PMID- 36928658
OWN - NLM
STAT- MEDLINE
DCOM- 20230321
LR  - 20230411
IS  - 1932-6203 (Electronic)
IS  - 1932-6203 (Linking)
VI  - 18
IP  - 3
DP  - 2023
TI  - Estonian adverse events study for multimorbid patients using Estonian Trigger 
      Tool (MUPETT-MUltimorbid Patients-Estonian Trigger Tool). Development of Estonian 
      trigger tool for multimorbid patients. A study protocol for mixed-methods study.
PG  - e0280200
LID - 10.1371/journal.pone.0280200 [doi]
LID - e0280200
AB  - INTRODUCTION: It is widely recognized that providing healthcare may produce harm 
      to the patient. Different approaches have been developed to measure the burden of 
      adverse events (AEs) to plan and measure the effects of interventions. One of the 
      most widely used instruments is the Trigger Tool, which has previously been 
      modified to be used on various settings and translated into many languages. 
      Multimorbidity complicates care and may increase the number of AEs patients 
      experience. Currently there is no instrument designed to measure AEs in 
      multimorbid patients. In Estonia, there is currently no validated instrument to 
      measure the burden of AEs. AIMS: The aim of this study will be evaluating the 
      characteristics and ocurrence of AEs in multimorbid patients in hospitalised 
      internal medicine patients of Estonia, and describes the development of a trigger 
      tool for this purpose. METHODS AND ANALYSIS: We will search for the evidence on 
      measuring AEs in the population of multimorbid patients focusing on trigger 
      tools, and synthesize the data. Data collection of the triggers from the 
      literature will be followed by translating triggers from English to Estonian. An 
      expert multidisciplinary panel will select the suitable triggers for this 
      population. Trigger tool will be pre-tested to assess agreement among 
      professionals and usability of the tool. Validation will be done using 90 medical 
      records. A cross-sectional study in internal medicine departments of two Estonian 
      tertiary care hospitals will be performed to identify the frequency and 
      characteristics of AEs in 960 medical records. We will also provide 
      preventability potential and influencing factors. DISSEMINATION: Results will be 
      disseminated to healthcare providers and stakeholders at national and 
      international conferences, and as a doctoral medical thesis.
CI  - Copyright: (c) 2023 Kannukene et al. This is an open access article distributed 
      under the terms of the Creative Commons Attribution License, which permits 
      unrestricted use, distribution, and reproduction in any medium, provided the 
      original author and source are credited.
FAU - Kannukene, Angela
AU  - Kannukene A
AUID- ORCID: 0000-0002-8172-6908
AD  - Department of Medicine, Institute of Clinical Medicine, University of Tartu, 
      Tartu, Estonia.
FAU - Orrego, Carola
AU  - Orrego C
AUID- ORCID: 0000-0002-2978-6268
AD  - Avedis Donabedian Research Institute (FAD), Universitat Autonoma de Barcelona, 
      Barcelona, Spain.
FAU - Lember, Margus
AU  - Lember M
AD  - Department of Medicine, Institute of Clinical Medicine, University of Tartu, 
      Tartu, Estonia.
AD  - Clinic of Internal Medicine, Tartu University Hospital, Tartu, Estonia.
FAU - Uuskula, Anneli
AU  - Uuskula A
AD  - Department of Medicine, Institute of Family Medicine and Public Health, 
      University of Tartu, Tartu, Estonia.
AD  - Clinic of Dermatology, Tartu Univeristy Hospital, Tartu, Estonia.
FAU - Polluste, Kaja
AU  - Polluste K
AD  - Department of Medicine, Institute of Clinical Medicine, University of Tartu, 
      Tartu, Estonia.
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
DEP - 20230316
PL  - United States
TA  - PLoS One
JT  - PloS one
JID - 101285081
SB  - IM
MH  - Humans
MH  - Estonia/epidemiology
MH  - *Medical Errors
MH  - Cross-Sectional Studies
MH  - *Multimorbidity
MH  - Patient Safety
MH  - Retrospective Studies
PMC - PMC10019657
COIS- The authors have declared that no competing interests exist.
EDAT- 2023/03/18 06:00
MHDA- 2023/03/22 06:00
PMCR- 2023/03/16
CRDT- 2023/03/17 09:22
PHST- 2022/12/15 00:00 [received]
PHST- 2022/12/21 00:00 [accepted]
PHST- 2023/03/17 09:22 [entrez]
PHST- 2023/03/18 06:00 [pubmed]
PHST- 2023/03/22 06:00 [medline]
PHST- 2023/03/16 00:00 [pmc-release]
AID - PONE-D-22-29842 [pii]
AID - 10.1371/journal.pone.0280200 [doi]
PST - epublish
SO  - PLoS One. 2023 Mar 16;18(3):e0280200. doi: 10.1371/journal.pone.0280200. 
      eCollection 2023.