PMID- 36930119
OWN - NLM
STAT- MEDLINE
DCOM- 20230321
LR  - 20230916
IS  - 1536-5964 (Electronic)
IS  - 0025-7974 (Print)
IS  - 0025-7974 (Linking)
VI  - 102
IP  - 11
DP  - 2023 Mar 17
TI  - Adjusted mortality of extracorporeal membrane oxygenation for acute myocardial 
      infarction patients in cardiogenic shock.
PG  - e33221
LID - 10.1097/MD.0000000000033221 [doi]
LID - e33221
AB  - Cardiogenic shock (CS) is a common cause of death following acute myocardial 
      infarction (MI). This study aimed to evaluate the adjusted mortality of 
      venoarterial extracorporeal membrane oxygenation (VA-ECMO) with intra-aortic 
      balloon counterpulsation (IABP) for patients with MI-CS. We included 300 MI 
      patients selected from a multinational registry and categorized into VA-ECMO + 
      IABP (N = 39) and no VA-ECMO (medical management +/- IABP) (N = 261) groups. Both 
      groups' 30-day and 1-year mortality were compared using the weighted 
      Kaplan-Meier, propensity score, and inverse probability of treatment weighting 
      methods. Adjusted incidences of 30-day (VA-ECMO + IABP vs No VA-ECMO, 77.7% vs 
      50.7; P = .083) and 1-year mortality (92.3% vs 84.8%; P = .223) along with 
      propensity-adjusted and inverse probability of treatment weighting models in 
      30-day (hazard ratio [HR], 1.57; 95% confidence interval [CI], 0.92-2.77; P = 
      .346 and HR, 1.44; 95% CI, 0.42-3.17; P = .452, respectively) and 1-year 
      mortality (HR, 1.56; 95% CI, 0.95-2.56; P = .076 and HR, 1.33; 95% CI, 0.57-3.06; 
      P = .51, respectively) did not differ between the groups. However, better 
      survival benefit 30 days post-ECMO could be supposed (31.6% vs 83.4%; P = .022). 
      Therefore, patients with MI-CS treated with IABP with additional VA-ECMO and 
      those not supported with ECMO have comparable overall 30-day and 1-year mortality 
      risks. However, VA-ECMO-supported survivors might have better long-term clinical 
      outcomes.
CI  - Copyright (c) 2023 the Author(s). Published by Wolters Kluwer Health, Inc.
FAU - Choe, Jeong Cheon
AU  - Choe JC
AD  - Department of Cardiology and Medical Research Institute, Pusan National 
      University Hospital, Busan, Korea.
FAU - Lee, Sun-Hack
AU  - Lee SH
AD  - Department of Cardiology and Medical Research Institute, Pusan National 
      University Hospital, Busan, Korea.
FAU - Ahn, Jin Hee
AU  - Ahn JH
AD  - Department of Cardiology and Medical Research Institute, Pusan National 
      University Hospital, Busan, Korea.
FAU - Lee, Hye Won
AU  - Lee HW
AD  - Department of Cardiology and Medical Research Institute, Pusan National 
      University Hospital, Busan, Korea.
FAU - Oh, Jun-Hyok
AU  - Oh JH
AD  - Department of Cardiology and Medical Research Institute, Pusan National 
      University Hospital, Busan, Korea.
FAU - Choi, Jung Hyun
AU  - Choi JH
AD  - Department of Cardiology and Medical Research Institute, Pusan National 
      University Hospital, Busan, Korea.
FAU - Lee, Han Cheol
AU  - Lee HC
AD  - Department of Cardiology and Medical Research Institute, Pusan National 
      University Hospital, Busan, Korea.
FAU - Cha, Kwang Soo
AU  - Cha KS
AD  - Department of Cardiology and Medical Research Institute, Pusan National 
      University Hospital, Busan, Korea.
FAU - Jeong, Myung Ho
AU  - Jeong MH
AD  - Division of Cardiology, Jeonnam National University Hospital, Gwangju, Korea.
FAU - Angiolillo, Dominick J
AU  - Angiolillo DJ
AD  - Division of Cardiology, University of Florida College of Medicine, Jacksonville, 
      FL.
FAU - Park, Jin Sup
AU  - Park JS
AUID- ORCID: 0000-0003-4262-5853
AD  - Department of Cardiology and Medical Research Institute, Pusan National 
      University Hospital, Busan, Korea.
LA  - eng
PT  - Journal Article
PL  - United States
TA  - Medicine (Baltimore)
JT  - Medicine
JID - 2985248R
SB  - IM
MH  - Humans
MH  - Shock, Cardiogenic/etiology
MH  - *Extracorporeal Membrane Oxygenation/methods
MH  - Intra-Aortic Balloon Pumping/adverse effects
MH  - *Myocardial Infarction/complications/therapy
MH  - Hospital Mortality
MH  - Retrospective Studies
PMC - PMC10019119
COIS- The authors have no conflicts of interest to disclose.
EDAT- 2023/03/18 06:00
MHDA- 2023/03/22 06:00
PMCR- 2023/03/17
CRDT- 2023/03/17 11:23
PHST- 2023/03/17 11:23 [entrez]
PHST- 2023/03/18 06:00 [pubmed]
PHST- 2023/03/22 06:00 [medline]
PHST- 2023/03/17 00:00 [pmc-release]
AID - 00005792-202303170-00056 [pii]
AID - 10.1097/MD.0000000000033221 [doi]
PST - ppublish
SO  - Medicine (Baltimore). 2023 Mar 17;102(11):e33221. doi: 
      10.1097/MD.0000000000033221.