attribution-NonDerivative-NonCommercial License, 
      permitting copying and reproduction so long as the original work is given 
      appropriate credit. Contents may not be used for commercial purposes, or adapted, 
      remixed, transformed or built upon. 
      (https://creativecommons.org/licenses/by-nc-nd/4.0/).
FAU - Kano, Yuki
AU  - Kano Y
AD  - Department of Gastroenterology and Endoscopy, National Cancer Center Hospital 
      East, Kashiwa, Chiba, Japan.
AD  - Course of Advanced Clinical Research of Cancer, Juntendo University Graduate 
      School of Medicine, Tokyo, Japan.
FAU - Kadota, Tomohiro
AU  - Kadota T
AD  - Department of Gastroenterology and Endoscopy, National Cancer Center Hospital 
      East, Kashiwa, Chiba, Japan.
FAU - Inaba, Atsushi
AU  - Inaba A
AD  - Department of Gastroenterology and Endoscopy, National Cancer Center Hospital 
      East, Kashiwa, Chiba, Japan.
FAU - Sunakawa, Hironori
AU  - Sunakawa H
AD  - Department of Gastroenterology and Endoscopy, National Cancer Center Hospital 
      East, Kashiwa, Chiba, Japan.
FAU - Takashima, Kenji
AU  - Takashima K
AD  - Department of Gastroenterology and Endoscopy, National Cancer Center Hospital 
      East, Kashiwa, Chiba, Japan.
FAU - Nakajo, Keiichiro
AU  - Nakajo K
AD  - Department of Gastroenterology and Endoscopy, National Cancer Center Hospital 
      East, Kashiwa, Chiba, Japan.
FAU - Murano, Tatsuro
AU  - Murano T
AD  - Department of Gastroenterology and Endoscopy, National Cancer Center Hospital 
      East, Kashiwa, Chiba, Japan.
FAU - Shinmura, Kensuke
AU  - Shinmura K
AD  - Department of Gastroenterology and Endoscopy, National Cancer Center Hospital 
      East, Kashiwa, Chiba, Japan.
FAU - Yoda, Yusuke
AU  - Yoda Y
AD  - Department of Gastroenterology and Endoscopy, National Cancer Center Hospital 
      East, Kashiwa, Chiba, Japan.
FAU - Ikematsu, Hiroaki
AU  - Ikematsu H
AD  - Department of Gastroenterology and Endoscopy, National Cancer Center Hospital 
      East, Kashiwa, Chiba, Japan.
FAU - Akimoto, Tetsuo
AU  - Akimoto T
AD  - Course of Advanced Clinical Research of Cancer, Juntendo University Graduate 
      School of Medicine, Tokyo, Japan.
AD  - Department of Radiation Oncology, National Cancer Center Hospital East, Kashiwa, 
      Japan.
FAU - Yano, Tomonori
AU  - Yano T
AD  - Department of Gastroenterology and Endoscopy, National Cancer Center Hospital 
      East, Kashiwa, Chiba, Japan.
LA  - eng
PT  - Journal Article
DEP - 20230308
PL  - Germany
TA  - Endosc Int Open
JT  - Endoscopy international open
JID - 101639919
PMC - PMC9995178
COIS- Competing interests The authors declare that they have no conflict of interest.
EDAT- 2023/03/14 06:00
MHDA- 2023/03/14 06:01
PMCR- 2023/03/01
CRDT- 2023/03/13 04:17
PHST- 2022/09/03 00:00 [received]
PHST- 2022/12/20 00:00 [accepted]
PHST- 2023/03/13 04:17 [entrez]
PHST- 2023/03/14 06:00 [pubmed]
PHST- 2023/03/14 06:01 [medline]
PHST- 2023/03/01 00:00 [pmc-release]
AID - 10.1055/a-2005-7678 [doi]
PST - epublish
SO  - Endosc Int Open. 2023 Mar 8;11(3):E230-E236. doi: 10.1055/a-2005-7678. 
      eCollection 2023 Mar.