PMID- 36925630 OWN - NLM STAT- PubMed-not-MEDLINE LR - 20230318 IS - 2052-4374 (Print) IS - 2052-4374 (Electronic) IS - 2052-4374 (Linking) VI - 35 DP - 2023 TI - Risk assessment of heavy metals in tuna from Japanese restaurants in the Republic of Korea. PG - e3 LID - 10.35371/aoem.2023.35.e3 [doi] LID - e3 AB - BACKGROUND: Studies on the risk of mercury (Hg) in Korean fishery products focus primarily on total Hg levels as opposed to methylmercury (MeHg) levels. None of the few studies on MeHg in tuna investigated tuna from Japanese restaurants. Few have evaluated lead (Pb), cadmium (Cd) and arsenic (As) in tuna. Thus, this study aimed to conduct a risk assessment by evaluating heavy metal concentrations in tuna from Japanese restaurants. METHODS: Thirty-one tuna samples were collected from Japanese restaurants in the Republic of Korea. They were classified according to region and species. The concentration of heavy metals in the samples was analyzed using the Ministry of Food and Drug Safety Food Code method. The rate of exceedance of maximum residue levels (MRLs) and the risk compared to the provisional tolerable weekly intake (PTWI) set by the Joint Food and Agriculture Organization/World Health Organization Expert Committee on Food Additives (%PTWI) were evaluated for risk assessment. RESULTS: The mean of MeHg, Pb, Cd and As concentrations were 0.56 +/- 1.47 mg/kg, 33.95 +/- 3.74 mug/kg, 14.25 +/- 2.19 mug/kg and 1.46 +/- 1.89 mg/kg, respectively. No sample exceeded the MRLs of Pb and Cd, but 9.7% of the samples exceeded the MRL of MeHg. The %PTWIs of MeHg, Pb, Cd and As were 4.2037, 0.0162, 0.0244 and 1.1627, respectively. The %PTWI of MeHg by age group and sex was highest among men aged 19-29 years (10.6494), followed by men aged 30-49 years (7.2458) and women aged 19-29 years (4.8307). CONCLUSIONS: We found that 3 out of 31 samples exceeded the MRL of MeHg. The %PTWI of MeHg showed significant differences based on age and sex, and the value was likely to exceed a safe level depending on individuals' eating behaviors. Therefore, improved risk management for MeHg is required. CI - Copyright (c) 2023 Korean Society of Occupational & Environmental Medicine. FAU - Bae, Seong-Jin AU - Bae SJ AUID- ORCID: 0000-0001-9423-0381 AD - Department of Occupational and Environmental Medicine, Yeungnam University Hospital, Daegu, Korea. FAU - Shin, Kyu-Sik AU - Shin KS AUID- ORCID: 0000-0001-6330-2274 AD - Graduate School of Environment & Public Health Studies, Yeungnam University, Daegu, Korea. FAU - Park, Chulyong AU - Park C AUID- ORCID: 0000-0001-8584-5376 AD - Department of Occupational and Environmental Medicine, Yeungnam University Hospital, Daegu, Korea. AD - Department of Preventive Medicine and Public Health, College of Medicine, Yeungnam University, Daegu, Korea. FAU - Baek, Kiook AU - Baek K AUID- ORCID: 0000-0003-2822-8480 AD - Department of Occupational and Environmental Medicine, Yeungnam University Hospital, Daegu, Korea. FAU - Son, So-Young AU - Son SY AUID- ORCID: 0000-0001-5162-9739 AD - Department of Occupational and Environmental Medicine, Yeungnam University Hospital, Daegu, Korea. FAU - Sakong, Joon AU - Sakong J AUID- ORCID: 0000-0003-3623-7619 AD - Department of Occupational and Environmental Medicine, Yeungnam University Hospital, Daegu, Korea. AD - Department of Preventive Medicine and Public Health, College of Medicine, Yeungnam University, Daegu, Korea. LA - eng PT - Journal Article DEP - 20230209 PL - Korea (South) TA - Ann Occup Environ Med JT - Annals of occupational and environmental medicine JID - 101609244 PMC - PMC10011450 OTO - NOTNLM OT - Mercury OT - Metals, Heavy OT - Republic of Korea OT - Risk assessment OT - Tuna COIS- Competing interests: The authors declare that they have no competing interests. EDAT- 2023/03/18 06:00 MHDA- 2023/03/18 06:01 PMCR- 2023/02/09 CRDT- 2023/03/17 02:36 PHST- 2022/06/24 00:00 [received] PHST- 2022/11/01 00:00 [revised] PHST- 2022/12/26 00:00 [revised] PHST- 2022/12/26 00:00 [accepted] PHST- 2023/03/17 02:36 [entrez] PHST- 2023/03/18 06:00 [pubmed] PHST- 2023/03/18 06:01 [medline] PHST- 2023/02/09 00:00 [pmc-release] AID - 10.35371/aoem.2023.35.e3 [doi] PST - epublish SO - Ann Occup Environ Med. 2023 Feb 9;35:e3. doi: 10.35371/aoem.2023.35.e3. eCollection 2023.