PMID- 36931525
OWN - NLM
STAT- MEDLINE
DCOM- 20230929
LR  - 20230929
IS  - 1879-1026 (Electronic)
IS  - 0048-9697 (Linking)
VI  - 877
DP  - 2023 Jun 15
TI  - Non-target analysis of organohalogenated contaminants in deep-sea fishes from the 
      Mediterranean Sea by comprehensive two-dimensional gas 
      chromatography-time-of-flight mass spectrometry.
PG  - 162873
LID - S0048-9697(23)01489-4 [pii]
LID - 10.1016/j.scitotenv.2023.162873 [doi]
AB  - The enhanced separation power and identification capabilities make comprehensive 
      two-dimensional gas chromatography-time-of-flight mass spectrometry 
      (GC x GC - ToF MS) a valuable instrumental alternative for non-target analysis 
      (NTA). In the present study, GC x GC - ToF MS has been used for the NTA of 
      chlorine- and bromine-containing compounds in composite livers of two scarcely 
      investigated Mediterranean deep-sea fish species, hollowsnout grenadier 
      (Coelorinchus caelorhincus) and roughsnout grenadier (Trachyrhinchus 
      trachyrhinchus). Attention focused on the identification of organohalogenated 
      compounds with structural characteristics similar to those of persistent organic 
      pollutants (POPs). In total, 116 Cl-, Br- and mixed Cl/Br-compounds were either 
      positively or tentatively identified in the analyzed liver samples. Up to 88 of 
      these compounds were legacy POPs, being polychlorinated biphenyls (PCBs) and 
      organochlorinated pesticides (OCPs) the most abundant and frequently detected 
      families. The other 28 identified POP-like compounds were analytes not considered 
      by current regulation and environmental monitoring programs, including, among 
      others, degradation products of specific OCPs, naturally produced organohalogen 
      compounds and several perchlorinated diethyldiphenylmethane-derivatives whose 
      presence in the investigated species is reported here for the first time. The 
      presence of other naturally occurring brominated and mixed halogenated compounds 
      in these fish species is also described for the first time. Our results also 
      showed differences in the accumulation profile of the identified compounds in 
      both species. Thereby, anthropogenic POPs showed higher relative abundances in 
      the livers of roughsnout grenadiers than those in hollowsnout grenadiers, while 
      for naturally occurring compounds the opposite trend or similar levels were found 
      in both species.
CI  - Copyright (c) 2023 The Authors. Published by Elsevier B.V. All rights reserved.
FAU - Escobar-Arnanz, J
AU  - Escobar-Arnanz J
AD  - Department of Instrumental Analysis and Environmental Chemistry, IQOG-CSIC, Juan 
      de la Cierva 3, 28006 Madrid, Spain.
FAU - Pena-Abaurrea, M
AU  - Pena-Abaurrea M
AD  - Department of Instrumental Analysis and Environmental Chemistry, IQOG-CSIC, Juan 
      de la Cierva 3, 28006 Madrid, Spain.
FAU - Santos, F J
AU  - Santos FJ
AD  - Department of Chemical Engineering and Analytical Chemistry, Faculty of 
      Chemistry, University of Barcelona, Diagonal 645, Barcelona 08028, Spain.
FAU - Ramos, L
AU  - Ramos L
AD  - Department of Instrumental Analysis and Environmental Chemistry, IQOG-CSIC, Juan 
      de la Cierva 3, 28006 Madrid, Spain. Electronic address: l.ramos@iqog.csic.es.
LA  - eng
PT  - Journal Article
DEP - 20230316
PL  - Netherlands
TA  - Sci Total Environ
JT  - The Science of the total environment
JID - 0330500
RN  - DFC2HB4I0K (Polychlorinated Biphenyls)
RN  - 0 (Water Pollutants, Chemical)
SB  - IM
MH  - Animals
MH  - Environmental Monitoring/methods
MH  - *Fishes/metabolism
MH  - Gadiformes
MH  - Gas Chromatography-Mass Spectrometry
MH  - Mediterranean Sea
MH  - *Polychlorinated Biphenyls/analysis
MH  - *Water Pollutants, Chemical/analysis
OTO - NOTNLM
OT  - Benthopelagic fishes
OT  - Comprehensive two-dimensional gas chromatography
OT  - Deep-sea
OT  - Non-target analysis
OT  - Organohalogenated compounds
OT  - Suspect analysis
COIS- Declaration of competing interest The authors declare no conflicts of interest.
EDAT- 2023/03/18 06:00
MHDA- 2023/05/08 06:42
CRDT- 2023/03/17 20:32
PHST- 2023/02/09 00:00 [received]
PHST- 2023/03/10 00:00 [revised]
PHST- 2023/03/10 00:00 [accepted]
PHST- 2023/05/08 06:42 [medline]
PHST- 2023/03/18 06:00 [pubmed]
PHST- 2023/03/17 20:32 [entrez]
AID - S0048-9697(23)01489-4 [pii]
AID - 10.1016/j.scitotenv.2023.162873 [doi]
PST - ppublish
SO  - Sci Total Environ. 2023 Jun 15;877:162873. doi: 10.1016/j.scitotenv.2023.162873. 
      Epub 2023 Mar 16.