PMID- 3693086
OWN - NLM
STAT- MEDLINE
DCOM- 19880204
LR  - 20181113
IS  - 0021-8782 (Print)
IS  - 1469-7580 (Electronic)
IS  - 0021-8782 (Linking)
VI  - 148
DP  - 1986 Oct
TI  - Lactate dehydrogenase isoenzyme changes during facial development.
PG  - 183-92
AB  - Lactate dehydrogenase activity (LDH) was demonstrated by a histochemical 
      technique in free, dissected, facial processes of rats from the ninth embryonic 
      day. Facial processes of embryonic rats aged 9-15 days were analysed by 
      isoelectric focusing for their isoenzymic distribution of LDH. A dominance of 
      LDH-5, LDH-4 and LDH-3 isoenzymes was observed. As a comparison, LDH isoenzymes 
      from mandibular and maxillary processes of rat embryos aged 9-11 days revealed 
      only LDH-5 and, to a smaller extent, LDH-4. These results constitute evidence for 
      prominent anaerobic metabolism in these tissues during early facial development. 
      Intense staining for LDH was seen in surface epithelium, respiratory epithelium 
      and in myogenic and osteogenic areas.
FAU - Granstrom, G
AU  - Granstrom G
AD  - Department of Histology, University of Gothenburg, Sweden.
FAU - Magnusson, B C
AU  - Magnusson BC
LA  - eng
PT  - Journal Article
PT  - Research Support, Non-U.S. Gov't
PL  - England
TA  - J Anat
JT  - Journal of anatomy
JID - 0137162
RN  - 0 (Isoenzymes)
RN  - EC 1.1.1.27 (L-Lactate Dehydrogenase)
SB  - IM
MH  - Animals
MH  - Embryonic and Fetal Development
MH  - Face/*embryology
MH  - Facial Bones/embryology/enzymology
MH  - Isoelectric Focusing
MH  - Isoenzymes
MH  - L-Lactate Dehydrogenase/*metabolism
MH  - Rats
MH  - Rats, Inbred Strains
PMC - PMC1261601
EDAT- 1986/10/01 00:00
MHDA- 1986/10/01 00:01
PMCR- 1986/10/01
CRDT- 1986/10/01 00:00
PHST- 1986/10/01 00:00 [pubmed]
PHST- 1986/10/01 00:01 [medline]
PHST- 1986/10/01 00:00 [entrez]
PHST- 1986/10/01 00:00 [pmc-release]
PST - ppublish
SO  - J Anat. 1986 Oct;148:183-92.