PMID- 36914524 OWN - NLM STAT- MEDLINE DCOM- 20230411 LR - 20231130 IS - 1836-9561 (Electronic) IS - 1836-9561 (Linking) VI - 69 IP - 2 DP - 2023 Apr TI - In adults with advanced lung disease, the 1-minute sit-to-stand test underestimates exertional desaturation compared with the 6-minute walk test: an observational study. PG - 108-113 LID - S1836-9553(23)00002-4 [pii] LID - 10.1016/j.jphys.2023.02.001 [doi] AB - QUESTION: In adults with advanced lung disease, do the 6-minute walk test (6MWT) and 1-minute sit-to-stand test (1minSTS) elicit similar cardiorespiratory responses? Can the 6-minute walk distance (6MWD) be estimated from the 1minSTS result? DESIGN: Prospective observational study using data collected during routine clinical practice. PARTICIPANTS: Eighty adults (43 males) with advanced lung disease, a mean age of 64 years (SD 10) and a mean forced expiratory volume in 1 second of 1.65 L (SD 0.77). OUTCOME MEASURES: Participants completed a 6MWT and a 1minSTS. During both tests, oxygen saturation (SpO(2)), pulse rate, dyspnoea and leg fatigue (Borg 0 to 10) were recorded. RESULTS: Compared with the 6MWT, the 1minSTS resulted in higher nadir SpO(2) (MD 4%, 95% CI 3 to 5), lower end-test pulse rate (MD -4 beats/minute, 95% CI -6 to -1), similar dyspnoea (MD -0.3, 95% CI -0.6 to 0.1) and greater leg fatigue (MD 1.1, 95% CI 0.6 to 1.6). Among the participants who demonstrated severe desaturation (SpO(2) nadir < 85%) on the 6MWT (n = 18), five and ten participants were classified as moderate (nadir 85 to 89%) or mild desaturators (nadir >/= 90%), respectively, on the 1minSTS. The relationship between the 6MWD and 1minSTS was: 6MWD (m) = 247 + (7 x number of transitions achieved during the 1minSTS) with poor predictive ability (r(2) = 0.44). CONCLUSION: The 1minSTS elicited less desaturation than the 6MWT and classified a smaller proportion of people as 'severe desaturators' on exertion. It is therefore inappropriate to use the nadir SpO(2) recorded during a 1minSTS to make decisions about whether strategies are needed to prevent severe transient exertional desaturation during walking-based exercise. Further, the extent to which performance on the 1minSTS can estimate a person's 6MWD is poor. For these reasons, the 1minSTS is unlikely to be helpful when prescribing walking-based exercise. CI - Copyright (c) 2023 Australian Physiotherapy Association. Published by Elsevier B.V. All rights reserved. FAU - Watson, Kathryn AU - Watson K AD - Physiotherapy Department, Fiona Stanley Hospital, Perth, Australia. Electronic address: Kathryn.Watson@health.wa.gov.au. FAU - Winship, Peta AU - Winship P AD - Physiotherapy Department, Fiona Stanley Hospital, Perth, Australia; National School of Health Sciences and Physiotherapy, Notre Dame University, Perth, Australia. FAU - Cavalheri, Vinicius AU - Cavalheri V AD - Physiotherapy Department, Fiona Stanley Hospital, Perth, Australia; Allied Health, Metropolitan Health Service, Perth, Australia; Curtin School of Allied Health and enAble Institute, Curtin University, Perth, Australia. FAU - Vicary, Caitlin AU - Vicary C AD - Physiotherapy Department, Fiona Stanley Hospital, Perth, Australia. FAU - Stray, Stephanie AU - Stray S AD - Physiotherapy Department, Fiona Stanley Hospital, Perth, Australia. FAU - Bear, Natasha AU - Bear N AD - Institute for Health Research, Notre Dame University, Perth, Australia. FAU - Hill, Kylie AU - Hill K AD - Curtin School of Allied Health and enAble Institute, Curtin University, Perth, Australia. LA - eng PT - Journal Article PT - Observational Study DEP - 20230311 PL - Netherlands TA - J Physiother JT - Journal of physiotherapy JID - 101528691 SB - IM CIN - J Physiother. 2023 Jul;69(3):203. PMID: 37271693 MH - Male MH - Humans MH - Adult MH - Middle Aged MH - Walk Test MH - *Exercise Test/methods MH - *Pulmonary Disease, Chronic Obstructive MH - Dyspnea MH - Walking/physiology MH - Fatigue MH - Exercise Tolerance OTO - NOTNLM OT - 1-min STS Lung disease OT - Exercise testing 6MWT OT - Physical therapy EDAT- 2023/03/14 06:00 MHDA- 2023/04/11 06:41 CRDT- 2023/03/13 23:01 PHST- 2022/11/16 00:00 [received] PHST- 2023/01/12 00:00 [revised] PHST- 2023/02/09 00:00 [accepted] PHST- 2023/04/11 06:41 [medline] PHST- 2023/03/14 06:00 [pubmed] PHST- 2023/03/13 23:01 [entrez] AID - S1836-9553(23)00002-4 [pii] AID - 10.1016/j.jphys.2023.02.001 [doi] PST - ppublish SO - J Physiother. 2023 Apr;69(2):108-113. doi: 10.1016/j.jphys.2023.02.001. Epub 2023 Mar 11.