PMID- 36933551
OWN - NLM
STAT- Publisher
LR  - 20230515
IS  - 1098-8785 (Electronic)
IS  - 0735-1631 (Linking)
DP  - 2023 Apr 24
TI  - Relationship between Ventricular Size on Latest Ultrasonogram and the Bayley 
      Scores >/= 18 Months in Extremely Low Gestational Age Neonates: A Retrospective 
      Cohort Study.
LID - 10.1055/a-2057-7454 [doi]
AB  - OBJECTIVE:  A ventricle-to-brain index (VBI) >0.35 is associated with low scores 
      on the Bayley Scales of Infant and Toddler Development, Third Edition (BSID-III) 
      in preterm infants with birth weight <1,250 g. However, VBI obtained at the third 
      ventricle has only moderate interobserver reliability. The objective of this 
      study was to test (1) reliability of VBI measured at the foramen of Monro on the 
      latest ultrasonogram (US) before discharge using the intraclass correlation 
      coefficient (ICC) and (2) the relationship between VBI and BSID-III scores at >/=18 
      months corrected age. STUDY DESIGN:  The present study is a single-center 
      retrospective cohort study. RESULTS:  The study included 270 preterm infants born 
      at 23(0/7) to 28(6/7) weeks of gestational age. The ICC of VBI between 
      independent measurements by two study radiologists on the first 50 patients was 
      0.934. Factors associated with the value of VBI included severe intraventricular 
      hemorrhage, bronchopulmonary dysplasia, and systemic steroid administration for 
      BPD but not postmenstrual age. In multivariate analysis, VBI was negatively and 
      independently associated with cognitive (p = 0.002), language (p = 0.004), and 
      motor (p < 0.001) BSID-III scores. The association between VBI and BSID-III 
      scores was observed even in infants in whom the latest US was obtained before 
      term equivalent age. The association between VBI and BSID-III scores was also 
      observed after excluding those with severe intraventricular hemorrhage. 
      CONCLUSION:  In this very preterm cohort the measurement of VBI had excellent 
      reliability. Moreover, VBI measurements were negatively associated with motor, 
      language, and cognitive BSID-III scores. KEY POINTS: . Mean values of VBI are 
      stable with postmenstrual age.. . Values at the foramen of Monro are reliable and 
      reproducible.. . VBI is negatively associated with Bayley scores.. . The 
      association is observed even before term age..
CI  - Thieme. All rights reserved.
FAU - Reis, Jordan D
AU  - Reis JD
AD  - Department of Pediatrics, Division of Neonatal-Perinatal Medicine, University of 
      Texas Southwestern Medical Center, Dallas, Texas.
AD  - Department of Pediatrics, Baylor Scott & White, Dallas, Texas.
FAU - Hagan, Timothy
AU  - Hagan T
AD  - Department of Radiology, University of Texas Southwestern Medical Center, Dallas, 
      Texas.
FAU - Heyne, Roy
AU  - Heyne R
AD  - Department of Pediatrics, Division of Neonatal-Perinatal Medicine, University of 
      Texas Southwestern Medical Center, Dallas, Texas.
FAU - Tolentino-Plata, Kristine
AU  - Tolentino-Plata K
AD  - Department of Pediatrics, Division of Neonatal-Perinatal Medicine, University of 
      Texas Southwestern Medical Center, Dallas, Texas.
FAU - Clarke, Rebekah
AU  - Clarke R
AD  - Department of Radiology, Children's Health, Dallas, Texas.
FAU - Brown, Larry S
AU  - Brown LS
AD  - Department of Pediatrics, Parkland Hospital and Health System, Dallas, Texas.
FAU - Rosenfeld, Charles R
AU  - Rosenfeld CR
AD  - Department of Pediatrics, Division of Neonatal-Perinatal Medicine, University of 
      Texas Southwestern Medical Center, Dallas, Texas.
FAU - Burchfield, Patti J
AU  - Burchfield PJ
AD  - Department of Pediatrics, Division of Neonatal-Perinatal Medicine, University of 
      Texas Southwestern Medical Center, Dallas, Texas.
FAU - Caraig, Maria
AU  - Caraig M
AD  - Department of Pediatrics, Division of Neonatal-Perinatal Medicine, University of 
      Texas Southwestern Medical Center, Dallas, Texas.
FAU - Brion, Luc P
AU  - Brion LP
AUID- ORCID: 0000-0002-6139-0132
AD  - Department of Pediatrics, Division of Neonatal-Perinatal Medicine, University of 
      Texas Southwestern Medical Center, Dallas, Texas.
LA  - eng
PT  - Journal Article
DEP - 20230424
PL  - United States
TA  - Am J Perinatol
JT  - American journal of perinatology
JID - 8405212
SB  - IM
COIS- None declared
EDAT- 2023/03/19 06:00
MHDA- 2023/03/19 06:00
CRDT- 2023/03/18 19:32
PHST- 2023/03/19 06:00 [pubmed]
PHST- 2023/03/19 06:00 [medline]
PHST- 2023/03/18 19:32 [entrez]
AID - 10.1055/a-2057-7454 [doi]
PST - aheadofprint
SO  - Am J Perinatol. 2023 Apr 24. doi: 10.1055/a-2057-7454.