PMID- 36924376
OWN - NLM
STAT- MEDLINE
DCOM- 20230323
LR  - 20230502
IS  - 2282-4197 (Electronic)
IS  - 1124-3562 (Linking)
VI  - 95
IP  - 1
DP  - 2023 Mar 13
TI  - Evaluation of urodynamic pattern in short and long-standing diabetic patients.
PG  - 11072
LID - 10.4081/aiua.2023.11072 [doi]
AB  - PURPOSE: To address the pattern of urodynamic findings in diabetic patients with 
      lower urinary tract symptoms (LUTS), comparing short-standing and long-standing 
      type 2 diabetes mellitus (T2DM). METHODS: A prospective study was conducted on 50 
      patients presenting with LUTS and a concurrent diagnosis of T2DM, between 
      February 2016 and May 2018. Patients were classified and evaluated according to 
      the duration of diabetes into two groups: short-standing DM (< 15 years, n = 31), 
      and long-standing DM (>/= 15 years, n = 19) groups. The impact of LUTS and quality 
      of life were assessed in female patients using ICIQ-FLUTS and male patients using 
      ICIQ-MLUTS. RESULTS: A total of 50 patients were included in the study. The mean 
      duration of T2DM was 10 +/- 0.7 years. The mean age was 56.3 +/- 1.2 years, and the 
      mean HbA1c was 7.5 +/- 1.2%. Urodynamic evaluation detected significantly higher 
      detrusor overactivity (DO) and increased bladder sensation with the 
      short-standing DM group (35.5 vs. 15.8%, p = 0.01 and 32.3 vs. 5.3%, p = 0.01, 
      respectively). Comparatively, weak, or absent detrusor contractility were more 
      frequent in patients with long-standing DM (52% and 26% respectively p = 0.01). 
      As expected, overflow incontinence and straining during voiding were 
      significantly higher in the long-standing DM group (p = 0.04 and p = 0.03, 
      respectively). Surprisingly, there was no significant correlation between 
      patients presenting with urgency in their voiding diary (subjective) and 
      urodynamic detection of DO (p = 0.07). CONCLUSIONS: There are different patterns 
      in urodynamic characterizations of T2DM. Patients with short-standing DM present 
      more commonly with storage symptoms and detrusor overactivity on urodynamics. 
      Contrastingly, patients with long-standing DM present more frequently with 
      voiding symptoms and detrusor underactivity on urodynamics. Thus, screening for 
      an underactive bladder is advisable in patients with long-standing T2DM.
FAU - Elsakka, Haytham
AU  - Elsakka H
AD  - Urology Department, East Lancashire Hospitals NHS trust, Balckburn, Lancashire. 
      haythamurology@gmail.com.
FAU - Ibrahim, Ahmed
AU  - Ibrahim A
AD  - Department of Surgery, Division of Urology, McGill University Health Center, 
      Montreal QC. eldemerdash90@gmail.com.
FAU - Khogeer, Abdulghani
AU  - Khogeer A
AD  - Department of Surgery, Division of Urology, McGill University Health Center, 
      Montreal QC; Department of Surgery, Faculty of Medicine, Rabigh, King Abdulaziz 
      University, Jeddah, Saudi Arabia. dr-abdulghani@hotmail.com.
FAU - Elatreisy, Adel
AU  - Elatreisy A
AD  - Urology Department, Faculty of Medicine, Al-Azhar University, Cairo. 
      adel.elatreisy@azhar.edu.eg.
FAU - Elabbady, Rawan
AU  - Elabbady R
AD  - Department of Surgery, Division of Urology, McGill University Health Center, 
      Montreal QC. rawanelabbady93@hotmail.com.
FAU - Shalkamy, Osama
AU  - Shalkamy O
AD  - Urology Department, Faculty of Medicine, Al-Azhar University, Cairo. 
      Dr_shalkamy@azhar.edu.eg.
FAU - Khan, Ayesha
AU  - Khan A
AD  - Urology Department, East Lancashire Hospitals NHS trust, Balckburn, Lancashire. 
      Ayesha.khan@elht.nhs.uk.
FAU - Sadri, Iman
AU  - Sadri I
AD  - Department of Surgery, Division of Urology, McGill University Health Center, 
      Montreal QC. iman.sadri@mail.mcgill.ca.
FAU - AlShammari, Ahmad
AU  - AlShammari A
AD  - Department of Surgery, Division of Urology, McGill University Health Center, 
      Montreal QC. dr.shammar@gmail.com.
FAU - Khalifa, Ahmad
AU  - Khalifa A
AD  - Department of Surgery, Division of Urology, McGill University Health Center, 
      Montreal QC. khalifa.urology@gmail.com.
FAU - Carrier, Serge
AU  - Carrier S
AD  - Department of Surgery, Division of Urology, McGill University Health Center, 
      Montreal QC. serge.carrier@mcgill.ca.
FAU - Aube-Peterkin, Melanie
AU  - Aube-Peterkin M
AD  - Department of Surgery, Division of Urology, McGill University Health Center, 
      Montreal QC. Melanie.aube-peterkin@mcgill.ca.
LA  - eng
PT  - Journal Article
DEP - 20230313
PL  - Italy
TA  - Arch Ital Urol Androl
JT  - Archivio italiano di urologia, andrologia : organo ufficiale [di] Societa 
      italiana di ecografia urologica e nefrologica
JID - 9308247
SB  - IM
MH  - Humans
MH  - Male
MH  - Female
MH  - Middle Aged
MH  - *Diabetes Mellitus, Type 2/complications
MH  - Urodynamics
MH  - Quality of Life
MH  - Prospective Studies
MH  - *Lower Urinary Tract Symptoms/etiology
EDAT- 2023/03/17 06:00
MHDA- 2023/03/24 06:00
CRDT- 2023/03/16 06:33
PHST- 2022/12/07 00:00 [received]
PHST- 2023/01/06 00:00 [accepted]
PHST- 2023/03/17 06:00 [pubmed]
PHST- 2023/03/24 06:00 [medline]
PHST- 2023/03/16 06:33 [entrez]
AID - 10.4081/aiua.2023.11072 [doi]
PST - epublish
SO  - Arch Ital Urol Androl. 2023 Mar 13;95(1):11072. doi: 10.4081/aiua.2023.11072.